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A cross sectional assessment of knowledge, attitude and practice towards Hepatitis B among healthy population of Quetta, Pakistan



Hepatitis B (HB) is a serious global public health problem. This study aims to evaluate Knowledge, Attitude and Practice (KAP) towards Hepatitis B (HB) among healthy population of Quetta city, Pakistan.


A cross sectional, descriptive study was undertaken. One thousand healthy individuals (aged 18 years and above) were approached for the study. KAP towards HB was assessed by using a pre validated questionnaire. Descriptive statistics were used for elaborating patients’ demographic characteristics. Inferential statistics (Mann–Whitney U test and Kruskal Wallis test) were used for comparison while Spearman’s rho correlation was used to identify association between the study variables. All analyses were performed using SPSS 16.0.


Out of 1000 distributed questionnaires, 780 were returned with a response rate of 78.0%. Four hundred and twenty (53.8%) respondents were male with mean age of 32.76 ± 9.40 year. Two hundred and eight (26.7%) had intermediate level of education and 354 (45.4%) were unemployed. Mean scores for knowledge, attitude and practice were 8.74 ± 2.7, 3.72 ± 1.2 and 2.76 ± 1.1 respectively. Significant and positive linear correlations between knowledge-attitude (r = 0.296, p < 0.01) knowledge-practice (r = 0.324, p < 0.01) and attitude-practice (r = 0.331, p < 0.01) were observed. Area of residence (locality) was the only variables significantly associated with mean KAP of the study respondents.


Results from the current study heighted poor KAP of healthy population towards HB. The positive linear correlations reaffirms that better knowledge can lead to positive attitude and subsequently in good practices. This will further help in prevention and management of HB. Therefore, extensive health educational campaign should be provided to general population and especially to the residents of rural areas.

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Hepatitis B (HB) is a serious and common infectious disease of the liver. The World Health Organization (WHO) in 2009 reported HB to infect nearly 2 billion people around the globe. Furthermore, out of those 2 billion, 350 million suffered from chronic, lifelong infection [1]. Moreover, an estimated 15–40% of chronic HB carriers were susceptible to develop liver cirrhosis and hepatocellular carcinoma [2, 3]. HB is a confronting ailment and results in 0.6 million deaths annually [4, 5]. Although HB is classified as ‘disease of priority,’ there is an incessant increase in detection of new cases worldwide [6]. Furthermore, HB is widespread in the Asia Pacific region and 10 to 15 million of the population suffer from this disease [79]. Similar to what is reported worldwide, the incidence of HB infection is on continuous rise in Pakistan [10]. The pervasiveness of HB ranges between 7 to 20% in Pakistani population and varies from region to region [9, 1115]. In metropolitan cities like Karachi, the prevalence of HB is reported lower (2-5%) as compared with the rural areas which can range from where 30-35% [11, 13, 15]. Based on these statistics, Pakistan is classified as a region of ‘intermediate risk’ towards HB by WHO [1].

The health system of Pakistan consists of both private and public sectors. The private health sector serves nearly 70% of the population, whereas the public sector comprises more than 10,000 health facilities, ranging from basic health units (BHUs) to tertiary referral centers [16]. Within this context, Quetta is the largest city and the provincial capital of the Balochistan Province of Pakistan. The city is located near the Durand Line border with Afghanistan and is the only city in with adequate health institutes and facilities. The area holds the attraction for treatment of acute and chronic diseases both for the local population as well as immigrants from Afghanistan and Iran.

Knowledge, attitude, and practice (KAP) surveys are representative of a specific population to collect information on what is known, believed and done in relation to a particular topic, and are the most frequently used study tool in health-seeking behavior research [17]. Knowledge is usually assessed in order to see how far community knowledge corresponds to biomedical concepts [18]. Typical questions include knowledge about causes and symptoms of the illness under investigation. People reported knowledge which deviates from biomedical concepts is usually termed as ‘beliefs’ [19]. Attitude has been defined as “a learned predisposition to think, feel and act in a particular way towards a given object or class of objects” [20]. As such, attitude is a product of a complex interaction of beliefs, feelings, and values. Practices in KAP surveys usually enquire about the use of preventive measures or different health care options. Normally, hypothetical questions are asked, therefore it hardly permits statements about actual practices, rather, it yields information on people’s behaviors or on what they know should be done [21].

