Skip to main content

Contrasting patterns of overweight and thinness among preschool children of different ethnic groups in Norway, and relations with maternal and early life factors

Abstract

Background

Childhood obesity is a worldwide health challenge and risk factor for adult life obesity, which predisposes to development of type 2 diabetes and cardiovascular diseases. However, also thinness in early life has been related to these diseases, especially if followed by fat gain. In European countries, susceptibility to cardio-metabolic diseases varies considerably between ethnic groups. We investigated ethnic differences in overweight and thinness in a multi-ethnic, population-based cohort of preschool children in Norway, and associations with maternal and early postnatal factors.

Methods

Participants were children aged 4–5 years (n = 570) drawn from the population-based STORK Groruddalen cohort of healthy women and offspring followed from early pregnancy. Ethnic groups were: European (n = 298), South Asian (n = 154), and Middle East/North African (n = 118). Children’s growth data were provided from routine visits at local Child Health Clinics. Weight status was defined by the International Obesity Task Force. Using multinomial logistic regression analysis, we explored ethnic differences in overweight and thinness, and associations with maternal-, pre, − and postnatal factors.

Results

Children of Middle East/North African origin had higher prevalence of overweight (22.0%) compared to European (12.8%) children, and in adjusted logistic regression analysis almost the double risk (OR 1.98; 95%CI: 1.08–3.63). Prevalence was lower in children of South Asian origin (5.2%). Children with South Asian background had higher prevalence of thinness (26.0%) compared to ethnic Europeans (10.4%), and the double risk (OR 2.20; 95%CI: 1.25–3.87) in adjusted models. Applying newly suggested BMI adjustments in South Asian children, taking into account their relatively increased adiposity, markedly increased the prevalence of overweight, and decreased the prevalence of thinness in this subgroup. Birthweight and maternal prepregnant overweight were strongly, positively associated with overweight, and inversely associated with thinness. Lower maternal age was associated with overweight only.

Conclusions

In a multi-ethnic cohort we found strikingly different patterns of overweight and thinness among children of different ethnic groups at age 4–5 years, and a strong association between maternal BMI and their children’s weight status. More knowledge is needed on what characterizes and what promotes healthy growth patterns in multi-ethnic populations.

Peer Review reports

Background

An increase in the prevalence of overweight and obesity among preschool children has been widely reported over the last decades. This represents a serious public health challenge [1]. Currently, the majority of children with overweight live in low- and middle-income countries where the overall prevalence is still increasing [1]. In European preschool children, the prevalence of overweight seems to have reached a plateau during the last years, although the prevalence varies considerably between countries. The rates tend to be higher in girls than in boys [2,3,4]. Findings indicate that some ethnic minority children with Middle East or North-African origin may be disproportionally affected by childhood overweight [4, 5], while other ethnic minorities, such as South Asian children, may have lower risk [6].

Childhood overweight and obesity have been associated with maternal factors such as prepregnant overweight and obesity, low socioeconomic position, and gestational diabetes mellitus [7,8,9]. Further, high birth weight and rapid weight gain in infancy also increase the risk [9]. Childhood overweight is a strong predictor for adult obesity and increases the risk of insulin resistance, type 2 diabetes, and cardiovascular diseases [10, 11].

However, cohort studies with long-term follow-up indicate that thinness at birth and early childhood may also be a risk factor for type 2 diabetes and cardiovascular disease, in particular if followed by an increase in body mass index (BMI) later in life [12,13,14,15]. This growth pattern most likely represents low lean mass from birth, which tracks throughout adult life, followed by accumulation of fat mass later in life. This “thin-fat phenotype” increases the risk of later cardio-metabolic diseases, but is not necessarily linked to adult overweight as defined by a high BMI [15,16,17]. Some ethnic groups, particularly South Asian populations, have an increased risk for type 2 diabetes and cardiovascular disease for a given BMI compared to populations with European or African origin. The susceptibility of South Asians is believed to be partly explained by their predisposition to a thin-fat phenotype already from birth [13, 18, 19]. By measuring body fatness in a multi-ethnic population of children in UK, Hudda et al. showed that BMI underestimated body fat in South Asian children, and suggested a positive adjustment of BMI of + 1.12 kg/m2 to account for greater relative adiposity in this population [20].

Pregnancy, the postpartum period, and early childhood are increasingly recognized as underused windows of opportunity to improve public health in the short and longer term [21]. In Norway, as in many other countries, pregnant women and their children are followed up regularly at Child Health Clinics. Increased knowledge about factors influencing overweight and thinness in multi-ethnic child-populations could contribute to an improved identification of children at risk, who could be offered targeted interventions in early life with the potential to reduce ethnic and social differences in health [22]. The aim of the current study was to investigate ethnic differences in overweight and thinness in a multi-ethnic, population-based cohort of preschool children in Norway, and associations with maternal and early postnatal factors.

