Infantile allergic diseases: a cohort study prenatal fish intake and mercury exposure context

BMC Public Health

Table 4 Effect of type and frequency of prenatal fish intake and prenatal mercury exposure on allergic disease in six-month-old infant in multiple model

Allergic diseases in infants
Mother’s Fish intake frequency in pregnancy (times/week)		Multiple model with early pregnancy mercury**	p-value for interaction^¶	Multiple model with late pregnancy mercury**	p-value for interaction^¶	Multiple model with cord blood mercury**	p-value for interaction^¶
Mother’s Fish intake frequency in pregnancy (times/week)		OR (95% C.I.) †	p-value for interaction^¶	OR (95% C.I.) †	p-value for interaction^¶	OR (95% C.I.) †	p-value for interaction^¶
All type of fish	< 1	1.00 (ref.)		1.00 (ref.)		1.00 (ref.)
Total Fish	≥ 1	0.76 (0.51,1.12)	0.99	0.79 (0.53,1.16)	0.93	0.79 (0.53,1.16)	0.12
White fish	≥ 1	0.52 (0.29,0.92)*	0.63	0.54 (0.30,0.95)*	0.57	0.54 (0.31,0.93)*	0.03*
Blue fish	≥ 1	0.70 (0.38,1.31)	0.71	0.73 (0.40,1.36)	0.86	0.74 (0.40,1.37)	0.17
Shell fish	≥ 1	0.76 (0.34,1.70)	0.21	0.76 (0.34,1.71)	0.78	0.78 (0.35,1.76)	0.46

Odds ratio (OR) and 95% confidence intervals (C.I.) estimated using logistic regression model
† Adjusted for mother’s age, education, parity, pre-pregnancy BMI, parental allergy history, gender of the child, secondhand-smoke exposure, colostrum and breastfeeding
*p-value < 0.05; ** Multiple model include both: fish intake and mercury level in one model. ^¶ Multiplicative interaction between prenatal fish intake and mercury concentration

ISSN: 1471-2458