Table 2 The associations of HOMA2-IR with all-cause mortality in study participants
HOMA2-IR | Events, n (%) | HR (95% CI), P value | |||||
|---|---|---|---|---|---|---|---|
Model 1 | Model2 | Model3 | |||||
All-cause mortality All participants | |||||||
Per SD | 1666(23.5%) | 1.21(1.13–1.29) | < 0.001 | 1.21(1.13–1.28) | < 0.001 | 1.15(1.07–1.24) | < 0.001 |
Tertile 1 | 519(22.0%) | Ref. | Ref. | Ref. | |||
Tertile 2 | 520(22.2%) | 1.01(0.86–1.19) | 0.890 | 1.03(0.88–1.22) | 0.682 | 0.96(0.81–1.13) | 0.606 |
Tertile 3 | 627(26.4%) | 1.14(0.96–1.36) | 0.133 | 1.17(0.99–1.39) | 0.065 | 0.94(0.79–1.13) | 0.540 |
P for trend | 0.127 | 0.063 | 0.544 | ||||
BMI < 25 kg/m2 | |||||||
Per SD | 506(22.6%) | 1.16(1.02–1.31) | 0.019 | 1.15(1.03–1.29) | 0.014 | 1.14(1.04–1.26) | 0.007 |
Tertile 1 | 159(21.5%) | Ref. | Ref. | Ref. | |||
Tertile 2 | 147(19.9%) | 0.88(0.63–1.23) | 0.452 | 0.91(0.64–1.29) | 0.598 | 1.06(0.73–1.54) | 0.745 |
Tertile 3 | 200(26.2%) | 1.05(0.79–1.40) | 0.749 | 1.07(0.79–1.46) | 0.653 | 1.19(0.83–1.70) | 0.337 |
P for trend | 0.611 | 0.547 | 0.309 | ||||
25 ≤ BMI < 30 kg/m2 | |||||||
Per SD | 621(24.4%) | 1.18(1.08–1.28) | < 0.001 | 1.15(1.04–1.26) | 0.006 | 1.12(1.00-1.25) | 0.061 |
Tertile 1 | 184(22.1%) | Ref. | Ref. | Ref. | |||
Tertile 2 | 190(22.4%) | 1.13(0.87–1.46) | 0.366 | 1.07(0.84–1.36) | 0.564 | 1.06(0.82–1.38) | 0.639 |
Tertile 3 | 247(28.6%) | 1.13(0.88–1.46) | 0.326 | 1.08(0.86–1.37) | 0.511 | 0.97(0.77–1.23) | 0.818 |
P for trend | 0.350 | 0.529 | 0.795 | ||||
BMI ≥ 30 kg/m2 | |||||||
Per SD | 539(23.5%) | 1.27(1.14–1.42) | < 0.001 | 1.26(1.14–1.38) | < 0.001 | 1.12(1.01–1.25) | 0.031 |
Tertile 1 | 174(22.9%) | Ref. | Ref. | Ref. | |||
Tertile 2 | 153(19.9%) | 0.75(0.56-1.00) | 0.048 | 0.73(0.56–0.96) | 0.024 | 0.68(0.52–0.89) | 0.005 |
Tertile 3 | 212(27.6%) | 1.30(0.99–1.73) | 0.064 | 1.27(0.97–1.66) | 0.080 | 0.92(0.71–1.20) | 0.538 |
P for trend | 0.052 | 0.065 | 0.645 | ||||