Table 1 Death, incident cases, and disability-adjusted life years (DALYs) for cirrhosis and other chronic liver diseases in 2019 and percentage change in age-standardized rates (ASRs) per 100,000 population from 1990 to 2019 by Global Burden of Disease regions

Global

1,472,011

(1,374,608 to 1,578,731)

18.00

(16.80 to 19.31)

-0.26

(-0.32 to -0.20)

2,051,553

(1,661,430 to 2,478,127)

25.35

(20.78 to 30.44)

-0.01

(-0.04 to 0.03)

46,189,415

(43,027,109 to 49,551,291)

560.43

(521.86 to 602.02)

-0.27

(-0.32 to -0.19)

Sex

 Male

969,067

(899,212 to 1,045,344)

24.81

(23.07 to 26.75)

-0.26

(-0.32 to -0.18)

1,206,124

(964,222 to 1,464,589)

29.67

(23.86 to 35.98)

-0.01

(-0.05 to 0.03)

31,781,079

(29,366,251 to 34,438,138)

783.31

(723.85 to 849.07)

-0.26

(-0.32 to -0.18)

 Female

502,944

(459,201 to 550,914)

11.70

(10.68 to 12.81)

-0.28

(-0.34 to -0.20)

845,429

(687,513 to 1,016,947)

20.91

(17.22 to 25.15)

-0.01

(-0.04 to 0.04)

14,408,336

(13,159,620 to 15,759,495)

343.96

(313.74 to 376.74)

-0.29

(-0.36 to -0.21)

Regions

 Andean Latin America

14,051

(11,229 to 17,327)

25.08

(20.08 to 30.92)

-0.20

(-0.40 to 0.06)

19,973

(17,614 to 22,665)

32.25

(28.40 to 36.69)

0.39

(0.28 to 0.50)

373,058

(294,137 to 465,085)

639.08

(506.08 to 795.50)

-0.31

(-0.49 to -0.06)

 Australasia

2511

(2297 to 2731)

5.48

(5.05 to 5.93)

-0.22

(-0.28 to -0.16)

3314

(2795 to 3818)

10.26

(8.75 to 11.72)

-0.08

(-0.14 to -0.01)

63,252

(58,693 to 67,741)

153.41

(142.81 to 164.14)

-0.25

(-0.30 to -0.19)

 Caribbean

9545

(7776 to 11,408)

18.52

(15.04 to 22.19)

-0.20

(-0.33 to -0.05)

10,842

(9201 to 12,553)

21.85

(18.56 to 25.08)

0.08

(0.03 to 0.13)

278,278

(219,587 to 341,080)

545.75

(429.14 to 672.58)

-0.22

(-0.36 to -0.08)

 Central Asia

33,909

(30,488 to 37,737)

42.86

(38.53 to 47.51)

0.55

(0.39 to 0.73)

58,160

(51,498 to 64,782)

59.06

(52.30 to 66.01)

0.80

(0.73 to 0.89)

1,173,144

(1,054,257 to 1,309,148)

1318.24

(1187.00 to 1467.06)

0.55

(0.40 to 0.74)

 Central Europe

33,596

(29,317 to 37,899)

17.71

(15.42 to 20.04)

-0.21

(-0.31 to -0.11)

37,555

(33,208 to 41,704)

29.11

(25.85 to 32.45)

-0.11

(-0.15 to -0.08)

964,512

(839,764 to 1,091,670)

554.84

(483.06 to 627.72)

-0.22

(-0.31 to -0.12)

 Central Latin America

68,062

(58,609 to 78,330)

28.32

(24.45 to 32.59)

-0.22

(-0.32 to -0.10)

106,174

(85,022 to 127,867)

40.76

(32.74 to 48.98)

-0.05

(-0.12 to 0.04)

2,031,944

(1,740,913 to 2,343,602)

816.65

(700.77 to 940.38)

-0.26

(-0.37 to -0.15)

 Central Sub-Saharan Africa

22,757

(17,088 to 29,114)

36.98

(27.96 to 47.37)

-0.29

(-0.47 to -0.08)

30,833

(25,653 to 36,783)

26.97

(21.49 to 33.11)

0.19

(0.11 to 0.30)

843,049

(629,421 to 1,106,949)

1089.72

(821.03 to 1392.66)

-0.28

(-0.47 to -0.04)

 East Asia

164,719

(140,148 to 191,748)

8.18

(7.01 to 9.46)

-0.58

(-0.65 to -0.48)

424,355

(321,444 to 529,848)

22.51

(17.71 to 27.56)

-0.18

(-0.24 to -0.08)

4,698,613

(3,982,096 to 5,513,225)

227.88

(193.82 to 266.21)

-0.61

(-0.68 to -0.51)

 Eastern Europe

72,717

(64,994 to 81,005)

24.29

(21.67 to 27.04)

1.29

(1.04 to 1.55)

66,873

(47,654 to 90,004)

31.27

(23.38 to41.10)

0.57

(0.36 to 0.80)

2,575,334

(2,298,784 to 2,874,694)

