Joint United Nations Programme on HIV/AIDS U. On the fast track to an AIDS free generation; the incredible journey of the global plan towards the elimination of new HIV infections by 2015 among children and keeping their mothers alive. Geneva Switzerland: UNAIDS; 2016.
UNICEF. Paediatric care and treatment New York 2018 [Available from: https://data.unicef.org/topic/hivaids/paediatric-treatment-and-care/. Accessed 17 Nov 2018.
Joint United Nations Programme on HIV/AIDS U. Fact Sheet: Global HIV & AIDS statictics - 2018. 2018 [Available from: http://www.unaids.org/en/resources/fact-sheet. Accessed 17 Nov 2018.
Joint United Nations Programme on HIV/AIDS U. 90–90-90 an ambitious target to help end the AIDS epidemic. Geneva Switzerland: UNAIDS; 2014.
Violari A, Cotton M, Gibb D, Babiker A, Steyn J, Madhi S, et al. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med. 2008;359(21):2233–44.
Article
CAS
Google Scholar
MOH/CSO/PEPFAR/ICAP/CDC/TDRC/UTH/UNZA. Zambia Population-Based HIV Impact Assessment ZAMPHIA 2015-2016. 2016.
Google Scholar
Joint United Nations Programme on HIV/AIDS U. Fact Sheets: Zambia 2017. Geneva, Switzerland2017 [Available from: http://www.unaids.org/en/regionscountries/countries/zambia. Accessed 18 Nov 2018.
Bolton-Moore C, Mubiana-Mbewe M, Cantrell RA, et al. Clinical outcomes and cd4 cell response in children receiving antiretroviral therapy at primary health care facilities in Zambia. JAMA. 2007;298(16):1888–99.
Article
CAS
Google Scholar
Dijk JH, Sutcliffe CG, Munsanje B, Sinywimaanzi P, Hamangaba F, Thuma PE, et al. HIV-infected children in rural Zambia achieve good immunologic and virologic outcomes two years after initiating antiretroviral therapy. PLoS One. 2011;6.
Davies M-A, May M, Bolton-Moore C, Chimbetete C, Eley B, Garone D, et al. Prognosis of children with HIV-1 infection starting antiretroviral therapy in southern Africa: a collaborative analysis of treatment programs. Pediatr Infect Dis J. 2014;33(6):608–16.
Article
Google Scholar
Davies M-A, Gibb D, Turkova A. Survival of HIV-1 vertically infected children. Curr Opin HIV AIDS. 2016;11(5):455–64 Web.
Article
CAS
Google Scholar
Koller M, Patel K, Chi BH, Wools-Kaloustian K, Dicko F, Chokephaibulkit K, et al. Immunodeficiency in Children Starting Antiretroviral Therapy in Low-, Middle-, and High-income countries. J Acquir Immune Defic Syndr (1999). 2015;68(1):62–72.
Ardura-Garcia C, Feldacker C, Tweya H, Chaweza T, Kalulu M, Phiri S, et al. Implementation and Operational Research: Early Tracing of Children Lost to Follow-Up From Antiretroviral Treatment: True Outcomes and Future Risks. J Acquir Immune Defic Syndr (1999). 2015;70(5):e160-e1e7.
Mutanga J, Raymond J, Towle M, Mutembo S, Fubisha R, Lule F, et al. Institutionalizing provider-initiated HIV testing and counselling for children: an observational case study from Zambia. PLoS One. 2012;7(4):e29656.
Article
CAS
Google Scholar
Kankasa C, Carter RJ, Briggs N, Bulterys M, Chama E, Cooper ER, et al. Routine Offering of HIV Testing to Hospitalized Pediatric Patients at University Teaching Hospital, Lusaka, Zambia: Acceptability and Feasibility. J Acquir Immune Defic Syndr (1999). 2009;51(2):202–208.
Stringer JA, Zulu I, Levy J, et al. Rapid scale-up of antiretroviral therapy at primary care sites in Zambia: feasibility and early outcomes. JAMA. 2006;296(7):782–93.
Article
CAS
Google Scholar
Ministry of Health Z. Zambia Consolidated Guidelines for Prevention and Treatment of HIV Infection. 2018.
Google Scholar
Newell M-L, Coovadia H, Cortina Borja M, Rollins N, Gaillard P, Dabis F. Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis. Lancet. 2004;364(9441):1236–43.
Article
Google Scholar
Chammartin F, Zürcher K, Keiser O, Weigel R, Chu K, Kiragga AN, et al. Outcomes of patients lost to follow-up in African antiretroviral therapy programs: individual patient data meta-analysis. Clin Infect Dis. 2018;67(11):1643–52.
Article
Google Scholar
Team RC. R: a language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2017.
Alboukadel Kassambara MK. survminer: Drawing Survival Curves using 'ggplot2'. R package version 040999. 2017;http://www.sthda.com/english/rpkgs/survminer/. Accessed 2 May 2017.
