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Table 5 Stratification analysis of type and frequency of fish intake during pregnancy on allergic diseases in six-month-old infants by prenatal mercury exposure

From: Infantile allergic diseases: a cohort study prenatal fish intake and mercury exposure context

Fish intake frequency (times/week)

Early pregnancy Mercury

Late pregnancy Mercury

Cord blood mercury

< 50th percentile (n = 294)

≥ 50th percentile (n = 296)

< 50th percentile (n = 295)

≥ 50th percentile(n = 295)

< 50th percentile (n = 294)

≥ 50th percentile (n = 296)

HR (95% C.I.)

HR (95% C.I.)

HR (95% C.I.)

HR (95% C.I.)

HR (95% C.I.)

HR (95% C.I.)

All type of fish

< 1

1.00 (ref.)

1.00 (ref.)

1.00 (ref.)

1.00 (ref.)

1.00 (ref.)

1.00 (ref.)

Total fish

≥ 1

0.86 (0.70,1.82)

0.93 (0.60,1.42)

0.82 (0.78,1.94)

0.95 (0.56,1.45)

0.75 (0.81,1.95)

0.83 (0.51,1.34)

White fish

≥ 1

0.68 (0.32,1.45)

0.57 (0.30,1.09)

0.73 (0.33,1.60)

0.64 (0.34,1.23)

0.62 (0.55,2.17)

0.44 (0.21,0.92)*

Blue fish

≥ 1

0.76 (0.59,2.63)

0.45 (0.21,0.96)

0.95 (0.49,2.25)

1.02 (0.26,1.22)

0.89 (0.47,2.15)

0.58 (0.28,1.23)

Shell fish

≥ 1

0.97 (0.62,3.65)

0.50 (0.18,1.41)

0.89 (0.30,2.40)

1.10 (0.30,1.91)

0.62 (0.19,2.05)

0.99 (0.43,2.27)

  1. Hazard ratio (HR) and 95% confidence intervals (C.I.) was estimated using Cox regression model adjusted for mother’s age, education, parity, pre-pregnancy BMI, parental allergy history, gender of the child, secondhand-smoke exposure, colostrum and breastfeeding
  2. *p-value < 0.05