Table 3 Lymphocyte subpopulation and cytokine levels of Delta-infected patients at admission to the hospital

Lymphocyte subpopulations

Total T cells, per µl

1051.0 (712.0-1441.5)

686.0 (485.3-875.5)

947 (484–1320)

< 0.0001

0.715

0.299

Total T cells, %

70.76 (65.53–74.99)

68.94 (59.66–74.05)

78.61 (74.10-80.38)

0.335

0.727

0.832

CD4⁺ T cells, per µl

610.0 (428.5–830.0)

382.5 (290.5-511.8)

246 (56–540)

< 0.0001

0.0008

0.375

CD4⁺ T cells, %

42.96 (37.61–47.61)

39.19 (31.64–44.99)

21.04 (4.28–36.26)

0.266

0.145

0.453

CD8⁺ T cells, per µl

381.0 (250.5-474.5)

243.0 (134.0-335.5)

595 (340–973)

0.0027

0.0004

< 0.0001

CD8⁺ T cells, %

24.26 (21.13–29.54)

23.73 (19.10-31.35)

52.68 (42.66–60.48)

0.407

0.367

0.191

CD4/CD8 ratio

1.82 (1.41–2.15)

1.48 (1.12–2.20)

0.37 (0.07–0.94)

0.243

0.084

0.330

B cells, per µl

211.0 (138.5-295.5)

108.0 (74.0-165.75)

136 (98–153)

< 0.0001

< 0.0001

1.0

B cells, %

13.42 (11.04–16.17)

10.76 (8.05–14.87)

10.78 (7.57–16.16)

0.062

0.114

0.627

NK cells, per µl

168 (107-267.5)

140.0 (115.8-219.3)

108 (64–180)

0.231

0.074

0.311

NK cells, %

11.76 (8.04–16.96)

13.22 (11.11–23.27)

9.22 (7.08–11.34)

0.497

0.443

0.734

Cytokines

IL-2

9.75 (7.13–24.95)

10.45 (7.65–14.63)

2.5 (2.5–8.65)

0.424

0.193

0.430

IL-4

6.25 (5.00-11.18)

7.1 (6.3–10.6)

2.5 (2.5–6.43)

0.270

0.297

0.706

IL-6

44.75 (42.48–59.78)

49.40 (43.85–62.25)

49.3 (45.38-64)

0.482

0.683

1.0

IL-10

5.1 (3.9–7.8)

6.35 (4.90–9.45)

2.5 (2.5–3.78)

0.625

0.179

0.318

IL-12p70

0.95 (0.08–1.90)

1.2 (0.65–1.93)

2.5 (1.1–2.5)

0.302

0.624

0.918

IL-17 A

147.7 (147-148.5)

148.6 (147.5-151.6)

148.1 (147.3-148.5)

0.221

0.640

0.818

IFN-γ

46.4 (45.6–48.0)

47.20 (46.18–48.93)

102.4 (48-121.9)

0.745

0.485

0.354

TNF-a

2.45 (1.10–5.78)

2.25 (1.18–4.65)

2.5 (1.7–2.5)

0.998

0.252

0.281