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Table 3 Characteristics of the participants according to the quartile of relative leg extension strength

From: Association of physiological factors with grip and leg extension strength: tohoku medical megabank community-based cohort study

 

Quartile of leg extension strength (MEN)

Quartile of leg extension strength (WOMEN)

Q1

< 393 W

Q2

394–509 W

Q3

510–639 W

Q4

> 640 W

p-value

Q1

< 214 W

Q2

215–276 W

Q3

277–347 W

Q4

> 348 W

p-value

Age, years

65.7 (12.9)

61.4 (12.5)

55.9 (13.1)

46.6 (12.4)

< 0.0001

56.6 (14.8)

55.5 (13.4)

53.8 (12.7)

49.3 (12.2)

< 0.0001

GS, kg

36.7 (6.7)

40.6 (6.5)

43.2 (6.2)

47.6 (7.5)

< 0.0001

23.8 (4.3)

25.2 (4.3)

26.1 (4.2)

28.3 (4.5)

< 0.0001

Alcohol drinking status, n (%)

    

0.0036

    

< 0.0001

 Current-drinker

540 (75.4)

570 (79.4)

582 (81.4)

586 (82.3)

 

719 (42.5)

771 (45.5)

834 (50.2)

920 (55.0)

 

 Ex-drinker

32 (4.5)

16 (2.2)

21 (2.9)

9 (1.3)

 

27 (1.6)

24 (1.4)

21 (1.3)

32 (1.9)

 

 Never-drinker

143 (20.0)

132 (18.4)

112 (15.7)

117 (16.4)

 

944 (55.8)

896 (52.9)

805 (48.5)

720 (43.1)

 

 Unknown

1 (0.1)

0 (0)

0 (0)

0 (0)

 

1 (0.1)

2 (0.1)

1 (0.1)

0 (0)

 

Smoking status, n (%)

    

< 0.0001

    

< 0.0001

 Current-smoker

128 (17.9)

147 (20.5)

177 (24.8)

223 (31.3)

 

139 (8.2)

123 (7.3)

127 (7.6)

166 (9.9)

 

 Ex-smoker

349 (48.7)

358 (49.9)

364 (50.9)

288 (40.4)

 

184 (10.9)

212 (12.5)

262 (15.8)

299 (17.9)

 

 Never-smoker

237 (33.1)

211 (29.4)

174 (24.3)

201 (28.2)

 

1364 (80.7)

1355 (80.0)

1270 (76.5)

1202 (71.9)

 

 Unknown

2 (0.3)

2 (0.3)

0 (0)

0 (0)

 

4 (0.2)

3 (0.2)

2 (0.1)

5 (0.3)

 

Education status, n (%)

    

< 0.0001

    

< 0.0001

 <12 years

111 (15.5)

54 (7.5)

45 (6.3)

29 (4.1)

 

150 (8.9)

83 (4.9)

57 (3.4)

33 (2)

 

 12 years

362 (50.6)

354 (49.3)

321 (44.9)

289 (40.6)

 

867 (51.3)

846 (50.0)

787 (47.4)

765 (45.8)

 

 >12 years

229 (32.0)

299 (41.6)

335 (46.9)

391 (54.9)

 

653 (38.6)

751 (44.4)

809 (48.7)

862 (51.6)

 

 Others

5 (0.7)

3 (0.4)

7 (1.0)

1 (0.1)

 

7 (0.4)

2 (0.1)

5 (0.3)

5 (0.3)

 

 Unknown

9 (1.3)

8 (1.1)

7 (1.0)

2 (0.3)

 

14 (0.8)

11 (0.6)

3 (0.2)

7 (0.4)

 

Anthropometry

 Height, cm

164.8 (6)

166.8 (5.8)

168.8 (5.7)

172.1 (5.6)

< 0.0001

154.2 (5.8)

155.6 (5.4)

156.6 (5.3)

158.6 (5.3)

< 0.0001

 Weight, kg

63.6 (10.5)

65.6 (9.8)

67.8 (9.4)

72.1 (10.4)

< 0.0001

53.0 (9.0)

53.5 (8.7)

53.8 (8.4)

55.9 (8.5)

< 0.0001

 BMI, kg/cm2

23.4 (3.4)

23.5 (3.0)

23.8 (3.0)

24.3 (3.1)

< 0.0001

22.3 (3.6)

22.1 (3.4)

21.9 (3.3)

22.2 (3.2)

0.0018

 WC, cm

85.6 (9.3)

85.6 (8.3)

86.1 (8.2)

86.7 (8.7)

0.0660

81.4 (9.8)

81.1 (9.3)

80.6 (9.3)

80.9 (9.1)

0.0297

 %BFM, %

24.9 (6.4)

23.4 (6.0)

23.2 (6.1)

21.9 (6.1)

< 0.0001

31.2 (7.4)

30.6 (7.1)

29.8 (7.1)

29.3 (6.9)

< 0.0001

 Bone area ratio, %

27.7 (3.6)

28.2 (3.7)

28.7 (3.7)

29.7 (3.9)

< 0.0001

27.8 (4.2)

28.0 (4.2)

28.4 (4.1)

29.4 (4.3)

< 0.0001

Pulmonary function

 VC, L

3.6 (0.6)

