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Table 2 Association between TyG and OA

From: Association between higher triglyceride glucose index and increased risk of osteoarthritis: data from NHANES 2015–2020

 

OR (95% CI), p value

Model 1

Model 2

Model 3

Osteoarthritis

   

TyG index

9.52 (4.13, 21.92) < 0.0001

8.54 (3.41, 21.37) < 0.0001

7.34 (2.25, 23.93) 0.0010

Categories

   

Quartile 1

Reference

Reference

Reference

Quartile 2

1.26 (0.94, 1.68) 0.1217

1.15 (0.85, 1.56) 0.3523

1.12 (0.82, 1.54) 0.4760

Quartile 3

1.76 (1.34, 2.32) < 0.0001

1.60 (1.20, 2.14) 0.0015

1.62 (1.17, 2.25) 0.0036

Quartile 4

1.93 (1.47, 2.54) < 0.0001

1.76 (1.31, 2.35) 0.0002

1.69 (1.18, 2.42) 0.0039

P for trend

9.52 (4.13, 21.92) < 0.0001

1.49 (1.24, 1.79) < 0.0001

1.45 (1.16, 1.83) 0.0014

  1. Data are presented as ORs, 95% CIs, and P-value
  2. Model 1: adjusted for nothing
  3. Model 2: adjusted for age, gender, and race
  4. Model 3: adjusted for age, gender, race, education level, PIR, smoke status, alcohol consumption, hypertension, diabetes, moderate physical activity, BMI, HDL cholesterol, LDL cholesterol, insulin, HOMA-IR, ALT, AST, CRP, BUN, and UA
  5. ALT: alanine transaminase; AST: aspartate aminotransferase; BMI: body mass index; BUN: blood urea nitrogen; CI: confidence interval; CRP: C-Reactive Protein; HDL cholesterol: high-Density Lipoprotein Cholesterol; HOMA-IR, homeostatic model assessment of insulin resistance; LDL cholesterol: low-Density Lipoprotein Cholesterol; OR: odds ratio; PIR:Poverty-to-income ratio; TyG: Triglyceride–Glucose; UA; uric acid