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Table 3 Stratified analysis for the association of smoking habit change on cardiovascular disease according to subgroups of aspirin or warfarin use

From: Association of smoking cessation after atrial fibrillation diagnosis on the risk of cardiovascular disease: a cohort study of South Korean men

  Adjusted hazard ratio (95% confidence interval)a 
  Continual smokersQuittersSustained ex-smokersNever smokersp for trend
Cardiovascular diseaseAspirin use
 No1.00 (reference)0.59 (0.31–1.13)0.55 (0.34–0.90)0.55 (0.35–0.86)0.013
 Yes1.00 (reference)0.70 (0.42–1.16)0.94 (0.65–1.35)0.80 (0.56–1.14)0.361
Warfarin use
 No1.00 (reference)0.66 (0.43–1.03)0.71 (0.51–0.98)0.73 (0.54–0.99)0.073
 Yes1.00 (reference)0.45 (0.18–1.13)0.85 (0.45–1.61)0.52 (0.28–0.97)0.088
Total strokeAspirin use
 No1.00 (reference)0.63 (0.26–1.54)0.44 (0.21–0.91)0.71 (0.38–1.31)0.269
 Yes1.00 (reference)0.83 (0.40–1.69)1.04 (0.61–1.77)0.79 (0.47–1.33)0.423
Warfarin use
 No1.00 (reference)0.70 (0.38–1.29)0.74 (0.46–1.16)0.78 (0.51–1.20)0.343
 Yes1.00 (reference)0.64 (0.17–2.46)0.85 (0.31–2.35)0.54 (0.20–1.49)0.255
Coronary heart diseaseAspirin use
 No1.00 (reference)0.53 (0.22–1.29)0.60 (0.31–1.14)0.46 (0.25–0.84)0.018
 Yes1.00 (reference)0.62 (0.32–1.19)0.87 (0.55–1.38)0.83 (0.54–1.29)0.661
Warfarin use
 No1.00 (reference)0.64 (0.36–1.15)0.68 (0.44–1.04)0.74 (0.50–1.10)0.197
 Yes1.00 (reference)0.32 (0.10–1.03)0.67 (0.32–1.42)0.41 (0.20–0.86)0.053
  1. aHazard ratios calculated by Cox proportional hazards regression analysis after adjustments for age, household income, alcohol consumption, physical exercise, body mass index, systolic blood pressure, fasting serum glucose, total cholesterol, Charlson comorbidity index, aspirin use, warfarin use, and index year
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