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Table 2 Risk of osteoarthritis according to CRP and the joint effect of MetS and CRP

From: Metabolic syndrome increases osteoarthritis risk: findings from the UK Biobank prospective cohort study

 

No of cases/Person-years

Hazard Ratio (95% CI)

Model 1

Model 2

Model 3

CRP

  < 3.0 mg/L

290,494/3,455,944

Reference

Reference

Reference

  ≥ 3.0 mg/L

79,817/909,260

1.23(1.21,1.26)

1.21(1.18,1.23)

1.20(1.16,1.23)

CRP-Mets joint

 No MetS/CRP < 3.0 mg/L

257,812/2,827,142

Reference

Reference

Reference

 No MetS/CRP ≥ 3.0 mg/L

66,918/523,415

1.25(1.22,1.29)

1.22(1.19,1.26)

1.22(1.18,1.25)

 MetS/CRP < 3.0 mg/dL

32,682/628,801

1.19(1.15,1.23)

1.16(1.13,1.21)

1.15(1.11,1.19)

 MetS/CRP ≥ 3.0 mg/dL

12,899/385,844

1.42(1.37,1.47)

1.37(1.32,1.42)

1.35(1.30,1.40)

  1. Abbreviations:MetS metabolic syndrome, CRP C-reactive protein