Therneau T. _A Package for Survival Analysis in S_. version 2.38. 2015. https://CRAN.R-project.org/package=survival. Accessed 27 Aug 2017.
van Dijk JH, Sutcliffe CG, Munsanje B, Sinywimaanzi P, Hamangaba F, Thuma PE, et al. HIV-infected children in rural Zambia achieve good immunologic and Virologic outcomes two years after initiating antiretroviral therapy. PLoS One. 2011;6(4):e19006.
Article
Google Scholar
Brophy JC, Hawkes MT, Mwinjiwa E, Mateyu G, Sodhi SK, Chan AK. Survival outcomes in a pediatric antiretroviral treatment cohort in southern Malawi. PLoS One. 2016;11(11):e0165772.
Article
Google Scholar
Cohen S, Smit C, van Rossum AMC, Fraaij PLA, Wolfs TFW, Geelen SPM, et al. Long-term response to combination antiretroviral therapy in HIV-infected children in the Netherlands registered from 1996 to 2012. AIDS. 2013;27(16):2567–75.
Article
CAS
Google Scholar
Wamalwa DC, Obimbo EM, Farquhar C, Richardson BA, Mbori-Ngacha DA, Inwani I, et al. Predictors of mortality in HIV-1 infected children on antiretroviral therapy in Kenya: a prospective cohort. BMC Pediatr. 2010;10:33.
Article
Google Scholar
Walker AS, Prendergast AJ, Mugyenyi P, Munderi P, Hakim J, Kekitiinwa A, et al. Mortality in the year following antiretroviral therapy initiation in HIV-infected adults and children in Uganda and Zimbabwe. Clin Infect Dis. 2012;55(12):1707–18.
Article
CAS
Google Scholar
Njom Nlend AE, Loussikila AB. Predictors of mortality among HIV-infected children receiving highly active antiretroviral therapy. Med Mal Infect. 2017;47(1):32–7.
Article
CAS
Google Scholar
Braitstein PBM, Dabis F. Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: comparison between low-income and high-income countries. Lancet. 2006;367(9513):817–24.
Article
Google Scholar
Cotton M, Violari A, Otwombe K, Panchia R, Dobbels E, Rabie H, et al. Early time-limited antiretroviral therapy versus deferred therapy in south African infants infected with HIV: results from the children with HIV early antiretroviral (CHER) randomised trial. Lancet. 2013;382(9904):1555–63.
Article
Google Scholar
Ministry of Health Z, National AIDS Council, Zambia. Zambia Country Report: Monitoring the declaration of commitment on HIV/AIDS and the Universal Access. Lusaka, Zambia; 2015 5/2/2017.
Marston M, Becquet R, Zaba B, Moulton L, Gray G, Coovadia H, et al. Net survival of perinatally and postnatally HIV-infected children: a pooled analysis of individual data from sub-Saharan Africa. Int J Epidemiol. 2011;40(2):385–96.
Article
Google Scholar
Luzuriaga K. Early combination antiretroviral therapy limits HIV-1 persistence in children. Annu Rev Med. 2016;67(1):201–13.
Article
CAS
Google Scholar
Wagner A, Slyker J, Langat A, Inwani I, Adhiambo J, Benki-Nugent S, et al. High mortality in HIV-infected children diagnosed in hospital underscores need for faster diagnostic turnaround time in prevention of mother-to-child transmission of HIV (PMTCT) programs. BMC Pediatr. 2015;15:10.
Article
Google Scholar
Central Statistics Office MoH, Tropical Disease Research Centre University of Zambia and Macro International Inc. Zambia Demographic and Health Survey Maryland, USA: ICF International Rockville; 2014. p. 13–4.; 2013-2014.
Mundi I. Zambia-Mortality rate 2015 [Available from: https://www.indexmundi.com/facts/zambia/mortality-rate. Accessed 21 Aug 2017.
Boulware DR, Callens S, Pahwa S. Pediatric HIV immune reconstitution inflammatory syndrome. Curr Opin HIV AIDS. 2008;3(4):461–7.
Article
Google Scholar
Escamilla V, Chibwesha CJ, Gartland M, Chintu N, Mubiana-Mbewe M, Musokotwane K, et al. Distance from household to clinic and its association with the uptake of prevention of mother-to-child HIV transmission regimens in rural Zambia. J Acquir Immune Defic Syndr (1999). 2015;70(3):e94-e101.
Sam-Agudu NA, Ramadhani HO, Isah C, Erekaha S, Fan-Osuala C, Anaba U, et al. The Impact of Structured Mentor Mother Programs on Presentation for Early Infant Diagnosis Testing in Rural North-Central Nigeria: A Prospective Paired Cohort Study. J Acquir Immune Defic Syndr (1999). 2017;75:S182-S1S9.