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Indoor nocturnal noise is associated with body mass index and blood pressure: a cross-sectional study

Abstract

Background

Studies have demonstrated that noise is associated with various health problems, such as obesity and hypertension. Although the evidence of the associations of noise with obesity and hypertension is inconsistent, there seems to be a stronger association of the latter. This study aimed to investigate the associations of noise with body mass index (BMI) and blood pressure in adults living in multi-story residential buildings.

Methods

A cross-sectional study was conducted in Hong Kong from February 2018 to September 2019. The Weinstein Noise Sensitivity Scale, Pittsburgh Sleep Quality Index, ENRICHD Social Support Instrument, Patient Health Questionnaire, Perceived Stress Scale, and Hospital Anxiety and Depression Scale were administered to the participants. BMI and blood pressure were assessed. Nocturnal noise exposure and total sleep duration were measured for a week.

Results

Five hundred adults (66.4% female), with an average age of 39 years (range: 18–80), completed the study. The average levels of nocturnal noise, BMI, systolic blood pressure (SBP), and diastolic blood pressure (DBP) were 51.3 dBA, 22.2 kg/m2, 116.0 mmHg, and 75.4 mmHg, respectively. After adjusting for sociodemographic characteristics, nocturnal noise was associated with BMI (b = 0.54, 95% CI: 0.01 to 1.06, p = 0.045) and SBP (b = 2.90, 95% CI: 1.12 to 4.68, p = 0.001). No association was detected between nocturnal noise and DBP (b = 0.79, 95% CI: − 0.56 to 2.13, p = 0.253). Specifically, higher nocturnal noise was associated with higher BMI (b = 0.72, 95% CI: 0.07 to 1.38, p = 0.031) and SBP (b = 3.91, 95% CI: 2.51 to 5.31, p < 0.001) in females but only higher SBP (b = 3.13, 95% CI: 1.35 to 4.92, p < 0.001) in males. The association between noise and SBP remained significant (b = 2.41, 95% CI: 0.62 to 4.20, p = 0.008) after additionally adjusting for lifestyle, diagnosis of hypertension, psychometric constructs, and sleep.

Conclusions

Indoor nocturnal noise was associated with BMI and blood pressure in females but only blood pressure in males. It is important to control nocturnal noise or use soundproofing materials in buildings to reduce noise exposure.

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Background

In recent decades, environmental noise pollution has gained attention owing to its adverse impacts, such as cardiovascular and metabolic effects on human health [1]. Among noise at different time periods during a day, nocturnal noise has been noted to have the strongest association with health problems [2]. Cardiovascular and metabolic outcomes of noise, e.g., hypertension, ischemic heart diseases, stroke, diabetes, and obesity, have been reported to be associated with noise exposure in some studies, as summarized by Kempen et al. [1]. For instance, an effect of noise (Lnight, outside) on hypertension was proposed to start to occur when the noise level was above 50 dBA [3]. Despite that there was no sufficient evidence of a threshold for the effect of noise on obesity, there might be a threshold around 45–50 dB (Lden) in the association between noise and waist circumference (WC) [4].

Hypertension and obesity are risk factors for cardiovascular disease (CVD), which is the leading cause of death globally [5,6,7]. At least 2.8 million and 17.9 million people die each year due to overweight or obesity and from CVD, respectively [5, 8]. There is a clear link between obesity and hypertension [9,10,11]. Specifically, increases in weight, body mass index (BMI), WC, waist-to-hip ratio (WHR), and waist-to-height ratio were associated with a higher incidence of hypertension [9, 10].

Some other variables have also been identified to play important roles in the association between noise and non-auditory effects. One of them is noise sensitivity. It is suggested that people who are less tolerant of noise are more vulnerable to the negative effects of noise and experience more noise-related health problems [12, 13], and it was noise sensitivity that predicts the non-auditory effects of noise instead of noise level [14]. Moreover, the difference in the impact of noise on human beings has also been detected in specific subgroups, such as in different genders [15]. Additionally, the interaction of noise with lifestyle, such as consumption of alcohol, has also been reported [16].

Furthermore, a major effect of noise on physical health is assumed to be related to sleep [2], which is important in regulating hormonal, glucose, and cardiovascular function [17]. Long-time exposure to noise can cause annoyance and sleep disturbances [2], with these two factors associated with increased activity in the hypothalamic-pituitary-adrenal (HPA) axis [2]. This increased activity leads to the elevation of stress hormones such as cortisol and hence, an imbalance in stress regulation [18, 19]. Elevated cortisol levels are associated with fat accumulation in visceral depots [20], impaired glucose regulation [21], and impact BMI, WC, and blood pressure [22]. A previous study showed that general adiposity, measured by BMI, was associated with an increased death rate [23]. Moreover, there is increasing evidence that both quantitative and qualitative sleep disturbances could result in obesity and hypertension [24,25,26].

The evidence on the effect of noise on blood pressure is inconsistent, and relatively fewer studies analyzed the role of noise on obesity or BMI when compared with hypertension [1]. The WHO Environmental Noise Guidelines have rated the evidence on the association of noise and hypertension as very low due to a response rate of less than 60% reported in many of the studies and the self-reported nature of hypertension measure [1]. Despite that recent studies incorporating cohort studies with moderate quality showed that exposure to noise increased the risk of hypertension, most of the studies were conducted in Europe [27, 28]; focused on aircraft, transportation, or occupational noise; and targeted participants residing in detached, semi-detached, or terraced houses [29]. Moreover, most of the studies have not measured but have estimated or modeled noise levels, which are affected by the bedroom façade, opening of windows, and sound insulation of the house [2]. However, the indoor noise level is determined by multiple factors and not just by outdoor noise, such as traffic noise [30]. In high-density and modern cities such as Hong Kong, most people live in multi-story residential buildings. It was reported that people living in tall buildings experience reverberation noise from activities in adjacent flats in addition to traffic noise, which might be different from European neighborhood environment modeled noise [31]. Moreover, they may also be exposed to sound sources such as public address system and domestic equipment [31]. Recently, a study focused on multi-story residential buildings in Korea, but the noise levels were still estimated rather than measured [29]. Lastly, potential moderators and mediators such as noise sensitivity and sleep were not well studied in a community setting.

