Table 3 Meta-analytic methods used in the NICE public health intervention appraisals to synthesise the effectiveness evidence

NG105

Evidence review 1: Multi-agency partnerships

E,CE

\(\checkmark \)

\(\checkmark \)

Suicide rate

RR

MA

nr

\(\checkmark \)

Txt

nr

NG105

Evidence review 4: Information, advice, education and training

E,CE

\(\checkmark \)

\(\checkmark \)

Suicide attempts

RR / change in %

MA

nr

\(\checkmark \)

\(\checkmark \)

Components that provide information, advice, education for staff or public.

Txt

nr

NG105

Evidence review 6: Reducing access to means

E,CE

\(\checkmark \)

\(\checkmark \)

Suicide rate

IRR / difference in number

MA

nr

\(\checkmark \)

\(\checkmark \)

Physical barriers, surveillance, encouraging help-seeking.

T

nr

NG102

Evidence review 3: Offering behavioural support to promote health and wellbeing

E, CE, DM

\(\checkmark \)

\(\checkmark \)

Weight change

MD

MA

R

\(\checkmark \)

FP/Txt

RevMan

NG103

Evidence review 2: Increasing flu vaccination uptake in children

E,CE

\(\checkmark \)

Uptake of vaccinations

RR

MA

R

FP/Txt/T

RevMan

NG103

Evidence review 3: Increasing flu vaccination uptake in clinical risk groups

E,CE

\(\checkmark \)

Uptake of vaccinations

RR

MA

R

FP/Txt/T

RevMan

NG103

Evidence review 4: Increasing flu vaccination uptake in health and social care staff

E,CE

\(\checkmark \)

Uptake of vaccinations

RR

MA

R

FP/Txt/T

RevMan

NG92

Non NHS treatments for smoking cessation

E

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

Smoking cessation

OR

MA

R

FP/Txt

Revman

NG58

Evidence review 3 - The effectiveness and efficiency of service delivery models for health, social care and voluntary and community sector organisations at meeting the needs of people with a severe mental illness who also misuse substances

E

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

Mental and physical health outcomes (including mortality, recovery and relapse, physical morbidity)

RR

MA

R

FP/Txt

RevMan

NG55

Evidence review 2 - Assessment

E

\(\checkmark \)

\(\checkmark \)

Recidivism

Area under curve

MA

R

FP/Txt

R (meta-for)

NG48

Evidence review 1

E

\(\checkmark \)

\(\checkmark \)

Plaque index / gingival index

SMD

MA

R

\(\checkmark \)

\(\checkmark \)

Assessments of oral health, maintaining access to dental ser- vices, staff training, oral health education, providing oral health resources.

FP/Txt

Stata

NG44

Evidence review 2 - Community engagement 2015 - Brunton

E

\(\checkmark \)

\(\checkmark \)

Self-efficacy post test outcome

SMD

MA

R

\(\checkmark \)

Community engage- ment components: coalitions, collabo- rations, stakeholder involvement, advisory groups or partnerships.

FP/Txt

Stata (metareg)

NG44

Evidence review 3 - Community engagement 2015 - Stokes

E

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

Behavioural outcomes

SMD

MA

R

FP/Txt

\(\checkmark \)

Stata (metareg)

Reference number

articles

Evidence type

Quality grading of evidence

Includes RCTs only

Final outcome

Description of main outcome

Outcome measure statistic

Type of synthesis

M-A: Fixed or Random (F/R)

Lumping multiple interventions in comparison

Potential intervention components

Details of intervention components

Presentation of results

Assessed publication bias

Software

PH54

Evidence review 1 - A systematic review and economic evaluation - a short report

E, CE

\(\checkmark \)

\(\checkmark \)

Physical activity (self-report or objectively monitored), physical fitness (e.g. maximal oxygen uptake (VO2max), health outcomes (e.g. blood pressure), adverse events (e.g. musculoskeletal injury), and uptake and adherence to ERS.

MD

MA

R

\(\checkmark \)

Combination of coun- selling, written materi- als, supervised exercise training.

FP/Txt

RevMan

PH53

Evidence review 1a

E

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

BOCF weight change

MD

MA

F

\(\checkmark \)

\(\checkmark \)

Multi-component weight management programmes.

FP/Txt

RevMan

PH53

Evidence review 1b

E

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

BOCF weight change

MD

MA

R

\(\checkmark \)

\(\checkmark \)

Multi-component weight management programmes.

FP/Txt/T

nr

PH53

Evidence review 1c

E

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

BOCF weight change

MD

MA

R

\(\checkmark \)

\(\checkmark \)

Multi-component weight management programmes.

FP/Txt/T

nr

PH48

Review 2 – Effectiveness of smoking cessation interventions in acute and maternity services

E

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

Abstinence from smoking at least six months after the start of the intervention

OR

MA

F

FP/Txt

RevMan

PH48

Review 3 – Barriers & facilitators for smoking cessation interventions in acute and maternity services

E

\(\checkmark \)

\(\checkmark \)

Impact of stopping smoking shortly before surgery on surgery outcomes / complications

RR

MA

R

FP/Txt

RevMan

PH48

Review 4 – Effectiveness of smoking cessation interventions in mental health services

E

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

Participants who made successful quit attempts

OR

MA

R

\(\checkmark \)

\(\checkmark \)

Pharmacological, psychological, be- havioural, or self-help intervention components

FP/Txt

\(\checkmark \)

RevMan

PH47

Review of effectiveness and cost effectiveness

E, CE

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

BMI, Zbmi

SMD

MA

R

\(\checkmark \)

\(\checkmark \)

Diet, physical activity, behaviour change inter- vention components.

FP/Txt

\(\checkmark \)

Stata

PH44

Review of effectiveness and barriers and facilitators

E

\(\checkmark \)

\(\checkmark \)

Self-reported physical activity

Mean, RR

MA

R

FP/Txt

RevMan

PH38

Evidence reviews

E, CE, DM

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

Progression to T2 Diabetes

Other

MA

R

\(\checkmark \)

FP

RevMan

PH38

R2 systematic review and meta-analysis of lifestyle, pharmacological and surgical interventions

E

\(\checkmark \)

\(\checkmark \)

\(\checkmark \)

Progression to T2 Diabetes

HR

MA and NMA

R

\(\checkmark \)

\(\checkmark \)

Lifestyle, drug, and sur- gical intervention com- ponents.

FP/Txt

RevMan