Methods

Design and study population

The data were drawn from a prospective, population based cohort study, STORK Groruddalen, of 823 healthy pregnant women living in North-East Oslo [23]. Pregnant women were eligible for the study if they were 1) living in one of 3 city districts in Groruddalen; 2) planning to give birth at one of the 2 study hospitals; 3) at ≤20 weeks’ gestation; 4) not having pre-pregnancy diabetes or other diseases requiring intensive hospital follow-up during pregnancy; 5) able to communicate in Norwegian or any of the 8 languages to which all the information materials and questionnaires were translated (Arabic, English, Sorani, Somali, Tamil, Turkish, Urdu and Vietnamese); and 6) able to give informed written consent. While attending prenatal care at the Child Health Clinic, women were enrolled at mean 15 weeks of gestation, from 2008 to 2010. The Groruddalen area has a population that covers a large span in socioeconomic status, and has a high proportion of ethnic minorities. Of the study population, 59% had ethnic minority background. Questionnaire data were collected by specially trained midwifes through interview, supported by a professional interpreter when needed.

Outcome variable

Virtually all children in Norway attend a Child Health Clinic regularly for vaccinations and check-ups. For this study we used children’s growth data from the routine preschool visit performed at age 4–5 years at the local Child Health Clinic. Trained child health care nurses measured weight, to the nearest 100 g and height, to the nearest 0.1 cm. BMI was calculated as weight/height2 (kg/m2). Our outcome variable was weight status at age 4–5, classified as an ordinal variable with 4 levels: “thinness”, “normal weight”, “overweight” and “obesity” using the age- and sex-specific BMI cut-off values (z-scores) defined by the International Obesity Task Force [24]. These cut-off values correspond to centile curves passing through BMI 18.5 (thinness grade 1), 25 (overweight) and 30 (obesity) at age 18 years. In the regression analysis, the overweight and obesity group were merged and referred to as “overweight”.

Exposure variables

We chose exposure variables according to the literature and availability. The following variables were collected by interviews and questionnaires at inclusion:

Ethnicity was considered the main exposure variable and defined by the child’s mother or maternal grandmother’s country of birth if this country was outside Europe. We had information on 81% of fathers. Based on these data and clinical experience, there were very few children of mixed ethnicity (< 5% of ethnic European, South Asians and children with Middle East / North African origin). For this study we chose to focus on results for 3 main ethnic groupings: 1) Europeans (primarily from Norway and other Scandinavian countries); 2) South Asians (primarily from Pakistan and Sri Lanka); 3) Middle East/North Africans (primarily from Iraq, Turkey, Morocco, Afghanistan, Somalia, and Ethiopia).

Mother’s pre pregnant BMI was used as a categorical variable based on measured height and self-reported pre-pregnancy weight at inclusion [23], divided into three levels: Thinness (BMI < 18.5 kg/m2), normal weight (BMI 18.5–25 kg/m2) and overweight including obesity (BMI > 25 kg/m2).

Education was defined as an ordinal variable: Lower level (primary education or less), middle level (completed high school/upper secondary), and higher level (completed university/university-college education ≥4 years).

Prepregnant physical activity was self-reported and collected by a questionnaire that is previously validated against a physical activity monitor [25]. This variable is defined as moderately intensive activity for 30 min for ≥5 days/week, moderately intensive activity for 2.5 h/week over ≥3 days, vigorous-intensity activity for ≥20 min 3 times per week, or activity of both moderate and vigorous intensity (e.g., vigorous activity once per week and moderate activity twice per week). Prepregnant physical activity < 1 year prior to pregnancy was coded as never. Prepregnant physical activity > 1 year prior to pregnancy was coded as regular.

Mother’s dietary patterns were collected in week 28 of pregnancy, through a food frequency questionnaire, and defined by cluster analysis on 55 variables of intake and dichotomized into healthy and unhealthy [26].

Gestational diabetes mellitus was for this study defined according the WHO2013 criteria; fasting glucose ≥5.1 mmol/l and/or 2-h plasma glucose ≥8.5 mmol/l. A glucose tolerance test was performed in gestational week 28.

Other variables

Age at enrolment was used as continuous variable, and parity dichotomized as nulliparous and parous. Child birthweight to the nearest gram was routinely collected at birth on calibrated electronic scales [27]. Breast feeding was based on self-reports at 14 weeks postpartum and categorized as any and no breastfeeding. Maternal smoking status was also considered as covariate, but as very few of the ethnic minority women smoked, this variable was left out from the analyses.

Sample size

Of 823 women enrolled in early pregnancy, 784 singleton live born neonates with valid birth data were born (Fig. 1, flow chart). Of these neonates, 158 were excluded due to prematurity, postnatal death, refused further participation, family moved abroad or mother changed social security number, no data from Child Health Clinics outside Oslo, or missing data at Child Health Clinic at age 4–5 years. At last, 56 children from smaller and heterogeneous ethnic groups (East Asia, South- and Central America, and Sub- Saharan African countries) were excluded. The final study sample consisted of 570 children from 3 ethnic groups; 298 (52.3%) ethnic Europeans, 154(27.0%) ethnic South Asians, and 118 (20.7%) with Middle East/North African ethnicity.