Therefore, this study aimed to investigate the effect of nocturnal noise on BMI and blood pressure in Hong Kong Chinese adults residing in urbanized areas. The primary hypothesis was that nocturnal noise was positively associated with BMI and blood pressure. The secondary hypothesis was that noise sensitivity and some lifestyle factors would moderate the associations between noise and BMI as well as blood pressure, while objective sleep parameters and subjective sleep quality would mediate the associations. Moreover, the moderating effects of sociodemographic and lifestyle characteristics were also assessed.

Methods

Design

We carried out this cross-sectional household survey from February 2018 to September 2019 in Hong Kong. First, we obtained a sample list based on the recording from the Hong Kong Census and Statistics Department. All the household address records were organized in quarters and stratified by types of quarters and geographical districts [32]. A random sample of quarters was obtained by applying fixed sampling intervals and non-repetitive random numbers [32]. Every household residing in the selected quarters was covered in the household survey. We mailed the notification letters, which listed the study details, planned visit times, and interviewer identities, to the targeted households before household visits [32]. The interviewer assessed the eligibility criteria during the first household visit. After written informed consent was signed, physical measurements were taken by the interviewer, and the participants were asked to fill in a battery of questionnaires by themselves and to take the nocturnal noise level and objective sleep duration recording for a week. Participants who had completed the survey questionnaires and all the measurements received shopping coupons of HK$300 (approximately US$40) [32].

This study was approved by the Institutional Review Board of the University of Hong Kong/Hospital Authority Hong Kong West Cluster (Reference Number: UW 17–011).

Participants

Adults (aged 18 years and above) who could read and understand Chinese were eligible for recruitment. As only one participant could be recruited per household, in households with two or more eligible subjects, the one with an upcoming birthday was selected. Adults who were deaf, needed hearing aids, took sleeping pills or other medications for sleep disorders or had a psychiatric illness were excluded [32]. Moreover, people were not recruited if they were pregnant, or had children under 2 years of age, or could not complete the nocturnal noise level and objective sleep duration recording [32]. The sample size required, which was calculated based on a rule of thumb of 10 participants per variable, was 210 participants. Furthermore, increases of 0.39 kg/m2 and 0.30 mmHg induced by per 10 dBA increase of noise level were taken for the associations between noise and BMI and systolic blood pressure (SBP), respectively, based on the previous studies [33, 34], with 5% type I error along with a power of 0.8 [35], 351 and 439 participants would be adequate. Lastly, a conservative error of 0.1 on the interaction effect between noise and noise sensitivity was assumed, which yielded a minimum sample size of 396. Therefore, the targeted sample size was 500.

Measurements

General information

We assessed sociodemographic characteristics, including age, sex (Male; Female), marital status (Single; Married/Cohabiting; Separated/Divorced/Widowed), education (Primary school or below; Secondary; Bachelor or above), occupation (Working; Not working; Retired; Students), and family income (from < HK$5000 to > HK$50000) [32]. House type (Multi-story buildings; Townhouse), diagnosis of hypertension (Yes; No), medications taking for hypertension (Yes; No); exercise (from no to 5 h or more/week), smoking (Never; Quit; Yes), and alcohol consumption (Never; Quit; Yes) were also investigated.

Physical measurements

Blood pressure, including SBP and diastolic blood pressure (DBP), was measured using an automatic blood pressure monitor (Model HEM-7111, Omron Healthcare Co., Japan). Blood pressure measurements were taken during the household visit, with the participant in a sitting position and with the right arm at the heart level. The interviewer performed two measurements on each participant at a five-minute interval. A third measurement was conducted after 30 min if any recorded SBP was greater than 140 mmHg or the DBP was greater than 90 mmHg. The final SBP and DBP were calculated by taking the average values of the measurements.

Body height and weight were reported by the participants. BMI was calculated as the individual weight in kilograms divided by the square of height in meters.

Nocturnal noise measurements

The noise dosimeter (Spark 706RC, Larson Davis Inc., US) or the sound level meter (NSRT Mk2, Convergence Instruments, Canada), which was calibrated with CAL150 (Larson Davis Inc., US) at 94 dB sound pressure level, was placed beside the bed in each participant’s bedroom to record the daily nocturnal noise levels from 12 am to 8 am for a week. A-weighted energy equivalence level with 1-min intervals was recorded.

Weinstein noise sensitivity scale (WNSS)

The WNSS, which emphasizes individuals’ affective reactions to noise, was originally designed to measure noise sensitivity [36]. The traditional Chinese WNSS, with 18 items, is reliable and valid to estimate noise sensitivity [37]. All the items were rated from 1 to 6, yielding a total score ranging from 18 to 108. We then standardized the score on a 0–100 scale. Higher total scores indicate greater sensitivity to noise. Cronbach’s alpha of the traditional Chinese WNSS was 0.83 [37].

Total sleep duration

Objective total sleep duration was measured using ActiGraph Link and calculated using Cole-Kripke algorithm with the ActiLife (ActiGraph, US). Total sleep time was the total duration scored as “asleep” [38]. The ActiGraph Link was worn on the non-dominant wrist for seven consecutive days, and records of at least four weekdays and 1 weekend day were considered valid.

Pittsburgh sleep quality index (PSQI)

The 19-item PSQI questionnaire assesses sleep quality in the past month [39]. This index has been widely used among general and clinical populations across countries. The items, each rated on a 0–3 scale, are grouped into seven components. The total scores range from 0 to 21, with a higher score indicating poorer sleep quality [39]. The internal consistency of the traditional Chinese PSQI is satisfactory (Cronbach’s alpha = 0.75).

ENRICHD social support instrument (ESSI)

The traditional Chinese ESSI was used to measure social support. The 6-item scale has a global score from 6 to 30. A higher score denotes a higher level of social support [40]. The traditional Chinese ESSI had a Cronbach’s alpha of 0.79 [40].

