Francis ME, Eggers PW, Hostetter TH, Briggs JP: Association between serum homocysteine and markers of impaired kidney function in adults in the United States.[see comment]. Kidney International. 2004, 66: 303-312. 10.1111/j.1523-1755.2004.00732.x.
Article
CAS
PubMed
Google Scholar
Hoogeveen EK, Kostense PJ, Jakobs C, Dekker JM, Nijpels G, Heine RJ, et al: Hyperhomocysteinemia increases risk of death, especially in type 2 diabetes: 5-year follow-up of the Hoorn Study. Circulation. 2000, 101: 1506-1511.
Article
CAS
PubMed
Google Scholar
Humphrey LL, Fu R, Rogers K, Freeman M, Helfand M: Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis. Mayo Clin Proc. 2008, 83: 1203-1212. 10.4065/83.11.1203.
Article
PubMed
Google Scholar
Winkelmayer WC, Kramar R, Curhan GC, Chandraker A, Endler G, Fodinger M, et al: Fasting plasma total homocysteine levels and mortality and allograft loss in kidney transplant recipients: a prospective study. J Am Soc Nephrol. 2005, 16: 255-260.
Article
CAS
PubMed
Google Scholar
Refsum H, Nurk E, Smith AD, Ueland PM, Gjesdal CG, Bjelland I, et al: The Hordaland Homocysteine Study: a community-based study of homocysteine, its determinants, and associations with disease. J Nutr. 2006, 136: 1731S-1740S.
CAS
PubMed
Google Scholar
Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, et al: Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Hypertension. 2003, 42: 1050-1065. 10.1161/01.HYP.0000102971.85504.7c.
Article
CAS
PubMed
Google Scholar
Foley RN, Parfrey PS, Sarnak MJ: Clinical epidemiology of cardiovascular disease in chronic renal disease. Am J Kidney Dis. 1998, 32: S112-S119. 10.1053/ajkd.1998.v32.pm9820470.
Article
CAS
PubMed
Google Scholar
Upchurch GR, Welch GN, Fabian AJ, Freedman JE, Johnson JL, Keaney JF, et al: Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase. J Biol Chem. 1997, 272: 17012-17017. 10.1074/jbc.272.27.17012.
Article
CAS
PubMed
Google Scholar
Welch GN, Loscalzo J: Homocysteine and atherothrombosis. N Engl J Med. 1998, 338: 1042-1050. 10.1056/NEJM199804093381507.
Article
CAS
PubMed
Google Scholar
Hoogeveen EK, Kostense PJ, Jager A, Heine RJ, Jakobs C, Bouter LM, et al: Serum homocysteine level and protein intake are related to risk of microalbuminuria: the Hoorn Study. Kidney Int. 1998, 54: 203-209. 10.1038/sj.ki.4495353.
Article
CAS
PubMed
Google Scholar
Jager A, Kostense PJ, Nijpels G, Dekker JM, Heine RJ, Bouter LM, et al: Serum homocysteine levels are associated with the development of (micro)albuminuria: the Hoorn study. Arterioscler Thromb Vasc Biol. 2001, 21: 74-81. 10.1161/01.ATV.21.1.74.
Article
CAS
PubMed
Google Scholar
Chico A, Perez A, Cordoba A, Arcelus R, Carreras G, de LA, et al: Plasma homocysteine is related to albumin excretion rate in patients with diabetes mellitus: a new link between diabetic nephropathy and cardiovascular disease?. Diabetologia. 1998, 41: 684-693. 10.1007/s001250050969.
Article
CAS
PubMed
Google Scholar
Lanfredini M, Fiorina P, Peca MG, Veronelli A, Mello A, Astorri E, et al: Fasting and post-methionine load homocyst(e)ine values are correlated with microalbuminuria and could contribute to worsening vascular damage in non-insulin-dependent diabetes mellitus patients. Metabolism. 1998, 47: 915-921. 10.1016/S0026-0495(98)90344-4.
Article
CAS
PubMed
Google Scholar
Keane WF, Eknoyan G: Proteinuria, albuminuria, risk, assessment, detection, elimination (PARADE): a position paper of the National Kidney Foundation. Am J Kidney Dis. 1999, 33: 1004-1010. 10.1016/S0272-6386(99)70442-7.
