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Table 2 Logistic regression analysis of log10-transformed blood furan levels for the risk of COPD

From: Inflammation mediates the association between furan exposure and the prevalence and mortality of chronic obstructive pulmonary disease: National Health and Nutrition Examination Survey 2013–2018

Blood furan

Crude Model

Model I

Model II

OR (95% CI)

P-value

OR (95% CI)

P-value

OR (95% CI)

P-value

Log10-transformed blood furan

6.00 (3.58–10.05)

< 0.001

3.14 (1.64–5.99)

< 0.001

4.70 (1.58–13.94)

0.007

Q1 group

Reference

Reference

Reference

Q2 group

1.75 (0.78–3.89)

0.168

1.40 (0.61–3.22)

0.417

2.09 (0.70–6.28)

0.181

Q3 group

2.29 (1.32–3.99)

0.004

1.54 (0.85–2.80)

0.147

3.10 (1.29–7.41)

0.013

Q4 group

2.50 (1.32–4.74)

0.006

1.54 (0.75–3.14)

0.230

3.03 (1.13–8.08)

0.028

Q5 group

6.11 (3.71–10.05)

< 0.001

3.35 (1.85–6.07)

< 0.001

4.47 (1.58–12.66)

0.006

P for trend

< 0.001

< 0.001

0.001

  1. The crude model lacked adjustments for covariates. Model I incorporated cotinine adjustments. Model II included adjustments for cotinine, age, gender, marital status, ethnicity, educational attainment, past-year alcohol drinking, and BMI. Abbreviations: COPD, chronic obstructive pulmonary disease; OR, odd ratio; CI, confidence interval