Patient health questionnaire (PHQ-15)

The traditional Chinese PHQ-15, which has been validated in the Chinese population, was applied to measure psychosomatic symptoms [41]. It comprises 15 somatic symptoms, and each was rated from 0 (not bothered at all) to 2 (bothered a lot). Cronbach’s alpha of the traditional Chinese PHQ-15 was reported to be 0.79 [41].

Perceived stress scale (PSS)

We administered the traditional Chinese 10-item PSS to evaluate stress levels. The 10-item version, which has two components of stress, showed better validity and reliability than the 14-item and 4-item PSS [42]. Internal consistency, assessed by Cronbach’s alpha of the traditional Chinese 10-item PSS, was 0.85 [42].

Hospital anxiety and depression scale (HADS)

The traditional Chinese HADS was adopted to assess anxiety and depression symptoms. The HADS includes 14 items with non-overlapping 7 items assessing anxiety, and 7 items assessing depression. The anxiety and depression subscales were scored independently, and the total scores of the two subscales were both between 0 and 21. A higher total score denotes more severe anxiety or depression [43]. Values of Cronbach’s alpha for the anxiety and depression subscales were 0.80 and 0.63, respectively [43].

Statistical analysis

Multiple linear regression models with increasing level of covariate adjustment were conducted. Specifically, we first conducted the crude model (Model 1) without any adjustment and Model 2 with adjustment of potential confounders, which included age, gender, education, occupation, income, house type, and marital status. Then, we also conducted Model 3 with additional adjustment for exercise, smoking, alcohol, and BMI (excluded when BMI was the outcome), Model 4 that further adjusted for diagnosis of hypertension (excluded when BMI was the outcome) and the psychometric constructs, and Model 5 that also adjusted for sleep parameters. The analysis was also stratified by gender. To assess the robustness of the results, we also conducted sensitivity analysis by repeating the analysis on people without hypertension, on people without taking antihypertensive medications, and on people living in multi-story buildings. The presence of multicollinearity was assessed using the variance inflation factor (VIF). A VIF > 5 was considered an indication of the presence of multicollinearity [44]. An interaction of noise by sociodemographic and lifestyle characteristics, and noise sensitivity, respectively, was added separately to Model 2 to test the moderating role. An overall p-value was reported if the interaction of noise by categorical variables (marital status, smoking, and alcohol) was tested. We assessed mediators in parallel using the product-of-coefficients method with package “mediation” based on Model 2 [45, 46]. Indirect effects were tested with no strict limitation on the associations of the mediators (sleep duration and sleep quality) with the independent variables and with the dependent variables [47]. The effect of every 10 dBA increase of nocturnal noise was reported. Model adequacy was tested using the normal probability plots and scatter plots of residuals against the predicted values. Estimates were accompanied by 95% confidence intervals (CIs) where appropriate, and 5% nominal level of significance was used in all significance tests. Regression analyses were conducted using RStudio-1.2.1335.

Results

Characteristics

A total of 500 adults participated in this study and completed the assessments. Table 1 shows summary data including sociodemographic, diagnosis of hypertension, lifestyle, nocturnal noise level, BMI, blood pressure, and scale score details. The average patient age was 39.0 years (range: 18–80 years). Overall, 473 participants lived in multi-story buildings, and 27 lived in townhouses.

Table 1 Summary of social-demographic characteristics, nocturnal noise, BMI, blood pressure, and scale scores of the 500 participants

Associations of nocturnal noise with BMI and blood pressure

Unadjusted effects of per 10 dBA increase of nocturnal noise exposure level on BMI, SBP, DBP were 0.61 kg/m2 (95% CI: 0.07 to 1.13, p = 0.025), 3.03 mmHg (95% CI: 1.14 to 4.92, p = 0.002), and 0.68 mmHg (95% CI: − 0.65 to 2.01, p = 0.317), respectively. Table 2 shows that after adjusting for sociodemographic characteristics, nocturnal noise was significantly associated with BMI (b = 0.54, 95% CI: 0.01 to 1.06, p = 0.045) and SBP (b = 2.90, 95% CI: 1.12 to 4.68, p = 0.001). No significant association was detected between nocturnal noise and DBP (b = 0.79, 95% CI: − 0.56 to 2.13, p = 0.253). Nocturnal noise remained to be associated with SBP (b = 2.41, 95% CI: 0.62 to 4.20, p = 0.008), but the associations with BMI (b = 0.50, 95% CI: − 0.03 to 1.03, p = 0.064) and DBP (b = 0.52, 95% CI: − 0.88 to 1.92, p = 0.465) were not statistically significant after additionally adjusting for lifestyle, BMI (excluded when BMI was the outcome), noise sensitivity, somatic symptoms, stress, anxiety, depression, diagnosis of hypertension (excluded when BMI was the outcome), objective total sleep duration, and subjective sleep quality. VIF values for the SBP model ranged from 1.03 to 1.56.

Table 2 Estimated effects of nocturnal noise level from multiple linear regression of BMI, SBP, and DBP in Chinese Adults

Stratified and sensitivity analysis of nocturnal noise on BMI and blood pressure

Table 3 shows the associations of nocturnal noise with BMI, and with blood pressure in different groups. Nocturnal noise was not associated with DBP in all subgroups with p-values greater than 0.171. Every 10 dBA increase in nocturnal noise was associated with 0.72 kg/m2 increase in BMI (95% CI: 0.07 to 1.38, p = 0.031) and 3.91 mmHg increase in SBP (95% CI: 2.51 to 5.31, p < 0.001) in females and 3.13 mmHg increase in SBP (95% CI: 1.35 to 4.92, p < 0.001) in males. Moreover, for people without diagnosis of hypertension, without taking medication for hypertension, living in the multi-story buildings, every 10 dBA increase in nocturnal noise was significantly associated with 3.54 mmHg (95% CI: 2.40 to 4.67, p < 0.001), 3.58 mmHg (95% CI: 0.75 to 4.39, p < 0.001), and 3.01 mmHg (95% CI: 1.20 to 4.82, p = 0.001) increase in SBP, respectively.