Article
CAS
PubMed
Google Scholar
Viberti GC, Hill RD, Jarrett RJ, Argyropoulos A, Mahmud U, Keen H: Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus. Lancet. 1982, 1: 1430-1432.
Article
CAS
PubMed
Google Scholar
Yuyun MF, Khaw KT, Luben R, Welch A, Bingham S, Day NE, et al: Microalbuminuria independently predicts all-cause and cardiovascular mortality in a British population: The European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. Int J Epidemiol. 2004, 33: 189-198. 10.1093/ije/dyh008.
Article
PubMed
Google Scholar
Obermayr RP, Temml C, Gutjahr G, Knechtelsdorfer M, Oberbauer R, Klauser-Braun R: Elevated uric acid increases the risk for kidney disease. J Am Soc Nephrol. 2008, 19: 2407-2413. 10.1681/ASN.2008010080.
Article
PubMed
PubMed Central
Google Scholar
Madero M, Sarnak MJ, Wang X, Greene T, Beck GJ, Kusek JW, et al: Uric acid and long-term outcomes in CKD. Am J Kidney Dis. 2009, 53: 796-803. 10.1053/j.ajkd.2008.12.021.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lussier-Cacan S, Xhignesse M, Piolot A, Selhub J, Davignon J, Genest J: Plasma total homocysteine in healthy subjects: sex-specific relation with biological traits. Am J Clin Nutr. 1996, 64: 587-593.
CAS
PubMed
Google Scholar
Malinow MR, Levenson J, Giral P, Nieto FJ, Razavian M, Segond P, et al: Role of blood pressure, uric acid, and hemorheological parameters on plasma homocyst(e)ine concentration. Atherosclerosis. 1995, 114: 175-183. 10.1016/0021-9150(94)05481-W.
Article
CAS
PubMed
Google Scholar
Kielstein JT, Salpeter SR, Buckley NS, Cooke JP, Fliser D: Two cardiovascular risk factors in one? Homocysteine and its relation to glomerular filtration rate. A meta-analysis of 41 studies with 27,000 participants. Kidney Blood Press Res. 2008, 31: 259-267. 10.1159/000142725.
Article
CAS
PubMed
Google Scholar
Firmann M, Mayor V, Vidal PM, Bochud M, Pecoud A, Hayoz D, et al: The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome. BMC Cardiovasc Disord. 2008, 8: 6-10.1186/1471-2261-8-6.
Article
PubMed
PubMed Central
Google Scholar
El Assaad MA, Topouchian JA, Darne BM, Asmar RG: Validation of the Omron HEM-907 device for blood pressure measurement. Blood Press Monit. 2002, 7: 237-241. 10.1097/00126097-200208000-00006.
Article
PubMed
Google Scholar
Brosius FC, Hostetter TH, Kelepouris E, Mitsnefes MM, Moe SM, Moore MA, et al: Detection of chronic kidney disease in patients with or at increased risk of cardiovascular disease: a science advisory from the American Heart Association Kidney And Cardiovascular Disease Council; the Councils on High Blood Pressure Research, Cardiovascular Disease in the Young, and Epidemiology and Prevention; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: developed in collaboration with the National Kidney Foundation. Circulation. 2006, 114: 1083-1087. 10.1161/CIRCULATIONAHA.106.177321.
PubMed
Google Scholar
Levey AS, Coresh J, Balk E, Kausz AT, Levin A, Steffes MW, et al: National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med. 2003, 139: 137-147.
Article
PubMed
Google Scholar
Cockcroft DW, Gault MH: Prediction of creatinine clearance from serum creatinine. Nephron. 1976, 16: 31-41. 10.1159/000180580.
Article
CAS
PubMed
Google Scholar
Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, et al: A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet. 1995, 10: 111-113. 10.1038/ng0595-111.
Article
CAS
PubMed
Google Scholar
Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, et al: Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet. 2008, 40: 768-775. 10.1038/ng.140.
