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Table 2 Baseline laboratory and clinical features of infants and children who received ART at Livingstone Central Hospital, Zambia (2003–2015)

From: Long-term survival outcomes of HIV infected children receiving antiretroviral therapy: an observational study from Zambia (2003–2015)

Characteristics < 1 year 1–5 years 6–15 years Total
N = 179 (17%) N = 387 (37%) N = 473 (46%) N = 1039
CD4 count at enrollment Median (IQR) 1028 (535–1498) 777 (444–1135) 278 (118–487) 505 (243–948)
CD4 percent at enrollment Median(IQR) 19.4 (12.4–25.6) 16.7 (11.3–21.5) 14.0 (8.3–21.2) 16.2 (10–23)
Hemoglobin at enrollment (Median IQR)) 8.8 (7.8–9.7) 9.3 (8.0–10.5) 10.3 (9–11.5) 9.6 (8.3–10.9)
Taking Cotrimoxazole at enrollment
 Yes 169 (17%) 378 (38%) 451 (45%) 1000
 No 9 (23%) 8 (21%) 22 (56%) 39
Drug regimen at ART initiation N(%)
 3 NRTI’s 30 (38%) 46 (59%) 2 (3%) 78
 2NRTIs +1NNRTI 130 (14%) 320 (35%) 457 (50%) 907
 LPV/r based 19 (35%) 21 (39%) 14 (26%) 54
Year of ART start N(%)
 2003–2005 3 (4%) 17 (24%) 51 (72%) 71
 2006–2009 88 (17%) 202 (39%) 222 (43%) 512
 2010–2012 62 (20%) 117 (38%) 126 (41%) 305
 2013–2016 26 (17%) 51 (34%) 74 (49%) 151
Mom took ARVs for PMTCT during pregnancy
 Yes 69 (45%) 71 (46%) 14 (9%) 154
 No 110 (12%) 316 (36%) 459 (52%) 885
Child took ARV prophylaxis after birth N(%)
 Yes 55 (43%) 58 (47%) 8 (10%) 123
 No 124 (14%) 329 (36%) 463 (51%) 810
Nutritional status at enrollment
 Weight for height score < -3SD 36 (20%) 88 (48%) 58 (32%) 182
 weight for height score > −3 SD 143 (17%) 299 (35%) 415 (48%) 857
Baseline clinical staging (WHO stage) N(%)
 WHO stage 1 52 (24%) 64 (29%) 103 (47%) 219
 WHO stage 2 20 (13%) 39 (25%) 99 (63%) 158
 WHO stage 3 65 (14%) 200 (43%) 206 (44%) 471
 WHO stage 4 41 (23%) 78 (44%) 58 (33%) 177
 missing 1 6 7 14
Diseases at baseline N(%)
 TB 33 (10%) 105 (33%) 178 (56%) 318
 pneumonia 35 (21%) 68 (41%) 61 (27%) 165
 Diarrhea 45 (18%) 117 (47%) 84 (34%) 247
Gestation age at birth N(%)
 Premature 4 (25%) 8 (50%) 4 (25%) 16
 term 107 (22%) 201 (41%) 175 (36%) 485
 unknown 68 (13%) 178 (33%) 294 (54%) 544
Mode of delivery N(%)
 C/Section 5 (28%) 3 (17%) 10 (56%) 18
 SVD 105 (21%) 206 (42%) 180 (37%) 491
 unknown 69 (13%) 178 (34%) 283 (53%) 530