Table 3 Stratified and sensitivity analysis on the associations between nocturnal noise level and BMI, SBP and DBP

Moderating effects of sociodemographic, lifestyle, and noise sensitivity on the associations between noise and BMI and blood pressure

We assessed the moderating effects of sociodemographic, lifestyle, and noise sensitivity on BMI, SBP, or DBP. Only the moderation of noise by age (b = 0.01, 95% CI: 0.00, 0.02, p = 0.009) was observed (Table 4). The p-value for the interaction between noise and noise sensitivity on DBP was 0.056.

Table 4 Moderating effects of sociodemographic and lifestyle variables and noise sensitivity on nocturnal noise level

Mediating effects of sleep parameters on the associations between noise with BMI and blood pressure

The indirect effects of sleep duration on the associations between noise and BMI, SBP, and DBP were 0.02 (95% CI: − 0.06, 0.01, p = 0.602), 0.15 (95% CI: − 0.08, 0.50, p = 0.240), and 0.04 (95% CI: − 0.15, 0.30, p = 0.680), respectively.

The indirect effects of sleep quality on the associations between noise and BMI, SBP and DBP were − 0.02 (95% CI: − 0.08, 0.00, p = 0.382), − 0.02 (95% CI: − 0.19, 0.10, p = 0.830), and − 0.04 (95% CI: − 0.19, 0.00, p = 0.470), respectively.

Discussion

To the best of our knowledge, this is the first study to investigate the relationships of nocturnal noise level with BMI and with blood pressure in community-dwelling Chinese adults living in multi-story buildings. We demonstrated that an increase in nocturnal noise exposure measured over one week was associated with higher BMI and blood pressure in the daytime.

Previous studies showed that an increase in exposure to modeled noise levels was significantly associated with higher BMI and WC and a higher risk of obesity [33, 48]. However, Pyko et al. [49] did not find an association between road traffic noise and BMI, but the association with WC as well as central obesity was significant. The effect of noise on obesity was hypothesized through stress response with the activation of the HPA axis, which could lead to increased levels of stress hormones such as cortisol [19, 50]. Alterations in cortisol levels are related to metabolic changes, including weight gain [51]. The association between noise and BMI was only found in females in this study. In an earlier study, an association between noise and obesity was found in women who were highly sensitive to noise [48]. Specifically, every 10 dB increase in road traffic noise was associated with 0.02 and 0.01 units increase in BMI and WC, respectively, and an odds ratio of 1.24 for WHR ≥ 0.85 in highly noise-sensitive women [48]. We posited that females might be more annoyed by noise than males [52]. Therefore, future studies incorporating noise annoyance or other reactions and emotions to noise are desirable to understand the underlying mechanism.

Although the relationship between noise exposure and blood pressure has been extensively investigated, the results, to date, are still inconsistent. Concerning the association between transportation noise and the prevalence of hypertension, the relative risks (RRs) per 10 dBA of road traffic noise, aircraft noise, and rail traffic noise were all approximately 1.05 [1]. However, some studies failed to find the significant associations between noise and blood pressure in specific population groups such as general women [53] and pregnant women [54]. The inconsistencies may result from the sample sizes, self-reported high blood pressure diagnosis, accurate exposure levels of noise, and other potential confounding factors. This study demonstrated the significant association between noise and SBP using measured noise levels and measured blood pressure after adjusting for various confounding factors. This result was consistent with some earlier studies [55, 56]. Moreover, this study revealed that the association between noise and SBP was stronger in females than in males, which was in line with a previous cohort study of 701,174 residents [57]. It also demonstrated no statistically significant association between noise and DBP, which was consistent with one previous study [34]. The associations remained similar when excluding people with hypertension or who were taking medications for hypertension. The difference between the associations of noise with SBP and with DBP might be due to that SBP was more sensitive to noise level [58]. Furthermore, there could be a threshold noise level for DBP [59]. When individuals were exposed to a level lower than 80 dB, DBP did not show a significant increase [60]. The mean nocturnal noise level in this study was around 51 dBA which might be relatively low to cause a significant increase in DBP. On the contrary, a significant association was also reported [29]. Standardized acoustic stressors and time-dependent analysis might be vital for interpreting the association [58]. Therefore, the inconsistent results call for more precise and professional research. Nevertheless, the association between SBP and the risk of CVD calls for the control of potential risk factors [61].

Although the impact of noise on human beings has been found in some specific groups such as females, people who drink alcohol, and highly noise-sensitive people [15, 16, 48], this study did not find any moderating effects of sociodemographic and lifestyle variables, and noise sensitivity, except for the moderating effect of aging on the association between noise and DBP. For the insignificant associations, it might be due to the difference between acute noise and chronic noise and the threshold of the noise level. Nevertheless, the impact of noise on DBP increases as people aging. The previous study indicated that the impact of noise could and should be differentiated between various groups such as children and the elderly [62]. Age might moderate the vulnerability to noise on specific health outcomes given specific groups. It was reported that isolated diastolic hypertension was more common in middle-aged groups in the Chinese population [63]. The mean age of the sample in this study was 39 years, and the middle-aged participants occupied around 50% of the sample. We proposed that age might also moderate the effect of noise on SBP, and a sample incorporating more elderly would be of interest due to the characteristics of systolic blood pressure. Therefore, attention needs to be paid to the effect of age and clarify the possible associations and mechanisms.

It has been hypothesized that noise may affect cardiovascular and metabolic functions through sleep disturbance, where sleep plays a significant role in modulating hormonal release [49]. However, neither objective sleep parameter nor subjective sleep parameter was identified as the mediator in the association between noise and blood pressure or BMI. The effect of noise on hypertension has been hypothesized to be through the activation of the HPA axis [50]. Sleep deprivation is associated with the activation of the HPA axis [64]. Sleep restriction was shown to be associated with increased sympathetic activity and venous endothelial dysfunction [65]. Hence, people who have sleep disturbance have higher risks of hypertension. In terms of BMI, previous studies have indicated that lack of sleep increases appetite and reduces energy expenditure by affecting serum levels of leptin and ghrelin, thus increasing the risk of being overweight and obese [66]. The dysregulation of “hunger hormones” due to the anorexigenic hormone leptin levels resulting from sleep disturbances may induce increased food intake [67]. Sleep deprivation may lead to reduced energy expenditure through altered thermoregulation and increased fatigue [68]. Hence, the risk of being overweight and obese increases. Nonetheless, important factors such as diet were not investigated in this study. Therefore, future studies cover more sleep parameters and confounding factors are needed to verify how sleep affects the relationship between noise and health problems.

