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Table 1 Information on the Union-WHO framework

From: The collaborative framework for the management of tuberculosis and type 2 diabetes syndemic in low- and middle-income countries: a rapid review

Author, Year

Country Rural / Urban Public / Private

Study design

Study population

Findings

Barriers & Facilitators

Outcomes

Ekeke, 2017 [29],

Nigeria

Urban

Public & private

Cross-sectional

TB patients

T2D prevalence was 9.4%; Factors associated with T2D were: age > 40 years old, rural residence and private health facility care

Barriers: Diagnostic method used

Facilitators: Authors were able to implement the screening in a routine programme setting across multiple regions and facilities with minimal additional costs and training

Feasibility and effectiveness of T2D screening among TB patients

Shayo, 2019 [30]

Tanzania

Rural & Urban

Public & Private

Cross-sectional

Health facilities

Only 38.4% of all T2D facilities offer diagnosis and treatment for TB; The overall readiness of T2D facilities to provide TB services was low (12.6%); Public T2D facilities had comparatively higher availability of TB services than private ones

Barriers: Shortage of staff trained to co-manage TB in T2D care facilities; Inadequate TB management guidelines, medications, and diagnostics

Facilitators: Ministry of Health (MoH) has developed the guideline for TB-T2D collaborative care; NCDs strategic plan II prioritises to train healthcare providers on the collaborative TB-T2D care

Availability and readiness of TB management in T2D facilities

Salifu, 2020 [31]

Ghana

Public

Exploratory Qualitative

Healthcare workers (HCW)

Implementing bi-directional screening was achievable, when properly implemented; Screening to detect TB among T2D patients was more organised and focused; TB task-shifting officers improved T2D patients screening for TB

Barriers: Delays in screening; Fear and stigmatisation of TB; Poor collaboration between TB and T2D units; Skewed funding for screening

Facilitators: Increase in staff capacity; Institutionalisation of bidirectional screening

Co-management of TB-T2D comorbidity

Salifu, 2021 [17], [32]

Ghana

Public

Exploratory Qualitative

HCW

The study revealed 3 major themes: (1) Prioritisation of TB/HIV co-infection while negating TB-T2D comorbidity, (2) Poor working conditions, and (3) Coping mechanisms & 5 sub-themes: (1) Low knowledge and awareness on TB-T2D comorbidity, (2) Limited awareness of The Union-WHO framework among the HCW, (3) High workload in TB & T2D clinics, (4) Multiple roles, (5) Inadequate training and (6) Space shortage

Barriers: Prioritisation of TB-HIV co-infection while negating TB-T2D comorbidity, Poor working conditions, Low knowledge, and awareness on TB-T2D comorbidity, Limited awareness of The Union-WHO framework among the HCW, High workload in TB & T2D clinics, Multiple roles, Inadequate training, and Space shortage

Facilitators: Coping mechanisms

Co-management of TB-T2D comorbidity