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Table 2 Likelihood of treatment discontinuation <25 weeks after treatment initiation: logistic regression results

From: Tuberculosis treatment discontinuation and symptom persistence: an observational study of Bihar, India’s public care system covering >100,000,000 inhabitants

  Univariate regression Multivariate regressions
  All patients All patients Patients with prior TB Patients with no prior TB
  OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
Prior TB status         
Prior TB treatment episode 6.15* (2.60 - 14.53) 4.77* (1.98 - 11.53)     
Prior TB & completed prior treatment 0.23* (0.09 - 0.60) 0.22* (0.08 - 0.59) 0.15* (0.03 - 0.73)   
Current illness treatment and illness characteristics         
Total weeks from symptom onset to treatment initiation 1.00 (0.95 - 1.05) 1.02 (0.97 - 1.07) 1.04 (0.90 - 1.20) 1.02 (0.97 - 1.08)
Number of Providers visited 4.68* (2.64 - 8.27) 3.67* (1.94 - 6.95) 3.08 (0.46 - 20.45) 5.62* (2.32 - 13.66)
Treatment or medication fees 6.83* (2.18 - 21.41) 4.60* (1.38 - 15.40) 1.13 (0.08 - 16.48) 6.32* (1.43 - 28.00)
Travel costs 2.70* (1.07 - 6.82) 2.55* (1.03 - 6.33) 1.43 (0.13 - 16.08) 4.39* (1.36 - 14.13)
Treatment, medication and travel costs 0.21* (0.06 - 0.69) 0.34 (0.10 - 1.18) 1.04 (0.05 - 21.04) 0.19 (0.03 - 1.06)
2 or fewer symptoms at treatment initiation** 1.18 (0.75 - 1.85) 1.62 (0.96 - 2.73) 4.20* (1.26 - 13.92) 1.29 (0.76 - 2.21)
3-4 symptoms at treatment initiation** 1.38 (0.74 - 2.56) 1.54 (0.83 - 2.86) 2.55 (0.66 - 9.95) 1.16 (0.65 - 2.09)
Patient and household characteristics         
Male 1.29 (0.85 - 1.95) 1.32 (0.82 - 2.14) 1.02 (0.39 - 2.69) 1.34 (0.81 - 2.22)
Age 0.96 (0.91 - 1.00) 0.96 (0.91 - 1.01) 0.84 (0.70 - 1.01) 0.98 (0.93 - 1.03)
Age squared 1.00 (1.00 - 1.00) 1.00 (1.00 - 1.00) 1.00* (1.00 - 1.00) 1.00 (1.00 - 1.00)
Education 1.01 (0.96 - 1.06) 0.99 (0.93 - 1.06) 0.75* (0.58 - 0.98) 1.01 (0.95 - 1.07)
Hindu 0.83 (0.51 - 1.35) 0.81 (0.47 - 1.40) 0.25* (0.08 - 0.78) 0.97 (0.51 - 1.84)
Scheduled Caste, Tribe, other backwards class 0.87 (0.53 - 1.44) 0.84 (0.47 - 1.50) 0.36 (0.08 - 1.71) 1.02 (0.51 - 2.02)
Number of Kids 0.95 (0.82 - 1.09) 1.02 (0.86 - 1.21) 0.80 (0.53 - 1.20) 1.08 (0.89 - 1.31)
Household size 0.97 (0.88 - 1.06) 0.96 (0.86 - 1.07) 1.35 (0.97 - 1.88) 0.92 (0.81 - 1.04)
Poor 1.09 (0.68 - 1.74) 0.97 (0.56 - 1.66) 0.76 (0.14 - 4.11) 1.27 (0.73 - 2.19)
Middle income 0.70 (0.36 - 1.36) 0.86 (0.48 - 1.54) 0.99 (0.30 - 3.20) 0.95 (0.56 - 1.61)
Observations 1007 1007 196 811
  1. *p < 0.05.
  2. **Comparator group is ≥5 Symptoms at Treatment Initiation.