This study used a noise dosimeter to record nocturnal noise levels for a week, which was much more precise than the estimated noise levels used previously. Furthermore, both subjective sleep and objective sleep parameters were included. In addition, noise sensitivity, considered to affect vulnerability, was studied.

However, several limitations are worth noting. First, body weight and height measurements were self-reported by the participants, which might have led to imprecision. WC and laboratory indicators of obesity could also be good indices. Second, we did not include eating habits in this study, yet we were evaluating effects on BMI. Third, blood pressure was not measured at the same time in the participants, which might have affected the results. However, these might not be very feasible in a community setting. The time of blood pressure measurements needs to be recorded in the future, and any differences in neighborhood noise from other noise sources need to be noted. Fourth, future studies need to include the family history of hypertension, considering its predictive role in blood pressure and obesity [69]. Fifth, this study only measured A-weighted sound levels. Future studies including more characteristics such as frequency and variations are desirable [70, 71]. Lastly, the sample power might not be large enough to examine certain effects, such as the interaction, and studies with a larger sample size are of interest.

Conclusions

In this study, higher nocturnal noise was associated with higher BMI and SBP, while no statistically significant relationship between noise and DBP was observed. However, the association between noise and BMI was only found in females. The impact of noise pollution on health calls for further study, and controlling nocturnal noise level by using soundproofing materials, noise cancellation devices, or earplugs may contribute to a reduction of related health risks.

Availability of data and materials

The datasets generated and/or analyzed during the current study are not publicly available due to confidentiality. The data access needs approval from the institutional and ethics committee.

Abbreviations

BMI:

Body mass index

CI:

Confidence interval

CVD:

Cardiovascular disease

DBP:

Diastolic blood pressure

HADS:

Hospital Anxiety and Depression Scale

HPA:

Hypothalamic-pituitary-adrenal

PHQ-15:

Patient Health Questionnaire

PSQI:

Pittsburgh Sleep Quality Index

PSS:

Perceived Stress Scale

RR:

Relative risk

SBP:

Systolic blood pressure

VIF:

Variance inflation factor

WC:

Waist circumference

WNSS:

Weinstein Noise Sensitivity Scale

References

  1. Kempen EV, Casas M, Pershagen G, Foraster M. WHO environmental noise guidelines for the European region: a systematic review on environmental noise and cardiovascular and metabolic effects: a summary. Int J Environ Res Public Health. 2018;15(2):379. https://doi.org/10.3390/ijerph15020379.

    Article  PubMed Central  Google Scholar 

  2. Munzel T, Gori T, Babisch W, Basner M. Cardiovascular effects of environmental noise exposure. Eur Heart J. 2014;35(13):829–36. https://doi.org/10.1093/eurheartj/ehu030.

    Article  PubMed  PubMed Central  Google Scholar 

  3. World Health Organization Regional Office for Europe. Night noise guidelines for Europe. 2009. Retrieved from https://www.euro.who.int/__data/assets/pdf_file/0017/43316/E92845.pdf. Accessed 7 Aug 2020.

  4. Pyko A, Eriksson C, Lind T, Mitkovskaya N, Wallas A, Ögren M, et al. Long-term exposure to transportation noise in relation to development of obesity—a cohort study. Environ Health Perspect. 2017;125(11):117005. https://doi.org/10.1289/EHP1910.

    Article  PubMed  PubMed Central  Google Scholar 

  5. World Health Organization. Cardiovascular diseases. 2019. Retrieved from https://www.who.int/health-topics/cardiovascular-diseases/#tab=tab_1. Accessed 7 Aug 2020.

  6. Kjeldsen SE. Hypertension and cardiovascular risk: general aspects. Pharmacol Res. 2018;129:95–9. https://doi.org/10.1016/j.phrs.2017.11.003.

    Article  PubMed  Google Scholar 

  7. World Health Organization. Obesity and overweight. 2020. Retrieved from https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight. Accessed 7 Aug 2020.

  8. World Health Organization. 10 facts on obesity. 2017. Retrieved from https://www.who.int/features/factfiles/obesity/en/. Accessed 7 Aug 2020.

  9. Jayedi A, Rashidy-Pour A, Khorshidi M, Shab-Bidar S. Body mass index, abdominal adiposity, weight gain and risk of developing hypertension: a systematic review and dose-response meta-analysis of more than 2.3 million participants. Obes Rev. 2018;19(5):654–67. https://doi.org/10.1111/obr.12656.

    Article  CAS  PubMed  Google Scholar 

  10. Momin M, Fan F, Li J, Jia J, Zhang L, Zhang Y, et al. Joint effects of body mass index and waist circumference on the incidence of hypertension in a community-based Chinese population. Obes Facts. 2020;13(2):245–55. https://doi.org/10.1159/000506689.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Jiang SZ, Lu W, Zong XF, Ruan HY, Liu Y. Obesity and hypertension. Exp Ther Med. 2016;12(4):2395–9. https://doi.org/10.3892/etm.2016.3667.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Hill E, Billington R, Krägeloh C. Noise sensitivity and diminished health: testing moderators and mediators of the relationship. Noise Health. 2014;16(68):47–56. https://doi.org/10.4103/1463-1741.127855.

    Article  PubMed  Google Scholar 

  13. Kishikawa H, Matsui T, Uchiyama I, Miyakawa M, Hiramatsu K, Stansfeld S. Noise sensitivity and subjective health: questionnaire study conducted along trunk roads in Kusatsu, Japan. Noise Health. 2009;11(43):111–7. https://doi.org/10.4103/1463-1741.50696.