919.51

(820.66 to 1026.76)

1.71

(1.43 to 2.02)

 Eastern Sub-Saharan Africa

76,980

(66,309 to 91,419)

44.15

(38.47 to 51.91)

-0.25

(-0.39 to -0.07)

86,022

(67,755 to 105,518)

27.15

(19.80 to 35.41)

0.07

(0.03 to 0.13)

2,608,125

(2,191,259 to 3,151,158)

1178.42

(1015.50 to 1402.45)

-0.28

(-0.44 to -0.06)

 High-income Asia Pacific

36,888

(32,213 to 41,082)

8.69

(7.87 to 9.38)

-0.58

(-0.61 to -0.54)

50,826

(41,597 to 60,069)

25.15

(21.29 to 29.18)

-0.36

(-0.41 to -0.29)

776,896

(717,257 to 824,271)

230.17

(216.01 to 242.91)

-0.62

(-0.64 to -0.58)

 High-income North America

72,738

(69,312 to 75,464)

12.67

(12.16 to 13.11)

0.04

(0.01 to 0.08)

98,636

(81,095 to 116,829)

25.62

(21.47 to 30.08)

0.09

(-0.01 to 0.23)

1,955,333

(1,892,680 to 2,014,258)

371.36

(360.22 to 381.81)

0.00

(-0.03 to 0.03)

 North Africa and Middle East

109,706

(81,390 to 135,204)

27.73

(21.06 to 33.88)

-0.37

(-0.53 to -0.21)

160,139

(133,538 to 190,699)

28.68

(23.58 to 34.88)

0.21

(0.14 to 0.29)

2,878,426

(2,126,424 to 3,565,003)

616.80

(457.71 to 761.65)

-0.37

(-0.54 to -0.20)

 Oceania

1152

(905 to 1445)

13.19

(10.56 to 16.35)

-0.20

(-0.38 to -0.01)

1123

(935 to 1323)

8.50

(7.05 to 10.00)

-0.13

(-0.18 to -0.08)

45,977

(35,984 to 57,692)

440.77

(347.93 to 550.45)

-0.21

(-0.39 to 0.00)

 South Asia

348,393

(306,924 to 404,845)

23.49

(20.74 to 27.13)

-0.24

(-0.35 to -0.10)

413,984

(299,626 to 539,338)

22.98

(16.68 to 29.92)

0.33

(0.25 to 0.41)

12,436,281

(10,954,316 to 14,414,136)

750.60

(662.20 to 867.89)

-0.24

(-0.35 to -0.10)

 Southeast Asia

186,154

(165,361 to 207,697)

30.21

(26.88 to 33.49)

-0.27

(-0.38 to -0.15)

181,538

(142,578 to 219,743)

24.76

(19.50 to 30.00)

-0.06

(-0.13 to 0.04)

5,915,348

(5,207,218 to 6,642,922)

866.96

(765.10 to 970.68)

-0.33

(-0.42 to -0.22)

 Southern Latin America

14,153

(13,221 to 15,117)

17.34

(16.22 to 18.49)

-0.23

(-0.28 to -0.18)

22,198

(19,634 to 24,756)

30.50

(27.07 to 34.08)

0.18

(0.10 to 0.26)

372,367

(351,788 to 394,658)

471.63

(446.43 to 499.36)

-0.30

(-0.34 to -0.26)

 Southern Sub-Saharan Africa

9230

(8229 to 10,319)

15.43

(13.82 to 17.16)

-0.32

(-0.49 to -0.14)

12,183

(9241 to 15,402)

15.57

(11.70 to 19.87)

-0.19

(-0.23 to -0.14)

310,793

(272,943 to 353,505)

458.73

(405.32 to 516.57)

-0.36

(-0.51 to -0.20)

 Tropical Latin America

38,778

(36,545 to 41,257)

15.72

(14.81 to 16.75)

-0.35

(-0.39 to -0.30)

50,186

(36,235 to 65,544)

19.79

(14.41 to 25.57)

-0.24

(-0.30 to -0.16)

1,193,339

(1,134,407 to 1,261,299)

473.87

(449.62 to 501.06)

-0.39

(-0.43 to -0.35)

 Western Europe

77,225

(72,044 to 82,464)

9.41

(8.93 to 9.99)

-0.41

(-0.44 to -0.37)

116,117

(102,873 to 129,245)

24.45

(21.91 to 26.93)

-0.19

(-0.22 to -0.16)

1,832,992

(1,752,143 to 1,930,379)

260.88

(250.64 to 273.57)

-0.44

(-0.47 to -0.41)

 Western Sub-Saharan Africa

78,736

(61,695 to 99,765)

37.50

(30.28 to 46.47)

-0.29

(-0.45 to -0.11)

100,452

(80,812 to 121,906)

26.22

(19.92 to 33.23)

0.10

(0.04 to 0.17)

2,862,344

(2,196,425 to 3,688,871)

1052.18

(823.19 to 1337.56)

-0.30

(-0.45 to -0.11)