As discussed earlier, the frequency of HB is increasing progressively worldwide, prevention is considered as one best way to safeguard populations’ health. Deterrence can also lead to decreased spread of HB virus thus reducing the chances of disease conduction. Prevention against any disease is proportional to KAP of the population and is reflective of the importance that is paid to health related issues by the society. Therefore, KAP studies play an imperative role in determining the ambiguities of a society and are widely used in population reported assessment research worldwide. To the contrary, there is paucity of data from Pakistan and KAP towards HB among healthy population is never explored. In spite of the efforts made by authorities to raise knowledge and awareness about HB, no progress is reported. In the present scenario, there is a need to assess the KAP status of healthy individuals towards HB so that the information can be used to develop a better and need based program for the society. The current study aimed to assess knowledge, attitudes and practices (KAP) of healthy population towards HB from Quetta city, Pakistan.


Study design and settings

This descriptive study was designed as questionnaire based, cross sectional analysis. Healthy population from Quetta city, Pakistan was targeted for the study. The study questionnaire was distributed at places of common interest (shopping malls, educational institutes, households etc.). Participants were requested to answer the questionnaire on spot and were subsequently collected after completion.

Study sample

By employing convenience sampling method, 1000 respondents were targeted for the study. The study was conducted from April 2011 to July 2011. Healthy individuals aging 18 years and above, with no physical and mental mutilation, not using any type of medication, and familiarity with Urdu (National language of Pakistan) were included in the study. Patients having reported illness and immigrants from other countries were excluded from data collection.

Ethical approval

This study was performed according to the ethical standards for human experimentation [22]. The Joint Clinical Research Committee approved the study protocol (No: EA/NUH/1205-2009). Written consent was also taken from the respondents before initiation of the research.

Study instrument

A self administered, 35 itemed questionnaire comprising of four sections was used for data collection. In addition to the demographic data, 20 questions explored knowledge towards HB, 7 questions focused on attitude and 8 questions addressed practices towards HB. Respondents were asked to answer in limited as well as multiple choice formats. The primary version of the questionnaire was developed through extensive literature review in English language [17, 23]. It was later translated into Urdu language by using standard translating procedures [24, 25]. The Urdu version of the questionnaire was tested for its reliability and validity. Internal consistency was assessed by using Cronbach’s alpha (α = 0.7) and was found to be in acceptable ranges [26]. Face, content and convergent validity of the questionnaire was performed by experts at Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia. The questionnaire was than piloted with 30 respondents for its acceptability and consistency. Little modification was needed after the pilot testing. Data from the pilot study was not included in the final analysis. As the consistency and validity of the study questionnaire was stabilized, the instrument was made available for data collection.

Statistical analysis

Descriptive statistics were used to illustrate respondents’ demographic characteristics. Categorical variables were measured as percentages while continuous variables were expressed as mean ± standard deviation. The Kolmogrov-Smirnov test was applied to declare the nature of data distribution. Inferential statistics (Mann–Whitney U test and Kruskal Wallis tests) were used to assess the difference while Spearman's rank correlation coefficient was used to evaluate the relationship between the study variables. A p value of <0.05 was taken as significant for Mann–Whitney U test and Kruskal Wallis test. In addition, p < 0.01 was taken as significant for correlation analysis. Statistical Package for Social Sciences (SPSS) v. 16.0 was sued for data analysis.


Demographic characteristics

A total of 1000 questionnaires were distributed and 780 were received with a response rate of 78.0% as shown in Table 1. The Kolmogrov-Smirnov test revealed non normal distribution of the data. The gender distribution was almost equal with 417 (53.5%) of males. Mean age of the study participants was 32.7 ± 9.40 years with 428 (54.9%) having urban residency. One hundred and ninety eight (25.4%) had intermediate level of education and 364 (46.7%) were unemployed (including house wives and students). One hundred and twenty two (15.6%) had monthly income of Pakistan Rupees (Pk. Rs) of in between 5001-10,000. The major source of information regarding HB was from family/friend/neighbors 284 (36.4%), followed by 138 (17.7%) by HB information leaflets/brochures and posters.