    Article  PubMed  Google Scholar 

  14. Park J, Chung S, Lee J, Sung JH, Cho SW, Sim CS. Noise sensitivity, rather than noise level, predicts the non-auditory effects of noise in community samples: a population-based survey. BMC Public Health. 2017;17(1):315. https://doi.org/10.1186/s12889-017-4244-5.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Gulian E, Thomas JR. The effects of noise, cognitive set and gender on mental arithmetic performance. Br J Psychol. 1986;77(4):503–11. https://doi.org/10.1111/j.2044-8295.1986.tb02214.x.

    Article  Google Scholar 

  16. Colquhaun WP. Interaction of noise with alcohol on a task of sustained attention. J Occup Environ Med. 1977;19(8):574.

    Google Scholar 

  17. Van Cauter E, Spiegel K, Tasali E, Leproult R. Metabolic consequences of sleep and sleep loss. Sleep Med. 2008;9(Suppl 1):S23–8. https://doi.org/10.1016/S1389-9457(08)70013-3.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Munzel T, Sorensen M, Schmidt F, Schmidt E, Steven S, Kroller-Schon S, et al. The adverse effects of environmental noise exposure on oxidative stress and cardiovascular risk. Antioxid Redox Signal. 2018;28(9):873–908. https://doi.org/10.1089/ars.2017.7118.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Ising H, Braun C. Acute and chronic endocrine effects of noise: review of the research conducted at the institute for water, soil and air hygiene. Noise Health. 2000;2(7):7–24.

    PubMed  Google Scholar 

  20. Anagnostis P, Athyros VG, Tziomalos K, Karagiannis A, Mikhailidis DP. Clinical review: the pathogenetic role of cortisol in the metabolic syndrome: a hypothesis. J Clin Endocrinol Metab. 2009;94(8):2692–701. https://doi.org/10.1210/jc.2009-0370.

    Article  CAS  PubMed  Google Scholar 

  21. Rosmond R. Stress induced disturbances of the HPA axis: a pathway to type 2 diabetes? Med Sci Monit. 2003;9(2):RA35–9.

    PubMed  Google Scholar 

  22. Abraham SB, Rubino D, Sinaii N, Ramsey S, Nieman LK. Cortisol, obesity, and the metabolic syndrome: a cross-sectional study of obese subjects and review of the literature. Obesity (Silver Spring). 2013;21(1):E105–17. https://doi.org/10.1002/oby.20083.

    Article  CAS  Google Scholar 

  23. Pischon T, Boeing H, Hoffmann K, Bergmann M, Schulze MB, Overvad K, et al. General and abdominal adiposity and risk of death in Europe. N Engl J Med. 2008;359(20):2105–20. https://doi.org/10.1056/NEJMoa0801891.

    Article  CAS  PubMed  Google Scholar 

  24. Krističević T, Štefan L, Sporiš G. The associations between sleep duration and sleep quality with body-mass index in a large sample of young adults. Int J Environ Res Public Health. 2018;15(4):758. https://doi.org/10.3390/ijerph15040758.

    Article  PubMed Central  Google Scholar 

  25. Grandner M, Mullington JM, Hashmi SD, Redeker NS, Watson NF, Morgenthaler TI. Sleep duration and hypertension: analysis of > 700,000 adults by age and sex. J Clin Sleep Med. 2018;14(6):1031–9. https://doi.org/10.5664/jcsm.7176.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Zhang H, Li Y, Zhao X, Mao Z, Abdulai T, Liu X, et al. The association between PSQI score and hypertension in a Chinese rural population: the Henan rural cohort study. Sleep Med. 2019;58:27–34. https://doi.org/10.1016/j.sleep.2019.03.001.

    Article  PubMed  Google Scholar 

  27. Chen F, Fu W, Shi O, Li D, Jiang Q, Wang T, et al. Impact of exposure to noise on the risk of hypertension: a systematic review and meta-analysis of cohort studies. Environ Res. 2021;195:110813. https://doi.org/10.1016/j.envres.2021.110813.

    Article  CAS  PubMed  Google Scholar 

  28. Dzhambov AM, Dimitrova DD. Residential road traffic noise as a risk factor for hypertension in adults: systematic review and meta-analysis of analytic studies published in the period 2011-2017. Environ Pollut. 2018;240:306–18. https://doi.org/10.1016/j.envpol.2018.04.122.

    Article  CAS  PubMed  Google Scholar 

  29. Lee PJ, Park SH, Jeong JH, Choung T, Kim KY. Association between transportation noise and blood pressure in adults living in multi-storey residential buildings. Environ Int. 2019;132:105101. https://doi.org/10.1016/j.envint.2019.105101.

    Article  PubMed  Google Scholar 

  30. Locher B, Piquerez A, Habermacher M, Ragettli M, Roosli M, Brink M, et al. Differences between outdoor and indoor sound levels for open, tilted, and closed windows. Int J Environ Res Public Health. 2018;15(1):149. https://doi.org/10.3390/ijerph15010149.

    Article  PubMed Central  Google Scholar 

  31. Park SH, Lee PJ, Lee BK. Levels and sources of neighbour noise in heavyweight residential buildings in Korea. Appl Acoust. 2017;120:148–57. https://doi.org/10.1016/j.apacoust.2017.01.012.

    Article  Google Scholar 

  32. Li S, Fong DYT, Wong JYH, McPherson B, Lau EYY, Huang L, et al. Noise sensitivity associated with nonrestorative sleep in Chinese adults: a cross-sectional study. BMC Public Health. 2021;21(1):643. https://doi.org/10.1186/s12889-021-10667-2.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Foraster M, Eze IC, Vienneau D, Schaffner E, Jeong A, Heritier H, et al. Long-term exposure to transportation noise and its association with adiposity markers and development of obesity. Environ Int. 2018;121(Pt 1):879–89. https://doi.org/10.1016/j.envint.2018.09.057.

