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Table 3 Threshold effect analysis of TyG index and OA

From: Association between higher triglyceride glucose index and increased risk of osteoarthritis: data from NHANES 2015–2020

Osteoarthritis

OR (95% CI)

p value

TyG index

  

Inflection point

 

9.67

TyG index < Inflection point

1.54 (1.24, 1.91)

0.0001

TyG index > Inflection point

0.28 (0.07, 1.14)

0.0746

Log-likelihood ratio

 

0.015

  1. Data are presented as OR, 95% CI, and p value
  2. Model 1: adjusted for nothing
  3. Model 2: adjusted for age, gender, and race
  4. Model 3: adjusted for age, gender, race, education level, PIR, smoke status, alcohol consumption, hypertension, diabetes, moderate physical activity, BMI, HDL cholesterol, LDL cholesterol, insulin, HOMA-IR, ALT, AST, CRP, BUN, and UA
  5. ALT: alanine transaminase; AST: aspartate aminotransferase; BMI: body mass index; BUN: blood urea nitrogen; CI: confidence interval; CRP: C-Reactive Protein; HDL cholesterol: high-Density Lipoprotein Cholesterol; HOMA-IR, homeostatic model assessment of insulin resistance; LDL cholesterol: low-Density Lipoprotein Cholesterol; OR: odds ratio; PIR:Poverty-to-income ratio; TyG: Triglyceride–Glucose; UA; uric acid