Table 1 Characteristics of the study respondents (N = 780)

Assessment of knowledge towards Hepatitis B

Table 2 describes the responses of the participants towards HB knowledge. Knowledge was assessed by questions focusing on HB etiology, sign and symptoms, transmission, treatment and management. Each response was scored as ‘yes’ or ‘no’. The scoring range of the questionnaire was 20 (maximum) to 0 (minimum). A cut off level of ≤ 11 was considered as poor whereas > 11 was considered as adequate knowledge about HB. Knowledge scores for individuals were calculated and summed up to give the total knowledge score.

Table 2 Responses to Hepatitis B knowledge items

Out of the 780 participants, 588 (75.4%) were within the poor knowledge range whereas 192 (24.6%) showed adequate knowledge about HB. Poor knowledge was apparent in responses to questions relating to symptoms (question 7-10) and transmission of HB (question 11-16). Correct answers to these questions were 17.7, 32.3, 20.9 and 18.6% for symptoms while 34.0, 37.9, 33.3, 10.1, 24.0, and 31.0% for transmission of HB respectively. Correct answers, 97.8, 84.0, 76.7 and 83.2% were highest in response to questions 1,2,19 and 20 respectively. The mean knowledge score for the entire study cohort was 8.74 ± 2.7.

Assessment of attitude towards Hepatitis B

Attitude towards HB was assessed by asking seven questions as shown in Table 3. Each question was labeled with positive or negative attitude. A score of 1 was given to positive while 0 was given to negative attitudes with a score range of maximum of 7 to a minimum of 0. The scale classified attitude as positive with score > 4 and negative ≤ 4. Majority of the respondent 622 (79.7%) believed that they can never get infected with HB. Three hundred and eight (39.5%) respondents stated that they will be ashamed to get infected with HB. Five hundred and forty nine (70.4%) of the study respondents were of opinion to use complementary and alternative system in case of HB infection. In addition, 203 (26.0%) agreed to consult a physician as their first choice of treatment. However, respondents were ready to disclose their disease to their spouse (n = 367, 47.1%) and parents (n = 207, 26.5%). Over all the respondents had a negative attitude towards Hepatitis B with mean score of 3.72 ± 1.2.

Table 3 Attitude toward Hepatitis B

Assessment of practices towards Hepatitis B

Practices towards HB were assessed by asking eight questions as shown in Table 4. Each question was labeled with good or poor practice. A score of 1 was given to good while 0 was given to bad practice with a score range of maximum of 8 to a minimum of 0. The scale classified practice as good with score > 5 and poor ≤ 5. Majority of the respondents, 756 (96.9%) never went for HB screening and 674 (86.8%) stated a negative immunized status against HB. It was interesting to know that 634 (81.8%) never asked for a new syringe when required, while only 344 (44.1%) agreed with the statement that they ask for screening of blood and blood products before transfusion. Six hundred and thirty one (80.9%) respondents either never asked the barber to use new blade, or for safe and clean equipment for nose and ear piercing. However, on the contrary majority of the study participants (n = 635, 81.4%) revealed that they avoid meeting a person infected with HB. Majority 731 (93.7%) agreed that they will go for further investigation and treatment if they are infected with HB. In addition, a small number of respondents (n = 14, 1.8) have ever attended any educational program on HB. The mean score for HB related practices was 2.76 ± 1.1 revealing poor practices among the study participants.

Table 4 Practice related to Hepatitis B

Association of demographic characteristics and mean KAP Scores

The association of demographic characteristics and mean KAP scores is presented in Table 5. Among the demographic variables, only area of residence (locality) was significantly associated with mean KAP scores (p < 0.01).