    Article  PubMed  Google Scholar 

  34. Sørensen M, Hvidberg M, Hoffmann B, Andersen ZJ, Nordsborg RB, Lillelund KG, et al. Exposure to road traffic and railway noise and associations with blood pressure and self-reported hypertension: a cohort study. Environ Health. 2011;10(1):92. https://doi.org/10.1186/1476-069X-10-92.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Hsieh FY, Bloch DA, Larsen MD. A simple method of sample size calculation for linear and logistic regression. Stat Med. 1998;17(14):1623–34. https://doi.org/10.1002/(SICI)1097-0258(19980730)17:14<1623::AID-SIM871>3.0.CO;2-S.

    Article  CAS  PubMed  Google Scholar 

  36. Weinstein ND. Individual differences in reactions to noise: a longitudinal study in a college dormitory. J Appl Psychol. 1978;63(4):458–66. https://doi.org/10.1037/0021-9010.63.4.458.

    Article  CAS  PubMed  Google Scholar 

  37. Fong DYT, Takemura N, Chau PH, Wan SLY, Wong JYH. Measurement properties of the Chinese Weinstein noise sensitivity scale. Noise Health. 2017;19(89):193–9. https://doi.org/10.4103/nah.NAH_110_16.

    Article  PubMed  PubMed Central  Google Scholar 

  38. ActiGraph. ActiLife 6 user’s manual. Retrieved from: https://s3.amazonaws.com/actigraphcorp.com/wp-content/uploads/2018/02/22094137/SFT12DOC13-ActiLife-6-Users-Manual-Rev-A-110315.pdf. Accessed 30 Sept 2017.

  39. Chong AML, Cheung CK. Factor structure of a Cantonese-version Pittsburgh sleep quality index. Sleep Biol Rhythms. 2012;10(2):118–25. https://doi.org/10.1111/j.1479-8425.2011.00532.x.

    Article  Google Scholar 

  40. Mak WWS, Cheung RYM, Law LSC. Sense of community in Hong Kong: relations with community-level characteristics and residents’ well-being. Am J Community Psychol. 2009;44(1-2):80–92. https://doi.org/10.1007/s10464-009-9242-z.

    Article  PubMed  Google Scholar 

  41. Lee S, Ma YL, Tsang A. Psychometric properties of the Chinese 15-item patient health questionnaire in the general population of Hong Kong. J Psychosom Res. 2011;71(2):69–73. https://doi.org/10.1016/j.jpsychores.2011.01.016.

    Article  PubMed  Google Scholar 

  42. Leung DY, Lam TH, Chan SS. Three versions of perceived stress scale: validation in a sample of Chinese cardiac patients who smoke. BMC Public Health. 2010;10(1):513. https://doi.org/10.1186/1471-2458-10-513.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Chan YF, Leung DY, Fong DY, Leung CM, Lee AM. Psychometric evaluation of the hospital anxiety and depression scale in a large community sample of adolescents in Hong Kong. Qual Life Res. 2010;19(6):865–73. https://doi.org/10.1007/s11136-010-9645-1.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Daoud JI. Multicollinearity and regression analysis. Journal of Physics Conference, Series. 2017;949(1):012009.

    Article  Google Scholar 

  45. Imai K, Keele L, Tingley D. A general approach to causal mediation analysis. Psychol Methods. 2010;15(4):309–34. https://doi.org/10.1037/a0020761.

    Article  PubMed  Google Scholar 

  46. Tingley D, Yamamoto T, Hirose K, Keele L, Imai K. Mediation: r package for causal mediation analysis. J Stat Softw. 2014;59(5):1–38.

    Article  Google Scholar 

  47. Hayes AF, Rockwood NJ. Regression-based statistical mediation and moderation analysis in clinical research: observations, recommendations, and implementation. Behav Res Ther. 2017;98:39–57. https://doi.org/10.1016/j.brat.2016.11.001.

    Article  PubMed  Google Scholar 

  48. Oftedal B, Krog NH, Pyko A, Eriksson C, Graff-Iversen S, Haugen M, et al. Road traffic noise and markers of obesity - a population-based study. Environ Res. 2015;138:144–53. https://doi.org/10.1016/j.envres.2015.01.011.

    Article  CAS  PubMed  Google Scholar 

  49. Pyko A, Eriksson C, Oftedal B, Hilding A, Ostenson CG, Krog NH, et al. Exposure to traffic noise and markers of obesity. Occup Environ Med. 2015;72(8):594–601. https://doi.org/10.1136/oemed-2014-102516.

    Article  PubMed  Google Scholar 

  50. Christensen JS, Raaschou-Nielsen O, Tjonneland A, Overvad K, Nordsborg RB, Ketzel M, et al. Road traffic and railway noise exposures and adiposity in adults: a cross-sectional analysis of the Danish diet, Cancer, and health cohort. Environ Health Perspect. 2016;124(3):329–35. https://doi.org/10.1289/ehp.1409052.

    Article  CAS  PubMed  Google Scholar 

  51. Vicennati V, Pasqui F, Cavazza C, Pagotto U, Pasquali R. Stress-related development of obesity and cortisol in women. Obesity (Silver Spring). 2009;17(9):1678–83. https://doi.org/10.1038/oby.2009.76.

    Article  CAS  Google Scholar 

  52. Beheshti MH, Taban E, Samaei SE, Faridan M, Khajehnasiri F, Khaveh LT, et al. The influence of personality traits and gender on noise annoyance in laboratory studies. Personal Individ Differ. 2019;148:95–100. https://doi.org/10.1016/j.paid.2019.05.027.

    Article  Google Scholar 

  53. Evrard AS, Lefevre M, Champelovier P, Lambert J, Laumon B. Does aircraft noise exposure increase the risk of hypertension in the population living near airports in France? Occup Environ Med. 2017;74(2):123–9. https://doi.org/10.1136/oemed-2016-103648.

    Article  PubMed  Google Scholar 

  54. Sears CG, Braun JM, Ryan PH, Xu Y, Werner EF, Lanphear BP, et al. The association of traffic-related air and noise pollution with maternal blood pressure and hypertensive disorders of pregnancy in the HOME study cohort. Environ Int. 2018;121(Pt 1):574–81. https://doi.org/10.1016/j.envint.2018.09.049.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  55. Lee JH, Kang W, Yaang SR, Choy N, Lee CR. Cohort study for the effect of chronic noise exposure on blood pressure among male workers in Busan. Korea Am J Ind Med. 2009;52(6):509–17. https://doi.org/10.1002/ajim.20692.