Fig. 1
figure1

Flow chart

Statistical analysis

Descriptive statistics are given as frequencies, proportions (%), and means with standard deviation (SD). Differences in prevalence of thinness and overweight between the ethnic groups were assessed by Chi-square tests. Differences in children’s age were assessed by one-way ANOVA tests.

To investigate the impact of maternal and postnatal determinants on the child’s risk of overweight and thinness at the age of 4–5 years, we performed multinomial logistic regression analysis. Overweight and thinness were compared with normal weight children. Ethnic origin was the main exposure variable of interest (Europeans as reference). The following variables were considered potential covariates; maternal education, parity, age, prepregnant BMI and physical activity, diet during pregnancy, gestational diabetes mellitus, and child sex and birth weight. We selected variables into the multivariate model by a purposeful selection approach [28]. Variables with a p-value < 0.2 in the univariate analysis were included into the multivariate model. We removed one variable at a time, the variable with the highest p-value first, until all variables reached the level of significance (p < 0.05) in at least one of the models. For each step we checked if our main effect estimates (ethnicity) changed more than 15%. If so, the variable was kept in the model to take into account the potential confounding effect on the outcome. In the final model we tested for interactions with ethnicity by entering cross-product terms one-by–one. No significant interactions were observed. Results are shown as odd ratios (ORs) with 95% confidence intervals (CI). We included breast feeding into the multinomial logistic regression analysis of a subgroup with complete data at 14 weeks postpartum.

As it has been reported that children with South Asian origin have a higher fat mass for a given BMI than the other ethnic groups, we also performed positive BMI adjustments of + 1.12 kg/m2 for this group [20]. We then made a sensitivity logistic regression analysis using this adjusted classification of weight status for South Asians as outcome variable.

For all analyses we used SPSS version 22 (IBM SPSS statistics, NY, USA).

Results

Characteristics

Compared with European women, ethnic minority mothers were younger, had lower education, and higher parity. They were less physically active before pregnancy, and smoked less (Table 1). Prepregnant BMI was lower in South Asian women and higher in women from Middle East/North Africa. The prevalence of gestational diabetes mellitus was higher in ethnic minority mothers, and more minority women had a less healthy diet compared to ethnic European mothers. European children had higher birthweight than children in the other ethnic groups.

Table 1 Baseline characteristics

Prevalence of overweight and thinness at age 4–5 years

The prevalence of overweight was significantly higher in children of Middle East / North African origin (22.0% (14.5–29.6)) compared to children with European origin (12.8% (8.9–16.6)), while the prevalence in children with South Asian origin was significantly lower (5.2% (2.2–8.0)) (Table 2). In contrast, the prevalence of thinness was significantly higher in children with South Asian origin (26% (19.9–32.0) compared to children with European origin (10.4% (6.9–13.9)) and Middle East/North Africa origin (12.7% (6.6–18.8)).). Taking account of the South Asian’s relatively increased adiposity, we made positive adjustments of BMI. After adjustments, prevalence of thinness changed from 26 to 3.9%, and prevalence of overweight changed from 5.2 to 14.3% (Table 2).

Table 2 Age and prevalence of thinness, overweight and obesity in children aged 4–5 years

We found strong relations between mothers’ prepregnant weight status and the prevalence of overweight and thinness in the offspring. Of mothers with prepregnant overweight, 34% of Middle East/North African- and 19% of European mothers had children with overweight (Fig. 2). In contrast, 50% of South Asian mothers with thinness had children with thinness.

Fig. 2
figure2

Prevalence of child overweight (a) and thinness (b) by maternal prepregnant weight status in 3 different ethnic groups

Associations between maternal and early postnatal factors and overweight at age 4–5 years

Unadjusted multinomial logistic analysis (Table 3) showed that children of South Asian origin had 54% lower risk of overweight compared to European, while Middle East/North African origin had 2-fold (higher) risk. Maternal pre pregnancy overweight, low education, gestational diabetes mellitus, and child’s birthweight were also positively associated with overweight.

Table 3 Multinomial logistic regression for child overweight including obesity (A), and thinness (B), compared to normal weighted at age 4–5 years

In the adjusted model, Middle East/North African origin still nearly doubled the risk of being overweight (OR1.98; 95% CI:1.08–3.63). Maternal prepregnant overweight (OR 2.56; 95% CI: 1.52–4.61) and age (OR 0.93; 95% CI: 0.88–0.99), and child birthweight (OR1.11; 95% CI: 1.05–1.18) were independently and positively associated. Female sex was borderline significantly associated (OR1.73; 95% CI: 0.99–3.01). However, the negative effect estimate for South Asian origin was no longer statistically significant when adjusting for other factors. The association between maternal gestational diabetes and overweight in the offspring was more apparent in ethnic Europeans than in the ethnic minority groups. When formally testing for an interaction between ethnicity and gestational diabetes, however, the interaction was only borderline significant.