Article
CAS
PubMed
PubMed Central
Google Scholar
Casas JP, Bautista LE, Smeeth L, Sharma P, Hingorani AD: Homocysteine and stroke: evidence on a causal link from mendelian randomisation. Lancet. 2005, 365: 224-232.
Article
CAS
PubMed
Google Scholar
Jamison RL, Shih MC, Humphries DE, Guarino PD, Kaufman JS, Goldfarb DS, et al: Effect of the MTHFR C677T and A1298C polymorphisms on survival in patients with advanced CKD and ESRD: a prospective study. Am J Kidney Dis. 2009, 53: 779-789. 10.1053/j.ajkd.2008.12.023.
Article
CAS
PubMed
Google Scholar
Wald DS, Law M, Morris JK: Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ. 2002, 325: 1202-10.1136/bmj.325.7374.1202.
Article
PubMed
PubMed Central
Google Scholar
Lauszus FF, Gron PL, Klebe JG: Association of polymorphism of methylene-tetrahydro-folate-reductase with urinary albumin excretion rate in type 1 diabetes mellitus but not with preeclampsia, retinopathy, and preterm delivery. Acta Obstet Gynecol Scand. 2001, 80: 803-806. 10.1034/j.1600-0412.2001.080009803.x.
Article
CAS
PubMed
Google Scholar
Mtiraoui N, Ezzidi I, Chaieb M, Marmouche H, Aouni Z, Chaieb A, et al: MTHFR C677T and A1298C gene polymorphisms and hyperhomocysteinemia as risk factors of diabetic nephropathy in type 2 diabetes patients. Diabetes Res Clin Pract. 2007, 75: 99-106. 10.1016/j.diabres.2006.05.018.
Article
CAS
PubMed
Google Scholar
Neugebauer S, Baba T, Watanabe T: Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in NIDDM patients. Lancet. 1998, 352: 454-
Article
CAS
PubMed
Google Scholar
Noiri E, Taguchi J, Nakao A, Fujita T: MTHFR gene polymorphism as an exacerbation factor of diabetic nephropathy in type 2 diabetes. Analysis in Japanese male hemodialysis patients. Diabetes Care. 2000, 23: 260-
Article
CAS
PubMed
Google Scholar
Sun J, Xu Y, Zhu Y, Lu H: Genetic polymorphism of methylenetetrahydrofolate reductase as a risk factor for diabetic nephropathy in Chinese type 2 diabetic patients. Diabetes Res Clin Pract. 2004, 64: 185-190. 10.1016/j.diabres.2003.10.022.
Article
CAS
PubMed
Google Scholar
Boger CA, Stubanus M, Haak T, Gotz AK, Christ J, Hoffmann U, et al: Effect of MTHFR C677T genotype on survival in type 2 diabetes patients with end-stage diabetic nephropathy. Nephrol Dial Transplant. 2007, 22: 154-162.
Article
PubMed
Google Scholar
Wiltshire EJ, Mohsin F, Chan A, Donaghue KC: Methylenetetrahydrofolate reductase and methionine synthase reductase gene polymorphisms and protection from microvascular complications in adolescents with type 1 diabetes. Pediatr Diabetes. 2008, 9: 348-353. 10.1111/j.1399-5448.2008.00374.x.
Article
CAS
PubMed
Google Scholar
Baud L, Ardaillou R: Involvement of reactive oxygen species in kidney damage. Br Med Bull. 1993, 49: 621-629.
CAS
PubMed
Google Scholar
Ninomiya T, Kiyohara Y, Kubo M, Tanizaki Y, Tanaka K, Okubo K, et al: Hyperhomocysteinemia and the development of chronic kidney disease in a general population: the Hisayama study. Am J Kidney Dis. 2004, 44: 437-445.
Article
PubMed
Google Scholar
Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY: Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004, 351: 1296-1305. 10.1056/NEJMoa041031.
Article
CAS
PubMed
Google Scholar
O'Callaghan P, Meleady R, Fitzgerald T, Graham I: Smoking and plasma homocysteine. Eur Heart J. 2002, 23: 1580-1586. 10.1053/euhj.2002.3172.
Article
PubMed
Google Scholar