    Article  PubMed  Google Scholar 

  56. Ismaila SO, Odusote A. Noise exposure as a factor in the increase of blood pressure of workers in a sack manufacturing industry. Beni-Suef Univ J Basic Appl Sci. 2014;3(2):116–21. https://doi.org/10.1016/j.bjbas.2014.05.004.

    Article  Google Scholar 

  57. Shin S, Bai L, Oiamo TH, Burnett RT, Weichenthal S, Jerrett M, et al. Association between road traffic noise and incidence of diabetes mellitus and hypertension in Toronto, Canada: a population-based cohort study. J Am Heart Assoc. 2020;9(6):e013021. https://doi.org/10.1161/JAHA.119.013021.

    Article  PubMed  PubMed Central  Google Scholar 

  58. Germano G, Damiani S, Milito U, Germano U, Giarrizzo C, Santucci A. Noise stimulus in normal subjects: time-dependent blood pressure pattern assessment. Clin Cardiol. 1991;14(4):321–5. https://doi.org/10.1002/clc.4960140408.

    Article  CAS  PubMed  Google Scholar 

  59. Talbott EO, Gibson LB, Burks A, Engberg R, McHugh KP. Evidence for a dose-response relationship between occupational noise and blood pressure. Arch Environ Health. 1999;54(2):71–8. https://doi.org/10.1080/00039899909602239.

    Article  CAS  PubMed  Google Scholar 

  60. Fogari R, Zoppi A, Vanasia A, Marasi G, Villa G. Occupational noise exposure and blood pressure. J Hypertens. 1994;12(4):475–9.

    Article  CAS  PubMed  Google Scholar 

  61. Tin LL, Beevers DG, Lip GY. Systolic vs diastolic blood pressure and the burden of hypertension. J Hum Hypertens. 2002;16(3):147–50. https://doi.org/10.1038/sj.jhh.1001373.

    Article  CAS  PubMed  Google Scholar 

  62. van Kamp I, Davies H. Noise and health in vulnerable groups: a review. Noise Health. 2013;15(64):153–9. https://doi.org/10.4103/1463-1741.112361.

    Article  PubMed  Google Scholar 

  63. Mahajan S, Zhang D, He S, Lu Y, Gupta A, Spatz ES, et al. Prevalence, awareness, and treatment of isolated diastolic hypertension: insights from the China PEACE million persons project. J Am Heart Assoc. 2019;8(19):e012954. https://doi.org/10.1161/JAHA.119.012954.

    Article  PubMed  PubMed Central  Google Scholar 

  64. Buckley TM, Schatzberg AF. On the interactions of the hypothalamic-pituitary-adrenal (HPA) axis and sleep: normal HPA axis activity and circadian rhythm, exemplary sleep disorders. J Clin Endocrinol Metab. 2005;90(5):3106–14. https://doi.org/10.1210/jc.2004-1056.

    Article  CAS  PubMed  Google Scholar 

  65. Dettoni JL, Consolim-Colombo FM, Drager LF, Rubira MC, Souza SB, Irigoyen MC, et al. Cardiovascular effects of partial sleep deprivation in healthy volunteers. J Appl Physiol (1985). 2012;113(2):232–6.

    Article  CAS  Google Scholar 

  66. Taheri S, Lin L, Austin D, Young T, Mignot E. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 2004;1(3):e62. https://doi.org/10.1371/journal.pmed.0010062.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  67. Reutrakul S, Van Cauter E. Sleep influences on obesity, insulin resistance, and risk of type 2 diabetes. Metabolism. 2018;84:56–66. https://doi.org/10.1016/j.metabol.2018.02.010.

    Article  CAS  PubMed  Google Scholar 

  68. Patel SR, Hu FB. Short sleep duration and weight gain: a systematic review. Obesity (Silver Spring). 2008;16(3):643–53. https://doi.org/10.1038/oby.2007.118.

    Article  Google Scholar 

  69. Ranasinghe P, Cooray DN, Jayawardena R, Katulanda P. The influence of family history of hypertension on disease prevalence and associated metabolic risk factors among Sri Lankan adults. BMC Public Health. 2015;15(1):576. https://doi.org/10.1186/s12889-015-1927-7.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Khosravipour M, Khosravi F, Ashtarian H, Rezaei M, Moradi Z, Mohammadi SH. The effects of exposure to different noise frequency patterns on blood pressure components and hypertension. Int Arch Occup Environ Health. 2020;93(8):975–82. https://doi.org/10.1007/s00420-020-01545-2.

    Article  PubMed  Google Scholar 

  71. Konkani A, Oakley B, Penprase B. Reducing hospital ICU noise: a behavior-based approach. J Healthc Eng. 2014;5(2):229–46. https://doi.org/10.1260/2040-2295.5.2.229.

    Article  PubMed  Google Scholar 

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Acknowledgments

We acknowledge the contributions of all the research assistants for supporting data collection.

Funding

This study was supported by the Health and Medical Research Fund [Grant No. 14150801], the Food and Health Bureau, Hong Kong Special Administrative Region. The funder was not involved in the study’s design, the collection, analysis, and interpretation of the data, or the preparation of the manuscript.

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SL was involved in the data collection, analysis interpretation, and manuscript preparation and revisions. DYTF designed the study and revised the manuscript critically for important intellectual content. JYHW, BM, EYY, LH, and MSMI made important contributions to the application of grant and revision of the manuscript. All authors read and approved the final manuscript.

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Correspondence to Daniel Yee Tak Fong.

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This study was approved by the Institutional Review Board of the University of Hong Kong/Hospital Authority Hong Kong West Cluster (Reference Number: UW 17–011). Each participant included in the study gave the written informed consent.

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Li, S., Fong, D.Y.T., Wong, J.Y.H. et al. Indoor nocturnal noise is associated with body mass index and blood pressure: a cross-sectional study. BMC Public Health 21, 815 (2021). https://doi.org/10.1186/s12889-021-10845-2

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