Associations between maternal and early postnatal factors and thinness at age 4–5 years

Unadjusted multinomial logistic analysis (Table 3) showed that children with South Asian origin had a 2.8-fold higher risk of thinness compared to those with European origin. Maternal pre pregnancy overweight and the child’s birth weight were negatively associated with thinness, while unhealthy diet was positively associated. The adjusted model showed that South Asian origin still doubled the risk of thinness (OR 2.20; 95% CI: 1.25–3.87). Prepregnant maternal overweight (OR0.50; 95% CI: 0.28–0.90) remained independently negatively associated with thinness at 4–5 years.

The sensitivity logistic regression analysis using the adjusted classification of weight status for South Asians (Additional file 1) shows that the South Asian children have a lower risk of thinness (OR 0.22; 95% CI: 0.08–0.60) compared to the European. This result contradicts the logistic regression analysis using unadjusted BMI for South Asian children (Table 3). However, the factors positively related to overweight (Middle East/North African origin, maternal age, prepregnant overweight, female sex and birth weight) remain significant in the sensitivity model.

Discussion

To the best of our knowledge, this study is the first population based study to assess both thinness and overweight in a multiethnic sample of children in Europe. We found strikingly different patterns of overweight and thinness among children of different ethnic groups at age 4–5 years. Compared to European children, children of Middle East/North African origin had almost the double risk of being overweight at 4–5 years of age. In contrast, South Asian origin almost doubled the risk of thinness. Applying newly suggested BMI adjustments in South Asian children, taking into account their relatively increased adiposity, markedly increased the prevalence of overweight and decreased the prevalence of thinness in this subgroup. Factors increasing the risk of overweight were maternal prepregnant overweight, lower maternal age, higher birthweight, and female sex. Maternal prepregnant overweight and higher birthweight reduced the risk of thinness. Our findings may be of great relevance for public health.

The overall prevalence of overweight and the prevalence in ethnic Europeans in our study were comparable with findings from another study of mainly ethnic Norwegian children. These data were collected in 2003–2006, and showed that in children aged 2–5 years, the prevalence of overweight was 12.7% [8]. Other European studies have only assessed either overweight or thinness. In two Dutch studies investigating overweight only, Turkish and Moroccan children had higher odds of being overweight compared to native Dutch children [4, 5]. In a British cross-sectional study investigating thinness only, the prevalence of thinness in British preschool children was 5.7%, while ethnic Asian children had an OR of 3.6 compared to white children [29]. The results from both these studies were in line with our findings.

In accordance with findings from other studies [5, 7, 30], maternal prepregnant overweight was a very strong predictor of childhood overweight. Nevertheless, it is largely unknown how much of this effect can be explained by a direct, causal relationship, for example mediated through maternal insulin resistance and inflammatory signals during pregnancy, and how much is mediated through genetics or shared life style factors [21].

Sex differences in childhood overweight vary in a global perspective [31]. In our study girls had more overweight than boys at age 4–5 years. Earlier Scandinavian studies show similar results at preschool age, but in older age groups there are more overweight in boys than in girls [8, 32].

Low socioeconomic status and low parental education have also been associated with childhood overweight [8, 30, 33]. We found no significant associations between maternal education and overweight at age 4–5 years. This might partly be due to lack of power, and that ethnicity also carries information about socioeconomic status [34]. However, other socioeconomic factors may be more important. A recent Swedish study showed that neighborhood purchasing power was more strongly related to overweight at age 4–5 years than parental educational levels [32]. This could be especially relevant in an immigrant population.

At the age of 4–5 years we found no association between gestational diabetes and offspring overweight. Studies investigating the possible link between gestational diabetes and offspring overweight show inconsistent results [35,36,37,38]. In a recent study from Hong Kong, maternal hyperglycemia in pregnancy was associated with adiposity in girls at age 7, but not in boys [36]. Our findings could suggest that also ethnicity may differentially affect this relation. Larger samples may be needed to study such effect modifications.

Other explanations of ethnic differences in overweight have been suggested. Perception of ideal BMI may vary between ethnic groups. Fatness may be associated with wealth, good health, beauty, strength, and happiness [39, 40]. In many countries, and in immigrant populations from Asia and the Middle East/North Africa, a shift from traditional food habits and entering a more sedentary life style has dramatically increased the prevalence of obesity and other risk factors for type 2 diabetes and cardiovascular diseases [41, 42].

