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Table 1 Baseline characteristics of those authorized for medical cannabis and matched controls (n = 19,380)

From: Benzodiazepine use in medical cannabis authorization adult patients from 2013 to 2021: Alberta, Canada

Characteristic

Controls

(N = 9690)

Authorized for medical cannabis

(N = 9690)

p-value

Standardized Difference

Age, years, mean (SD)

53.7 (14.5)

54.4 (13.9)

0.06

0.04815

Female, n (%)

6147 (63.4%)

6170 (63.7%)

0.74

0.04815

Rural, n (%)

1235 (12.8%)

1251 (12.9%)

0.75

0.00494

Age group

    

< 35

1060 (10.9%)

1040 (10.7%)

0.66

−0.00664

35–50

2426 (25.0%)

2346 (24.2%)

0.18

−0.01916

50–65

4046 (41.8%)

3907 (40.3%)

0.05

−0.02916

> 65

2158 (22.3%)

2397 (24.7%)

< 0.01

0.05819

Social material deprivation index:

 1

1889 (19.5%)

1768 (18.3%)

0.03

−0.03192

 2

1848 (19.1%)

1921 (19.8%)

0.19

0.01903

 3

1693 (17.5%)

1788 (18.5%)

0.08

0.02554

 4

2033 (21.0%)

2127 (21.9%)

0.10

0.02363

 5

2227 (23.0%)

2086 (21.5%)

0.02

−0.03499

Medications

 Benzo durations, mean (SD)

0.82 (0.21)

0.82 (0.21)

0.87

0.00005

 Antiepileptics

5140 (53.0%)

5038 (52.0%)

0.14

−0.02108

 Anti-Parkinson drugs

387 (4%)

394 (4.1%)

0.80

0.00367

 Psycholeptics

9153 (94.5%)

9155 (94.5%)

0.97

0.00090

 Psychoanaleptics

7089 (73.2%)

6934 (71.6%)

0.01

−0.03577

 Other nervous system drugs

1146 (11.8%)

1086 (11.2%)

0.18

−0.01940

Comorbidities

 Neoplasms, n (%)

2104 (21.7%)

2241 (23.1%)

0.02

0.03391

 Diabetes, n (%)

1387 (14.3%)

1239 (12.8%)

0.01

−0.04464

 Mental Disorder, n (%)

8002 (82.6%)

7910 (81.6%)

0.08

−0.02477

 Nerve System Disease, n (%)

2449 (25.3%)

2704 (27.9%)

< 0.01

0.05959

 Chronic Obstructive Pulmonary Disease, n (%)

1813 (18.7%)

1723 (17.8%)

0.09

−0.02477

 Colitis, n (%)

197 (2.0%)

259 (2.7%)

< 0.01

0.04222

 Diseases of the Musculoskeletal System and Connective Tissue, n (%)

6863 (70.8%)

7221 (74.5%)

< 0.01

0.08298

 Injury and Poisoning, n (%)

2789 (28.8%)

2616 (27.0%)

0.01

−0.03982

Healthcare Utilization

 Patients with at least one inpatient hospitalization, n (%)

1654 (17.1%)

1621 (16.7%)

0.54

−0.00909

 Patients with at least five outpatient visits, n (%)

3893 (40.2%)

3824 (39.5%)

0.32

−0.01455

 Patients with at least five distinct drug class dispensations, n (%)

9376 (96.8%)

9331 (96.3%)

0.08

−0.02537