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Table 3 Results of multivariable multinomial logistic regression analysis: determinants of pneumococcal vaccine uptake and hesitancy (expressed as delay vs. refusal) among respondents who answered on their own behalf (n = 2357)

From: Pneumococcal vaccine uptake among high-risk adults and children in Italy: results from the OBVIOUS project survey

Characteristic

Did get the vaccine

Would get the vaccine

Would not get the vaccine

Predicted

Discrete difference (Δ)

Predicted

Discrete difference (Δ)

Predicted

Discrete difference (Δ)

probability

Estimate

95% CI

probability

Estimate

95% CI

probability

Estimate

95% CI

Gender

         

 Male

40.6%

Ref.

 

34.4%

Ref.

 

25.0%

Ref.

 

 Female†

38.0%

−2.7

−5.8, 0.4

34.1%

−0.3

−3.9, 3.2

28.0%

3.0*

0.3, 5.8

Age group, y

         

 18–34

48.5%

Ref.

 

27.8%

Ref.

 

23.7%

Ref.

 

 35–44

51.3%

2.8

−4.0, 9.6

25.9%

−1.9

−9.2, 5.5

22.8%

−0.9

−7.3, 5.5

 45–54

35.9%

−12.6*

−19.4, −5.8

31.6%

3.8

−3.8, 11.4

32.5%

8.8*

2.4, 15.2

 55–64

30.4%

−18.1*

−24.9, − 11.3

39.5%

11.7*

4.0, 19.4

30.0%

6.4

0.0, 12.8

  ≥ 65

37.6%

−10.9*

− 16.9, − 4.9

36.7%

8.9*

2.2, 15.6

25.7%

2.0

−3.7, 7.8

NUTS statistical region

         

 Northwestern Italy

34.9%

Ref.

 

37.4%

Ref.

 

27.7%

Ref.

 

 Northeastern Italy

48.6%

13.7*

9.0, 18.4

26.8%

−10.7*

−15.9, −5.5

24.6%

−3.1

−7.2, 1.1

 Central Italy

42.7%

7.8*

3.2, 12.4

30.7%

−6.7*

−11.8, −1.6

26.6%

−1.1

−5.0, 2.8

 Southern Italy

37.6%

2.7

−1.7, 7.1

37.8%

0.4

−4.6, 5.4

24.6%

−3.1

−6.9, 0.6

 Insular Italy

32.7%

−2.2

−7.8, 3.4

38.0%

0.6

−5.9, 7.1

29.3%

1.6

−3.4, 6.6

Degree of urbanization‡

         

 City

39.3%

Ref.

 

35.4%

Ref.

 

25.2%

Ref.

 

 Town or suburb

39.7%

0.4

−3.0, 3.7

34.1%

−1.3

−5.0, 2.5

26.2%

0.9

−2.0, 3.9

 Rural area

39.1%

−0.3

−5.2, 4.6

30.5%

−4.9

−10.5, 0.7

30.4%

5.2*

0.7, 9.7

Educational attainment

         

 Post-graduate/Doctorate degree

45.2%

Ref.

 

31.5%

Ref.

 

23.3%

Ref.

 

 Academic degree

40.1%

−5.1

−11.2, 1.1

35.9%

4.4

−2.6, 11.5

23.9%

0.6

−5.2, 6.5

 High school diploma

38.9%

−6.3*

−12.0, −0.6

34.3%

2.9

−3.6, 9.3

26.7%

3.4

−1.9, 8.8

 Less than high school diploma

36.6%

−8.6*

−15.3, − 1.8

34.1%

2.6

−5.0, 10.3

29.2%

5.9*

0.0, 11.9

Pneumopathy

         

 No

38.0%

Ref.

 

33.7%

Ref.

 

28.3%

Ref.

 

 Yes

44.2%

6.2*

1.9, 10.6

36.6%

2.9

−2.2, 8.0

19.2%

−9.1*

−13.0, −5.2

Cardiopathy

         

 No

38.0%

Ref.

 

33.6%

Ref.

 

28.4%

Ref.

 

 Yes

44.0%

6.0*

2.1, 9.9

36.4%

2.8

−1.7, 7.3

19.6%

−8.8*

−12.2, −5.3

Diabetes

         

 No

37.5%

Ref.

 

34.4%

Ref.

 

28.1%

Ref.

 

 Yes

44.2%

6.8*

2.9, 10.7

34.2%

−0.3

−4.7, 4.2

21.6%

−6.5*

−10.0, −3.1

Worry about pneumococcal pneumonia

         

 Very worried

51.0%

Ref.

 

32.3%

Ref.

 

16.7%

Ref.

 

 Quite worried

41.5%

−9.5*

−17.5, −1.5

45.0%

12.7*

3.2, 22.1

13.6%

−3.2

−12.2, 5.9

 A little worried

38.4%

−12.6*

−20.5, −4.7

35.6%

3.3

−6.0, 12.5

26.0%

9.3*

0.4, 18.3

 Not worried

36.6%

−14.4*

−22.7, −6.2

21.0%

−11.3*

−20.9, −1.7

42.5%

25.8*

16.3, 35.2

Perception of vaccine safety

         

 Very safe

46.9%

Ref.

 

40.5%

Ref.

 

12.6%

Ref.

 

 Quite safe

39.0%

−7.9*

−12.5, −3.3

37.0%

−3.5

−8.8, 1.7

24.0%

11.4*

7.5, 15.4

 Quite/Very unsafe

29.7%

−17.3*

−24.1, − 10.4

17.0%

−23.5*

−30.5, −16.4

53.3%

40.7*

34.1, 47.3

Dear ones’ views on vaccination in general

         

 Very favorable

41.0%

Ref.

 

40.4%

Ref.

 

18.5%

Ref.

 

 Favorable

41.5%

0.4

−3.9, 4.7

35.3%

−5.2*

−10.1, −0.3

23.3%

4.8*

1.0, 8.5

 Quite favorable

37.1%

−4.0

−8.5, 0.6

32.1%

−8.4*

−13.5, − 3.3

30.8%

12.3*

8.3, 16.4

 Quite unfavorable

36.0%

−5.1

−11.8, 1.7

25.8%

−14.7*

−22.2, −7.1

38.2%

19.7*

13.6, 25.9

 Unfavorable/Very unfavorable

42.1%

1.1

−6.3, 8.4

28.5%

−12.0*

−20.2, −3.7

29.4%

10.9*

4.8, 17.0

Awareness of having priority for vaccination

         

 Yes

59.3%

Ref.

 

27.6%

Ref.

 

13.1%

Ref.

 

 No

18.7%

−40.5*

−45.7, −35.4

39.0%

11.4*

5.4, 17.3

42.3%

29.2*

24.1, 34.2

 Don’t know

21.5%

−37.8*

−41.9, − 33.6

46.3%

18.6*

14.3, 23.0

32.2%

19.1*

15.8, 22.4

Perceived ease of access to get the vaccine

         

 Very easy

45.3%

Ref.

 

27.1%

Ref.

 

27.5%

Ref.

 

 Quite easy

37.9%

−7.4*

−11.9, −2.9

34.2%

7.1*

1.9, 12.2

27.9%

0.4

−4.3, 5.0

 Quite/Very difficult

37.1%

−8.2*

−13.9, −2.6

40.5%

13.4*

7.0, 19.7

22.4%

−5.1*

−10.2, 0.0

  1. NUTS, Nomenclature of Territorial Units for Statistics
  2. †Including non-binary people
  3. ‡According to the Eurostat Degree of Urbanization (DEGURBA) classification system
  4. *P-value ≤0.05, that is, Δ significantly ≠0