The prevalence of thinness in the South Asian children at age 4–5 years in our study was significantly higher than in the other ethnic groups. Importantly, our definition of thinness is based on BMI z-score and does not necessarily reflect the children’s body composition. This was demonstrated in two UK studies showing that the adiposity levels were markedly higher in South Asian children than in white European children, despite lower BMI [20, 43]. In adulthood, the proportion of Asian people with a high risk of cardiovascular diseases and type 2 diabetes is substantial at BMIs lower than the WHO cut-off point for overweight [44]. However, estimated and suggested cut-off points for observed risk vary even between Asian populations and by outcomes [45]. As previously also shown in our cohort, neonates with South Asian ethnic origin are smaller and “thinner” at birth with smaller abdomen and less fat-free mass, but have relatively preserved fat mass [27]. This phenotype may result from in-utero programming after multigenerational malnutrition, tracks through life, and increases the risk of type 2 diabetes and cardiovascular disease [17, 18, 46]. Most of the South Asian children in our cohort had moderate thinness (clinically classified as grade 1 underweight). Hence, this is probably not a sign of illness, but rather due to lower lean mass. These children may be especially vulnerable if experiencing an increase in BMI; mainly representing an absolute and relative increase of fat tissue.

BMI underestimates total body fatness in South Asians. Positive BMI adjustments are suggested to make a more clinically relevant classification of weight class in children with South Asian origin [20] A recent UK study showed that when applying positive BMI adjustments in South Asian children living in England, the prevalence of thinness and overweight increased considerably in this group [47]. When applying the same BMI adjustments in our cohort of South Asian children, we also found marked changes in prevalence of thinness and overweight.

Our study suggests that health professionals should pay more attention to ethnic minority groups that are especially vulnerable to excess weight gain. On one hand, children of Middle East/North-African origin seem to have increased risk of developing overweight from early age. Overweight may persist into adult life and increase their risk of cardio-metabolic disease. On the other hand, children with South Asian origin have higher risk of thinness, probably reflecting low lean mass. This may increase their vulnerability to cardio-metabolic disease, especially if they experience excessive fat gain later in childhood or in adult life. Therefore, children who are thin from birth and in early childhood should receive earlier attention if they start crossing percentiles, and importantly, before they reach the “overweight threshold”. More research is needed before applying adjusted BMI classification based on ethnicity in a clinical setting. At Child Health Clinics and in general practice almost all children and pregnant women are followed over time from birth to adolescence and through pregnancies. This gives health professionals unique opportunities to promote healthy growth in children. Young girls and women in reproductive age can be targeted before, in, and in between pregnancies to prevent maternal overweight.

Strengths of the present study include the population-based cohort design, the large proportion of ethnic minorities that are often excluded in research, a very extensive and high quality data set, high attendance rate, and minor loss to follow-up. Limitations to this study should also be noted: Although anthropometric data on children were collected by trained Child Health Clinic personnel, they may be more inaccurate than if performed under standardized conditions. However, this probably applies equally to all ethnic groups. With 570 children in our cohort, power was limited, especially related to exploring potential effect modifications. Lifestyle characteristics, as diet and physical activity, are difficult to measure, and our variables may not represent all relevant variation. Due to small numbers for many countries of origin, we merged women into three larger ethnic groups. It cannot be ruled out that this may cause some bias because of within-group heterogeneity.

Conclusion

We found strikingly different patterns of overweight and thinness among children of different ethnic groups at 4–5 years of age; a finding with a great relevance to public health. Compared to the European children in our cohort, children with Middle East/North African background had almost the double risk of being overweight at age 4–5 years. Maternal prepregnant overweight and younger age, and higher child birthweight also increased this risk. In contrast, children with South Asian origin had almost the double risk of being classified as thin. However, applying suggested BMI adjustments in South Asian children, taking into account their relatively increased adiposity, markedly increased the prevalence of overweight, and decreased the prevalence of thinness in this group. The deviant and contrasting weight development in both of our ethnic minority groups could represent an increased vulnerability to contract cardiovascular diseases and type 2 diabetes in adult life. This adds to the complexity health workers need to be aware of. More knowledge is needed on how to tailor culturally sensitive health care for mothers and their children to promote healthy growth and prevent disease over the life course.

Abbreviations

BMI:

Body mass index

CI:

Confidence interval

OR:

Odds ratio

References

  1. 1.

    Ending Childhood Obesity http://www.who.int/end-childhood-obesity/final-report/en/. Accessed 25 Jan 2016.

  2. 2.

    Cattaneo A, Monasta L, Stamatakis E, Lioret S, Castetbon K, Frenken F, Manios Y, Moschonis G, Savva S, Zaborskis A, et al. Overweight and obesity in infants and pre-school children in the European Union: a review of existing data. Obes Rev. 2010;11(5):389–98.

    Article  PubMed  CAS  Google Scholar 

  3. 3.

    Health NIoP: Child Growth Study in Norway ; 2016.

    Google Scholar 

  4. 4.

    de Wilde JA, van Dommelen P, Middelkoop BJ, Verkerk PH. Trends in overweight and obesity prevalence in Dutch, Turkish, Moroccan and Surinamese south Asian children in the Netherlands. Arch Dis Child. 2009;94(10):795–800.

    Article  PubMed  CAS  Google Scholar 

  5. 5.

    de Hoog ML, van Eijsden M, Stronks K, Gemke RJ, Vrijkotte TG. Overweight at age two years in a multi-ethnic cohort (ABCD study): the role of prenatal factors, birth outcomes and postnatal factors. BMC Public Health. 2011;11:611.

