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Table 2 Likelihood of treatment discontinuation <25 weeks after treatment initiation: logistic regression results

From: Tuberculosis treatment discontinuation and symptom persistence: an observational study of Bihar, India’s public care system covering >100,000,000 inhabitants

 

Univariate regression

Multivariate regressions

 

All patients

All patients

Patients with prior TB

Patients with no prior TB

 

OR

(95% CI)

OR

(95% CI)

OR

(95% CI)

OR

(95% CI)

Prior TB status

        

Prior TB treatment episode

6.15*

(2.60 - 14.53)

4.77*

(1.98 - 11.53)

    

Prior TB & completed prior treatment

0.23*

(0.09 - 0.60)

0.22*

(0.08 - 0.59)

0.15*

(0.03 - 0.73)

  

Current illness treatment and illness characteristics

        

Total weeks from symptom onset to treatment initiation

1.00

(0.95 - 1.05)

1.02

(0.97 - 1.07)

1.04

(0.90 - 1.20)

1.02

(0.97 - 1.08)

Number of Providers visited

4.68*

(2.64 - 8.27)

3.67*

(1.94 - 6.95)

3.08

(0.46 - 20.45)

5.62*

(2.32 - 13.66)

Treatment or medication fees

6.83*

(2.18 - 21.41)

4.60*

(1.38 - 15.40)

1.13

(0.08 - 16.48)

6.32*

(1.43 - 28.00)

Travel costs

2.70*

(1.07 - 6.82)

2.55*

(1.03 - 6.33)

1.43

(0.13 - 16.08)

4.39*

(1.36 - 14.13)

Treatment, medication and travel costs

0.21*

(0.06 - 0.69)

0.34

(0.10 - 1.18)

1.04

(0.05 - 21.04)

0.19

(0.03 - 1.06)

2 or fewer symptoms at treatment initiation**

1.18

(0.75 - 1.85)

1.62

(0.96 - 2.73)

4.20*

(1.26 - 13.92)

1.29

(0.76 - 2.21)

3-4 symptoms at treatment initiation**

1.38

(0.74 - 2.56)

1.54

(0.83 - 2.86)

2.55

(0.66 - 9.95)

1.16

(0.65 - 2.09)

Patient and household characteristics

        

Male

1.29

(0.85 - 1.95)

1.32

(0.82 - 2.14)

1.02

(0.39 - 2.69)

1.34

(0.81 - 2.22)

Age

0.96

(0.91 - 1.00)

0.96

(0.91 - 1.01)

0.84

(0.70 - 1.01)

0.98

(0.93 - 1.03)

Age squared

1.00

(1.00 - 1.00)

1.00

(1.00 - 1.00)

1.00*

(1.00 - 1.00)

1.00

(1.00 - 1.00)

Education

1.01

(0.96 - 1.06)

0.99

(0.93 - 1.06)

0.75*

(0.58 - 0.98)

1.01

(0.95 - 1.07)

Hindu

0.83

(0.51 - 1.35)

0.81

(0.47 - 1.40)

0.25*

(0.08 - 0.78)

0.97

(0.51 - 1.84)

Scheduled Caste, Tribe, other backwards class

0.87

(0.53 - 1.44)

0.84

(0.47 - 1.50)

0.36

(0.08 - 1.71)

1.02

(0.51 - 2.02)

Number of Kids

0.95

(0.82 - 1.09)

1.02

(0.86 - 1.21)

0.80

(0.53 - 1.20)

1.08

(0.89 - 1.31)

Household size

0.97

(0.88 - 1.06)

0.96

(0.86 - 1.07)

1.35

(0.97 - 1.88)

0.92

(0.81 - 1.04)

Poor

1.09

(0.68 - 1.74)

0.97

(0.56 - 1.66)

0.76

(0.14 - 4.11)

1.27

(0.73 - 2.19)

Middle income

0.70

(0.36 - 1.36)

0.86

(0.48 - 1.54)

0.99

(0.30 - 3.20)

0.95

(0.56 - 1.61)

Observations

1007

1007

196

811

  1. *p < 0.05.
  2. **Comparator group is ≥5 Symptoms at Treatment Initiation.