Table 5 Comparison of Demographic Characteristics and Mean KAP Scores

Correlation between knowledge, attitude and practice

Correlations were interpreted using the following criteria: 0–0.25 = weak correlation, 0.25–0.5 = fair correlation, 0.5–0.75 = good correlation and greater than 0.75 = excellent correlation [27]. The correlation revealed significant positive linear correlations between knowledge-attitude (r = 0.296, p < 0.01) knowledge-practice (r = 0.324, p < 0.01) and attitude-practice (r = 0.331, p < 0.01). The result reaffirms the relationship between knowledge attitude and practice with infection control measures as shown in Table 6.

Table 6 Correlation between knowledge, attitude, and practice scores


The current study sought to evaluate KAP towards HB among healthy individuals. Results of the study revealed poor KAP towards HB. The mean knowledge score was 8.74 ± 2.7 indicating low level of knowledge towards HB among the study cohort. A small percentage of respondents actually knew about transmission of HB. Lack of knowledge about HB transmission can be attributed to rise in the frequency of HB. Only 28.2% of the participant believed that HB can cause liver cancer, which is again a major sign of concern. The primary source of information was through family, friends and neighbors. These results are in line with the findings from studies reported from other parts of Pakistan where the overall knowledge of the general population regarding HB was reported low [28, 29]. Similar to what is reported from Pakistan, poor knowledge regarding HB also is also reported around the globe [3037]. On the contrary Shalaby et al. (2007) in Egypt reported that participants had adequate knowledge towards transmission, vaccination and treatment of HB [38]. Possible reasons that can be attributed to this difference of response are demographic variation of the study population, study location and as well as the study tool used for data collection.

In addition, mean attitude score was also found lower in the study participants. Majority of the participants reported to use complementary and alternative medicines if infected with HB. Home remedies, herbal and traditional therapies were the treatment of choice until there is no improvement in the sign and symptoms of HB. Consulting the physicians was sought as the last resort, when all other healing system fails to provide cure. This is similar to what is reported by a study of same nature in Pakistan [28]. It is imperative to account that delay in seeking medical treatment for the infection results in further deterioration of the condition and can cause spread of infections.

An important feature of patient care revolves around the Health Belief Model which highlights individuals’ attitudes and beliefs responsible for particular health behaviour [39]. In addition, perceived benefits and barriers in the health care regimen play a vital role in achieving therapeutic success. Results from the current study revealed that general population is in habit of making independent assessments of their current health status and were favoring different health systems (spiritual healers, yunani, ayurvedic and homeopathic healing systems) resulting in medical pluralism. Multiple opinions from such entities can complicate and disseminate irrational information and practices towards HB in the population. Although some of the systems are not approved by the official authorities in Pakistan, their influence is pronounced in the population. The results notwithstanding, it is important that the general population should be educated on all aspects of HB rather than on a single or a few issues. It should also be addressed by social and medical researchers foregoing achieve a fuller understanding of the underlying issues while the outcome of such studies should be utilized in policy and decision-making by government officials and members of the health care team.

Within this context, poverty, cultural beliefs and perceived severity of illness can be the reasons of seeking alternative methods of treatment. Though not infected yet, majority of the participants perceived HB treatment as costly. This could be due to their experiences with friends and family members having difficulties in bearing the cost of HB treatment. Cost of treatment is another factor which forces the patients to seek help from traditional healers. In developing countries like Pakistan, access to the traditional healers is economical than seeking treatment at medical health care facilities.

Participants of the current study showed poor practice towards HB. Majority of the participants were not concerned about the safety measures which defiantly expose them to the danger of acquiring HB infection. Despite having awareness regarding the availability of HB vaccines, majority of the participants were not immunized against HB. Similar results were reported by Razi and colleagues in 2010 from Pakistan [40] and Kabir et al. in 2010 from Iran [41] where the participants reported to have poor practices which were directly related to the knowledge and awareness regarding HB infection. On the contrary, Shalaby et al. (2007) in Egypt reported the that the participants have good practice regarding hepatitis B hence have lower prevalence of infection [38]. Furthermore, the knowledge among participants was reported adequate by Shalaby et al., which is proportionately related to the attitude and practices of the participants.

Area of residence (locality) was the only significant factor associated the mean KAP scores. However, through extensive literature review, no studies were found to report the relation of locality and mean KAP scores. Cheung et al. in 2005 and Wu et al. in 2007 however reported education level as the significant factor associated with KAP scores of their study participants [32, 42].