    Article  PubMed  PubMed Central  Google Scholar 

  6. 6.

    Zilanawala A, Davis-Kean P, Nazroo J, Sacker A, Simonton S, Kelly Y. Race/ethnic disparities in early childhood BMI, obesity and overweight in the United Kingdom and United States. Int J Obes. 2015;39(3):520–9.

    Article  CAS  Google Scholar 

  7. 7.

    Godfrey KM, Reynolds RM, Prescott SL, Nyirenda M, Jaddoe VW, Eriksson JG, Broekman BF. Influence of maternal obesity on the long-term health of offspring. Lancet Diabetes Endocrinol. 2017;5(1):53–64.

    Article  PubMed  Google Scholar 

  8. 8.

    Juliusson PB, Eide GE, Roelants M, Waaler PE, Hauspie R, Bjerknes R. Overweight and obesity in Norwegian children: prevalence and socio-demographic risk factors. Acta Paediatr. 2010;99(6):900–5.

    Article  PubMed  Google Scholar 

  9. 9.

    Monasta L, Batty GD, Cattaneo A, Lutje V, Ronfani L, Van Lenthe FJ, Brug J. Early-life determinants of overweight and obesity: a review of systematic reviews. Obes Rev. 2010;11(10):695–708.

    Article  PubMed  CAS  Google Scholar 

  10. 10.

    Litwin SE. Childhood obesity and adulthood cardiovascular disease: quantifying the lifetime cumulative burden of cardiovascular risk factors. J Am Coll Cardiol. 2014;64(15):1588–90.

    Article  PubMed  Google Scholar 

  11. 11.

    Hrafnkelsson H, Magnusson KT, Sigurdsson EL, Johannsson E. Association of BMI and fasting insulin with cardiovascular disease risk factors in seven-year-old Icelandic children. Scand J Prim Health Care. 2009;27(3):186–91.

    Article  PubMed  PubMed Central  Google Scholar 

  12. 12.

    Whincup PH, Kaye SJ, Owen CG, Huxley R, Cook DG, Anazawa S, Barrett-Connor E, Bhargava SK, Birgisdottir BE, Carlsson S, et al. Birth weight and risk of type 2 diabetes: a systematic review. Jama. 2008;300(24):2886–97.

    Article  PubMed  CAS  Google Scholar 

  13. 13.

    Yajnik CS, Fall CH, Coyaji KJ, Hirve SS, Rao S, Barker DJ, Joglekar C, Kellingray S. Neonatal anthropometry: the thin-fat Indian baby. The Pune maternal nutrition study. Int J Obes and Relat Metab Disord. 2003;27(2):173–80.

    Article  CAS  Google Scholar 

  14. 14.

    Barker DJ, Osmond C, Forsen TJ, Kajantie E, Eriksson JG. Trajectories of growth among children who have coronary events as adults. N Engl J Med. 2005;353(17):1802–9.

    Article  PubMed  CAS  Google Scholar 

  15. 15.

    Eriksson JG, Kajantie E, Lampl M, Osmond C. Trajectories of body mass index amongst children who develop type 2 diabetes as adults. J Intern Med. 2015;278(2):219–26.

    Article  PubMed  CAS  Google Scholar 

  16. 16.

    Leunissen RW, Kerkhof GF, Stijnen T, Hokken-Koelega A. Timing and tempo of first-year rapid growth in relation to cardiovascular and metabolic risk profile in early adulthood. Jama. 2009;301(21):2234–42.

    Article  PubMed  CAS  Google Scholar 

  17. 17.

    Barker DJ. In utero programming of chronic disease. Clin Sci. 1998;95(2):115–28.

    Article  PubMed  CAS  Google Scholar 

  18. 18.

    Lear SA, Chockalingam A, Kohli S, Richardson CG, Humphries KH. Elevation in cardiovascular disease risk in south Asians is mediated by differences in visceral adipose tissue. Obesity. 2012;20(6):1293–300.

    Article  PubMed  CAS  Google Scholar 

  19. 19.

    de Wilde JA, Zandbergen-Harlaar S, van Buuren S, Middelkoop BJ. Trends in body mass index distribution and prevalence of thinness, overweight and obesity in two cohorts of Surinamese south Asian children in the Netherlands. Arch Dis Child. 2013;98(4):280–5.

    Article  PubMed  Google Scholar 

  20. 20.

    Hudda MT, Nightingale CM, Donin AS, Fewtrell MS, Haroun D, Lum S, Williams JE, Owen CG, Rudnicka AR, Wells JCK, et al. Body mass index adjustments to increase the validity of body fatness assessment in UK black African and south Asian children. Int J Obes. 2017;41(7):1048–55.

    Article  CAS  Google Scholar 

  21. 21.

    Catalano PM, Shankar K. Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child. Bmj. 2017;356:j1.

    Article  PubMed  Google Scholar 

  22. 22.

