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Table 5 The associations of study variables with incidence of stroke using survival and longitudinal models stratified by sex

From: The effect of obesity phenotype changes on cardiovascular outcomes in adults older than 40 years in the prospective cohort of the Tehran lipids and glucose study (TLGS): joint model of longitudinal and time-to-event data

Stroke from Bayesian Cox model

  

Male(2892)

Female (3458)

Variables

 

HR (95% CI)

P-value

HR (95% CI)

P-value

Education (Reference: illiterate)

Literate

1.20 (0.77 to 1.87)

0.40

0.50 (0.34 to 0.74)

<0.001

Smoking status (Reference: Never smoker)

Past smoker

1.18 (0.82 to 1.71)

0.35

2.59 (1.31 to 5.13)

0.005

 

Current smoker

1.35 (0.87 to 2.08)

0.17

1.39 (0 to inf)

0.99

Physical activity (Reference: Highest)

Lowest

0.88 (0.65 to 1.19)

0.43

1.22 (0.87 to 1.71)

0.24

Family history of diabetes (Reference: No)

Yes

1.62 (1.17 to 2.25)

0.003

1.46 (1.04 to 2.05)

0.02

Family history of CVD (Reference: No)

Yes

1.09 (0.70 to 1.68)

0.69

1.39 (0.94 to 2.06)

0.09

Obesity phenotypes (Reference: Normal)

Abnormal

1.56 (1.01 to 2.41)

0.04

2.68 (0.98 to 7.27)

0.05

Age (year)

 

1.09 (1.07 to 1.11)

<0.001

1.09 (1.06 to 1.11)

<0.001

Obesity varying from Bayesian logit mixed effects model

  

Male (2892)

Female (3458)

Variables

 

OR (95% CI)

P-value

OR (95% CI)

P-value

Education (Reference: illiterate)

Literate

-

-

-

-

Smoking status (Reference: Never smoker)

Past smoker

0.63 (0.41 to 0.96)

0.03

1.15 (0.26 to 5.07)

0.85

 

Current smoker

0.30 (0.20 to 0.44)

<0.001

0.43 (0.16 to 1.16)

0.09

Physical activity (Reference: Highest)

Lowest

1.62 (1.18 to 2.21)

0.002

1.02 (0.68 to 1.53)

0.88

Family history of diabetes (Reference: No)

Yes

3.09 (2.12 to 4.52)

<0.001

1.61 (1.02 to 2.55)

0.03

Family history of CVD (Reference: No)

Yes

1.006 (0.63 to 1.59)

0.97

1.73 (0.93 to 3.21)

0.08

Obesity phenotypes (Reference: Normal)

Normal

-

-

-

-

Age (year)

 

1.03 (1.01 to 1.05)

<0.001

1.17 (1.15 to 1.18)

<0.001

  1. Abbreviations CVD: Cardiovascular disease; CI: credible interval; HR: hazard ratio; OR: odds ratio