The positive correlations between knowledge-attitude, knowledge-practice and attitude-practice in this study reaffirm the relationship between knowledge attitude and practice with infection control measures. It is concluded that adequate knowledge can lead to positive attitude resulting in good practices. The findings are in line with the results presented by Singh et al. in 2010 [43].


Summarizing the results of this study, these findings indicate a lack of understanding of the basics of infection control and the prevention of transmission of HB. Extensive health education campaign should be provided to general population and especially to the residents of rural areas. We recommend the adaptation of collaborative care where physicians, pharmacists and nurses should play their role in providing HB education to the society. Empowering the people by providing them ample education and targeting at least one member of each family to have adequate information about HB can help in managing and controlling the infection.


The study was conducted in one city and therefore results of the research are not representative of the entire population of Pakistan.


  1. World Health Organization: Hepatitis B. Fact sheet no: 204.,

  2. Lok ASF, McMahon BJ: Chronic hepatitis B. Hepatology. 2007, 45: 507-539. 10.1002/hep.21513.

    Article  CAS  PubMed  Google Scholar 

  3. Lee WM: Hepatitis B virus infection. N Engl J Med. 1997, 337: 1733-1745. 10.1056/NEJM199712113372406.

    Article  CAS  PubMed  Google Scholar 

  4. Mahoney FJ: Update on diagnosis, management, and prevention of hepatitis B virus infection. Clin Microbiol Rev. 1999, 12: 351-366.

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Keeffe EB, Dieterich DT, Han SHB, Jacobson IM, Martin P, Schiff ER, Tobias H: A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: 2008 update. Clin Gastroenterol Hepatol. 2008, 6: 1315-1341. 10.1016/j.cgh.2008.08.021.

    Article  CAS  PubMed  Google Scholar 

  6. Lok ASF, McMahon BJ: Chronic hepatitis B: update 2009. Hepatology. 2009, 50: 661-662. 10.1002/hep.23190.

    Article  PubMed  Google Scholar 

  7. Lesmana LA, Leung NWY, Mahachai V, Phiet PH, Suh DJ, Yao G, Zhuang H: Hepatitis B: overview of the burden of disease in the Asia Pacific region. Liver Int. 2006, 26: 3-10. 10.1111/j.1478-3231.2006.01370.x.

    Article  Google Scholar 

  8. Mohamed R, Desmond P, Suh DJ, Amarapurkar D, Gane E, Guangbi Y, Hou JL, Jafri W, Lai CL, Lee CH, Lee SD, Lim SG, Guan R, Phiet PH, Piratvisuth T, Sollano J, Wu JC: Practical difficulties in the management of hepatitis B in the Asia–Pacific region. J Gastroenterol Hepatol. 2004, 19: 958-969. 10.1111/j.1440-1746.2004.03420.x.

    Article  PubMed  Google Scholar 

  9. André F: Hepatitis B epidemiology in Asia, the middle East and Africa. Vaccine. 2000, 18: S20-S22.

    Article  PubMed  Google Scholar 

  10. Kumar A, Lalani S, Afridi KAA, Khuwaja KA: Screening of Hepatitis B and C among people visiting general practice clinics in a rural district of Sindh, Pakistan. J Ayub Med Coll. 2010, 22: 143-145.

    Google Scholar 

  11. Abdul MS, Jamal Q, Khanani R, Iqbal N, Kaher S: Prevalence of hepatitis B surface antigen and HCV antibodies in hepatocellular carcinoma cases in Karachi Pakistan. Trop Doct. 1997, 27: 45-

    Google Scholar 

  12. Agboatwalla M, Isomura S, Miyake K, Yamashita T, Morishita T, Akram DS: Hepatitis A, B and C seroprevalence in Pakistan. Indian J Pediatr. 1994, 61: 545-549. 10.1007/BF02751716.