    Waters E, de Silva-Sanigorski A, Hall BJ, Brown T, Campbell KJ, Gao Y, Armstrong R, Prosser L, Summerbell CD. Interventions for preventing obesity in children. Cochrane Database Syst Rev. 2011;12:CD001871.

    Google Scholar 

  23. 23.

    Jenum AK, Sletner L, Voldner N, Vangen S, Morkrid K, Andersen LF, Nakstad B, Skrivarhaug T, Rognerud-Jensen OH, Roald B, et al. The STORK Groruddalen research programme: a population-based cohort study of gestational diabetes, physical activity, and obesity in pregnancy in a multiethnic population. Rationale, methods, study population, and participation rates. Scand J Public Health. 2010;38(5 Suppl):60–70.

    Article  PubMed  Google Scholar 

  24. 24.

    Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. Bmj. 2000;320(7244):1240–3.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  25. 25.

    Brantsaeter AL, Owe KM, Haugen M, Alexander J, Meltzer HM, Longnecker MP. Validation of self-reported recreational exercise in pregnant women in the Norwegian mother and child cohort study. Scand J Med Sci Sports. 2010;20(1):e48–55.

    Article  PubMed  CAS  Google Scholar 

  26. 26.

    Sommer C, Sletner L, Jenum AK, Morkrid K, Andersen LF, Birkeland KI, Mosdol A. Ethnic differences in maternal dietary patterns are largely explained by socio-economic score and integration score: a population-based study. Food Nutr Res. 2013;57 https://doi.org/10.3402/fnr.v57i0.21164.

  27. 27.

    Sletner L, Nakstad B, Yajnik CS, Morkrid K, Vangen S, Vardal MH, Holme IM, Birkeland KI, Jenum AK. Ethnic differences in neonatal body composition in a multi-ethnic population and the impact of parental factors: a population-based cohort study. PLoS One. 2013;8(8):e73058.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  28. 28.

    Hosmer DW, Lemeshow S. Applied logistic regression. 2nd ed. Hoboken: Wiley; 2005.

  29. 29.

    Whitaker KL, Jarvis MJ, Boniface D, Wardle J. The intergenerational transmission of thinness. Arch Pediatr Adolesc Med. 2011;165(10):900–5.

    Article  PubMed  Google Scholar 

  30. 30.

    van Rossem L, Hafkamp-de Groen E, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. The role of early life factors in the development of ethnic differences in growth and overweight in preschool children: a prospective birth cohort. BMC Public Health. 2014;14:722.

    Article  PubMed  PubMed Central  Google Scholar 

  31. 31.

    Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, Mullany EC, Biryukov S, Abbafati C, Abera SF, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the global burden of disease study 2013. Lancet. 2014;384(9945):766–81.

    Article  PubMed  PubMed Central  Google Scholar 

  32. 32.

    Roswall J, Almqvist-Tangen G, Holmen A, Alm B, Bergman S, Dahlgren J, Stromberg U. Overweight at four years of age in a Swedish birth cohort: influence of neighbourhood-level purchasing power. BMC Public Health. 2016;16:546.

    Article  PubMed  PubMed Central  Google Scholar 

  33. 33.

    Morgen CS, Andersen PK, Mortensen LH, Howe LD, Rasmussen M, Due P, Sorensen TI, Andersen AN. Socioeconomic disparities in birth weight and body mass index during infancy through age 7 years: a study within the Danish National Birth Cohort. BMJ Open. 2017;7(1):e011781.

    Article  PubMed  PubMed Central  Google Scholar 

  34. 34.

    Smith GD. Learning to live with complexity: ethnicity, socioeconomic position, and health in Britain and the United States. Am J Public Health. 2000;90(11):1694–8.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  35. 35.

    Kim SY, Sharma AJ, Callaghan WM. Gestational diabetes and childhood obesity: what is the link? Curr Opin Obstet Gynecol. 2012;24(6):376–81.

    Article  PubMed  PubMed Central  Google Scholar 

  36. 36.

    Tam WH, Ma RCW, Ozaki R, Li AM, Chan MHM, Yuen LY, Lao TTH, Yang X, Ho CS, Tutino GE, et al. In utero exposure to maternal hyperglycemia increases childhood Cardiometabolic risk in offspring. Diabetes Care. 2017;40(5):679–86.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  37. 37.

    Donovan LE, Cundy T. Does exposure to hyperglycaemia in utero increase the risk of obesity and diabetes in the offspring? A critical reappraisal. Diabet Med. 2015;32(3):295–304.

    Article  PubMed  CAS  Google Scholar 

  38. 38.

    Dabelea D, Hanson RL, Lindsay RS, Pettitt DJ, Imperatore G, Gabir MM, Roumain J, Bennett PH, Knowler WC. Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships. Diabetes. 2000;49(12):2208–11.

    Article  PubMed  CAS  Google Scholar 

  39. 39.

