Table 2 Associations between sleep problems and abnormal CVD biomarkers in the U.S. adult population, NHANES 2007–2018

Abnormal CRP (n = 6,371)

Crude model

3.35 (1.26–8.90) **

Ref

7.21 (2.39–21.73) **

Ref

1.49 (0.55–4.05)

Adjusted model ³

3.08 (1.18–8.05) **

Ref

6.12 (2.19–17.15) **

Ref

1.32 (0.45–3.85)

Abnormal HDL (n = 23,445)

Crude model

1.33 (1.18–1.50) **

Ref

0.99 (0.81–1.20)

Ref

0.90 (0.80-1.00)

Adjusted model ³

1.20 (1.05–1.39) *

Ref

0.99 (0.81–1.20)

Ref

0.96 (0.83–1.12)

Abnormal LDL (n = 10,995)

Crude model

1.01 (0.91–1.13)

Ref

0.87 (0.72–1.04)

Ref

1.09 (0.96–1.23)

Adjusted model ³

0.98 (0.87–1.10)

Ref

0.92 (0.76–1.12)

Ref

0.97 (0.84–1.11)

Abnormal TG (n = 11,161)

Crude model

1.14 (0.98–1.31)

Ref

1.08 (0.92–1.26)

Ref

1.31 (1.14–1.50) **

Adjusted model ³

1.11 (0.95–1.29)

Ref

1.11 (0.94–1.30)

Ref

1.18 (1.01–1.37) *

Abnormal HbA1c (n = 23,710)

Crude model

1.40 (1.18–1.67) **

Ref

1.60 (1.22–2.11) **

Ref

1.40 (1.16–1.70) **

Adjusted model ³

1.25 (1.05–1.49) **

Ref

1.54 (1.09–2.17) **

Ref

1.16 (0.95–1.42)

Abnormal Glucose (n = 11,410)

Crude model

1.18 (1.00-1.40) **

Ref

1.46 (1.13–1.88) **

Ref

1.45 (1.22–1.72) **

Adjusted model ³

1.09 (0.91–1.29)

Ref

1.45 (1.07–1.95) *

Ref

1.24 (1.04–1.49) *

Abnormal Insulin (n = 6,082)

Crude model

1.32 (1.12–1.55) **

Ref

1.26 (0.99–1.62)

Ref

1.32 (1.13–1.53) **

Adjusted model ³

1.24 (1.03–1.51) *

Ref

1.25 (0.89–1.77)

Ref

1.09 (0.91–1.31)