3.9 (0.6)

4.1 (0.6)

4.6 (0.6)

< 0.0001

2.7 (0.5)

2.9 (0.5)

3.0 (0.5)

3.2 (0.5)

< 0.0001

 FVC, L

3.4 (0.6)

3.8 (0.6)

4.0 (0.6)

4.4 (0.6)

< 0.0001

2.7 (0.5)

2.8 (0.5)

2.9 (0.5)

3.1 (0.5)

< 0.0001

 FEV1, L

2.7 (0.6)

3.0 (0.6)

3.2 (0.6)

3.6 (0.6)

< 0.0001

2.2 (0.5)

2.3 (0.4)

2.4 (0.4)

2.5 (0.5)

< 0.0001

 FEV1/FVC, %

78.5 (7.5)

78.6 (7.6)

79.8 (6.4)

80.8 (5.7)

< 0.0001

81.4 (6.2)

81.7 (5.9)

81.6 (5.7)

82.2 (5.8)

0.0018

Blood pressure

 SBP, mmHg

138.6 (18.2)

135.3 (16.7)

134.1 (16.9)

130.6 (15.0)

< 0.0001

127.4 (18.7)

127.2 (18.5)

125.1 (18.3)

122.3 (17.9)

< 0.0001

 DBP, mmHg

80.7 (11.1)

81.8 (10.9)

83.3 (11.1)

82.4 (11.0)

0.0003

77.0 (10.6)

77.1 (10.6)

77.0 (10.8)

76.3 (11.1)

0.0740

Pulse rate, beat/min

65.8 (11.2)

64.0 (10.1)

65.4 (10.2)

65.3 (9.9)

0.0064

67.5 (9.5)

66.7 (9.3)

66.6 (9.4)

66.4 (9.5)

0.0047

CIMT, mm

0.7 (0.2)

0.7 (0.1)

0.6 (0.1)

0.6 (0.1)

< 0.0001

0.6 (0.1)

0.6 (0.1)

0.6 (0.1)

0.5 (0.1)

< 0.0001

Lipid markers

 TC, mg/dL

199.5 (32.5)

203.9 (33.6)

206.8 (36.8)

205.0 (36.0)

0.0007

211.4 (35.3)

213.3 (35.9)

214.8 (35.9)

209.6 (36.5)

0.0004

 Triglycerides, mg/dL

117.3 (81.0)

123.2 (91.6)

128.3 (116.7)

135.9 (116.5)

0.0027

95.0 (55.6)

95.2 (59.2)

92.1 (83.4)

86.7 (56.6)

0.0002

 HDL-C, mg/dL

57.6 (15.3)

57.7 (15.5)

56.9 (14.1)

56.7 (15.0)

0.4408

66.3 (15.9)

67.4 (15.6)

69.0 (16.1)

68.8 (16.5)

< 0.0001

Glucometabolic markers

 HbA1c, %

5.6 (0.5)

5.5 (0.5)

5.5 (0.5)

5.4 (0.4)

< 0.0001

5.4 (0.4)

5.4 (0.4)

5.4 (0.4)

5.4 (0.3)

< 0.0001

 Glucose, mg/dL

92.9 (18.5)

90.6 (14.7)

89.9 (16.0)

87.8 (12.7)

< 0.0001

87.3 (14.0)

85.7 (12.2)

85.2 (11.3)

84.0 (10.2)

< 0.0001

eGFR, ml/min/1.73 m2

90 (21.3)

95.6 (19.6)

102.6 (19.7)

110.8 (18.3)

< 0.0001

103.9 (24.0)

106.7 (22.4)

108.6 (21.9)

114.3 (22.2)

< 0.0001

Uric acid, mg/dL

5.7 (1.3)

5.9 (1.2)

6 (1.2)

6.1 (1.2)

< 0.0001

4.4 (1.0)

4.5 (1.0)

4.5 (1.0)

4.4 (1.0)

0.3058

Red blood cells count, 104/µL

468.1 (43.1)

475.7 (38.6)

482.8 (38.3)

491.4 (37.6)

< 0.0001

440.3 (33.2)

441.6 (33.0)

442.9 (31.6)

443.7 (31.7)

0.0095

Hemoglobin, g/dL

14.7 (1.3)

14.9 (1.1)

15.1 (1.1)

15.2 (1.0)

< 0.0001

13.2 (1.1)

13.2 (1.1)

13.3 (1.0)

13.2 (1.1)

0.6817

Hematocrit, %

44.2 (3.5)

44.8 (3.0)

45.3 (3.0)

45.5 (2.8)

< 0.0001

40.6 (3)

40.6 (3.0)

40.8 (2.8)

40.6 (2.9)

0.3917

  1. Data are expressed as mean (standard deviation) for continuous variables and number (percentage) for categorical variables
  2. GS: grip strength; BMI: body mass index; WC: waist circumference; %BFM; percentage body fat mass VC: vital capacity; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; CIMT: carotid intima-media thickness; HDL-C: high-density lipoprotein cholesterol; HbA1c: hemoglobin A1c; and eGFR: estimated glomerular filtration rate; Q: quartile
  3. The p-value was obtained using ANOVA for continuous variables and chi-square for categorical variables of proportion