    Puoane T, Tsolekile L, Steyn N. Perceptions about body image and sizes among black African girls living in Cape Town. Ethn Dis. 2010;20(1):29–34.

    PubMed  Google Scholar 

  40. 40.

    Caradas AA, Lambert EV, Charlton KE. An ethnic comparison of eating attitudes and associated body image concerns in adolescent South African schoolgirls. J Hum Nutr Diet. 2001;14(2):111–20.

    Article  PubMed  CAS  Google Scholar 

  41. 41.

    Mehio Sibai A, Nasreddine L, Mokdad AH, Adra N, Tabet M, Hwalla N. Nutrition transition and cardiovascular disease risk factors in Middle East and North Africa countries: reviewing the evidence. Ann Nutr Metab. 2010;57(3–4):193–203.

    Article  PubMed  CAS  Google Scholar 

  42. 42.

    Sattar N, Gill JM. Type 2 diabetes in migrant south Asians: mechanisms, mitigation, and management. Lancet Diabetes Endocrinol. 2015;3(12):1004–16.

    Article  PubMed  Google Scholar 

  43. 43.

    Nightingale CM, Rudnicka AR, Owen CG, Cook DG, Whincup PH. Patterns of body size and adiposity among UK children of south Asian, black African-Caribbean and white European origin: child heart and health study in England (CHASE study). Int J Epidemiol. 2011;40(1):33–44.

    Article  PubMed  Google Scholar 

  44. 44.

    Jenum AK, Diep LM, Holmboe-Ottesen G, Holme IM, Kumar BN, Birkeland KI. Diabetes susceptibility in ethnic minority groups from Turkey, Vietnam, Sri Lanka and Pakistan compared with Norwegians - the association with adiposity is strongest for ethnic minority women. BMC Public Health. 2012;12:150.

    Article  PubMed  PubMed Central  Google Scholar 

  45. 45.

    Consultation WHOE. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004;363(9403):157–63.

    Article  Google Scholar 

  46. 46.

    Krishnaveni GV, Yajnik CS. Developmental origins of diabetes-an Indian perspective. Eur J Clin Nutr. 2017;71:865–9.

  47. 47.

    Hudda MT, Nightingale CM, Donin AS, Owen CG, Rudnicka AR, Wells JCK, Rutter H, Cook DG, Whincup PH. Patterns of childhood body mass index (BMI), overweight and obesity in South Asian and black participants in the English National child measurement programme: effect of applying BMI adjustments standardising for ethnic differences in BMI-body fatness associations. Int J Obes. 2017; https://doi.org/10.1038/ijo.2017.272.

Download references

Acknowledgements

The authors thank all the study participants, H.S. Hatlehol, and the staff at the Child Health Clinics in Stovner, Grorud and Bjerke districts in Oslo. We also thank the other Child Health Clinics in Norway that now are attended by participants who had moved out of their districts of resident at the time of inclusion in this study.

Funding

This study was funded by The Norwegian Research Fund for General Practice (grant number 16/1235). The funding body had no role in designing the study, data collection, data analysis, data interpretation, or in writing the manuscript.

Availability of data and materials

The Regional Committee for Medical and Health Research Ethics for South Eastern Norway and the Norwegian Data approved the conduction of the study. One of the conditions for approval was that strict privacy concerns were respected, the data was stored properly and in line with the Norwegian Law of Privacy Protection, and that data were not made publicly available after participants consented. Public availability would compromise privacy of the respondents. However, provision can be made for inspection of the de-identified data, pending ethical approval from our Ethics committee. For request, please contact Professor and Head of the Stork Groruddalen project, AK Jenum (email: a.k.jenum@medisin.uio.no).

Author information

Affiliations

Authors

Contributions

LS, AKJ and IT conceived and designed the study. IT and LS collected data at the Child Health Clinics and plotted them. IT preformed the statistical analysis supervised by LS and RSF. All authors (IT, AKJ, PL, PBJ, RSF, LF) contributed to interpreting and discussing the results, writing and reviewing the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Ingun Toftemo.

Ethics declarations

Ethics approval and consent to participate

The STORK Groruddalen study was approved by The Regional Committee for Medical and Health Research Ethics for South Eastern Norway, and the Norwegian Data Inspectorate (reference number 2007.894). All participating women gave written consents on behalf of themselves and their offspring, including the collection of prospective growth data from routine Child Health Clinic controls.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Additional file

Additional file 1:

Multinomial logistic regression for child overweight including obesity and thinness, compared to normal weighted at age 4–5 years. Positive BMI adjustments for the South Asian children. (DOCX 26 kb)

Rights and permissions

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Toftemo, I., Jenum, A.K., Lagerløv, P. et al. Contrasting patterns of overweight and thinness among preschool children of different ethnic groups in Norway, and relations with maternal and early life factors. BMC Public Health 18, 1056 (2018). https://doi.org/10.1186/s12889-018-5952-1

Download citation

Keywords

  • Ethnicity
  • Preschool
  • Overweight
  • Obesity
  • Thinness
  • BMI