    Article  CAS  PubMed  Google Scholar 

  13. Jafri W, Jafri N, Yakoob J, Islam M, Tirmizi SFA, Jafar T, Akhtar S, Hamid S, Shah H, Nizami S: Hepatitis B and C: prevalence and risk factors associated with seropositivity among children in Karachi Pakistan. BMC Infect Dis. 2006, 6: 101-10.1186/1471-2334-6-101.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Khattak M, Salamat N, Bhatti F, Qureshi T: Seroprevalence of hepatitis B, C and HIV in blood donors in northern Pakistan. J Pak Med Assoc. 2002, 52: 398-402.

    CAS  PubMed  Google Scholar 

  15. Khokhar N, Gill ML, Malik GJ: General seroprevalence of hepatitis C and hepatitis B virus infections in population. J Coll Physicians Surg Pak. 2004, 14: 534-

    PubMed  Google Scholar 

  16. Azhar S, Hassali MA, Ibrahim M, Ahmad M, Masood I, Shafie AA: The role of pharmacists in developing countries: the current scenario in Pakistan. Hum Resour Health. 2009, 7 (1): 54-10.1186/1478-4491-7-54.

    Article  PubMed  PubMed Central  Google Scholar 

  17. World Health Organization: Advocacy, communication and social mobilization for TB control: a guide to developing knowledge, attitude and practice surveys.,

  18. Good B: Medicine, rationality, and experience: an anthropological perspective. 1994, Cambridge Univ Pr, Cambridge

    Google Scholar 

  19. Tannahill A: Beyond evidence-to ethics: a decision-making framework for health promotion, public health and health improvement. Health Promot Int. 2008, 23: 380-390. 10.1093/heapro/dan032.

    Article  PubMed  Google Scholar 

  20. Ribeaux P, Poppleton SE: Psychology and Work: an introduction. 1978, Macmillan, London

    Book  Google Scholar 

  21. Yoder PS: Negotiating relevance: belief, knowledge, and practice in international health projects. Med Anthropol Q. 1997, 11: 131-146. 10.1525/maq.1997.11.2.131.

    Article  CAS  PubMed  Google Scholar 

  22. National Bioethics Committee Pakistan: Ethical Research Committee-Guidelines.,

  23. Alam M, Tariq WUZ: Knowledge, Attitudes and Practices about Hepatitis B and C among young healthy males. Pak J Pathol. 2006, 17: 147-150.

    Google Scholar 

  24. Behling O, Law KS: Translating questionnaires and other research instruments: Problems and solutions. 2000, Sage Publications, Inc, California

    Book  Google Scholar 

  25. Harkness JA, Schoua-Glusberg A: Questionnaires in translation. ZUMA-Nachrichten Spezial. 1998, 3: 87-127.

    Google Scholar 

  26. Santos JRA: Cronbach’s alpha: A tool for assessing the reliability of scales. J Extension. 1999, 37: 1-5.

    Google Scholar 

  27. Cohen J: Statistical power analysis for the behavioral sciences. Edited by: Hillsdale NJ. 1988, Lawrence Erlbaum, New Jersey, 2

    Google Scholar 

  28. Talpur AA, Memon N, Solangi R, Ghumro A: Knowledge and attitude of patients towards hepatitis B and C. Pak J Surg. 2007, 23: 162-165.

    Google Scholar 

  29. Haider G, Haider A: Awareness of women regarding hepatitis B. J Ayub Med Coll. 2008, 20: 141-144.

    Google Scholar 

  30. Taylor VM, Choe JH, Yasui Y, Li L, Burke N, Jackson JC: Hepatitis B awareness, testing, and knowledge among Vietnamese American men and women. J Community Health. 2005, 30: 477-490. 10.1007/s10900-005-7282-3.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Taylor VM, Tu SP, Woodall E, Acorda E, Chen H, Choe J, Li L, Yasui Y, Hislop TG: Hepatitis B knowledge and practices among Chinese immigrants to the United States. Asian Pac J Cancer Prev. 2006, 7: 313-

    PubMed  Google Scholar 

  32. Wu CA, Lin SY, So SK, Chang ET: Hepatitis B and liver cancer knowledge and preventive practices among Asian Americans in the San Francisco Bay Area California. Asian Pac J Cancer Prev. 2007, 8: 127-

    PubMed  Google Scholar 

  33. Thompson MJ, Taylor VM, Jackson JC, Yasui Y, Kuniyuki A, Tu SP, Hislop TG: Hepatitis B knowledge and practices among Chinese American women in Seattle, Washington. J Cancer Educ. 2002, 17: 222-226.

