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Table 1 Infancy period (within 1 year) risk factors for Crohn’s disease (CD) and ulcerative colitis (UC) in crude analysis

From: Pregnancy period and early-life risk factors for inflammatory bowel disease: a Northern Finland birth cohort 1966 study

 

CD

UC

n = 41, %

OR (95% CI)

n = 113, %

OR (95% CI)

Breast feeding at least 1 month*

Yes, n = 2996

11, 0.37

0.18 (0.08–0.45)

54, 1.80

1.18 (0.53–2.61)

No, n = 457

9, 1.97

 

7, 1.53

 

Vitamin D supplementation**

Yes, n = 5517

29, 0.53

0.46 (0.21–1.02)

95, 1.72

0.93 (0.52–1.69)

No, n = 710

8, 1.13

 

13, 1.83

 

Iron supplementation***

Yes, n = 3603

13, 0.36

0.41 (0.20–0.81)

56, 1.53

0.80 (0.54–1.18)

No, n = 2488

22, 0.88

 

48, 1.93

 

DTP vaccination

Yes, n = 5647

29, 0.51

0.45 (0.21–1.00)

92, 1.63

0.72 (0.42–1.23)

No, n = 712

8, 1.12

 

16, 2.25

 

Polio vaccination

Yes, n = 5038

26, 0.52

0.58 (0.29–1.18)

81, 1.61

0.77 (0.49–1.20)

No, n = 1247

11, 0.88

 

26, 2.00

 

Smallpox vaccination

Yes, n = 962

7, 0.73

1.25 (0.55–2.86)

22, 2.29

1.51 (0.93–2.44)

No, n = 4977

29, 0.58

 

76, 1.53

 

Antibiotics during first year

Yes, n = 3218

16, 0.50

0.75 (0.38–1.46)

53, 1.65

0.92 (0.63–1.36)

No, n = 2862

19, 0.66

 

51, 1.78

 
  1. DTP, diphtheria, tetanus and pertussis vaccination ≥ 3 times
  2. polio vaccination ≥ 2 times
  3. *Information available, n = 3453
  4. ** Regular vitamin D supplementation
  5. *** Regular iron supplementation