    PubMed  Google Scholar 

  34. Nguyen TT, Taylor V, Chen MS: Bastani R, Maxwell AE, McPhee SJ: Hepatitis B awareness, knowledge, and screening among Asian Americans. J Cancer Educ. 2007, 22: 266-272. 10.1007/BF03174128.

    Article  PubMed  Google Scholar 

  35. Lim HC, Rashwan H: Awareness of Hepatitis A and Hepatitis B among Residents in Kuala Lumpur and Selangor. Malaysian Journal of Pharmacy. 2003, 1: 76-85.

    Google Scholar 

  36. van der Veen YJJ, Voeten HACM, de Zwart O, Richardus JH: Awareness, knowledge and self-reported test rates regarding Hepatitis B in Turkish-Dutch: a survey. BMC Publ Health. 2010, 10: 512-10.1186/1471-2458-10-512.

    Article  Google Scholar 

  37. Leung C, Wong W, Chan K, Lai L, Luk Y, Lai J, Yeung Y, Hui W: Public awareness of hepatitis B infection: a population-based telephone survey in Hong Kong. Hong Kong Med J. 2010, 16: 463-

    CAS  PubMed  Google Scholar 

  38. Shalaby S, Kabbash I, El Saleet G, Mansour N, Omar A, El Nawawy A: Hepatitis B and C viral infection: prevalence, knowledge, attitude and practice among barbers and clients in Gharbia governorate, Egypt. East Mediterr Health J. 2007, 16: 10-17.

    Google Scholar 

  39. Saleem F, Hassali MA, Shafie AA, Awad AG, Bashir S: Association between knowledge and drug adherence in patients with hypertension in Quetta, Pakistan. Trop J Pharm Res. 2011, 10: 125-132.

    Google Scholar 

  40. Razi A, Ur Rehman R, Naz S, Ghafoor F, Khan MAU: Knowledge attitude and practices of university students regarding hepatitis B and C. ARPN Journal of Agricultural and Biological Science. 2010, 5: 38-43.

    Google Scholar 

  41. Kabir A, Tabatabaei SV, Khaleghi S, Agah S, Kashani AHF, Moghimi M, Kerahroodi FH, Alavian SH, Alavian SM: Knowledge, attitudes and practice of iranian medical specialists regarding hepatitis B and C. Hepat Mon. 2010, 10: 176-182.

    PubMed  PubMed Central  Google Scholar 

  42. Cheung J, Lee TK, Teh CZ, Wang C, Kwan W, Yoshida EM: Cross-sectional study of hepatitis B awareness among Chinese and Southeast Asian Canadians in the Vancouver-Richmond community. Can J Gastroenterol. 2005, 19: 245-249.

    Article  PubMed  Google Scholar 

  43. Singh A, Purohit B: Knowledge, Attitude and Practice towards Infection Control Measures and it’s Correlation among Dental Students in Bhopal city, Central India. International Journal of Infection Control. 2011, 7: doi: 10.3396/ijic.V7i1.007.11.

    Google Scholar 

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The authors acknowledge the respondents for participating in the study.

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Correspondence to Noman ul Haq.

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The authors have declared no competing interests. No funding was received for this study.

Authors’ contribution

NUH and FS conducted the survey and drafted the initial manuscript. MAH and AAS designed and supervised the study. MF and HA helped in statistical analysis, interpretation and manuscript revision. All authors read and approved the final manuscript.

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ul Haq, N., Hassali, M.A., Shafie, A.A. et al. A cross sectional assessment of knowledge, attitude and practice towards Hepatitis B among healthy population of Quetta, Pakistan. BMC Public Health 12, 692 (2012).

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  • Knowledge
  • Attitude
  • Practice
  • Hepatitis B
  • Healthy population
  • Pakistan