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Table 1 Baseline characteristics of participants stratified by MetS in the UK biobank cohort

From: Metabolic syndrome increases osteoarthritis risk: findings from the UK Biobank prospective cohort study

Characteristics

MetS

Overall

N = 370,311

No (N = 281,018)

Yes (N = 89,293)

Mean (SD) age, years

55.97 (8.18)

57.96 (7.78)

56.45 (8.13)

Gender

 Male, N (%)

129,116(45.9)

45,495(51.0)

174,611(47.2)

 Female, N (%)

151,902(54.1)

43,798(49.0)

195,700(52.8)

Ethnic, (white) N (%)

265,662 (94.5)

84,292 (94.4)

349,954 (94.5)

Age, years, N (%)

  < 55

133,964 (47.7)

33,162 (37.1)

167,126 (45.1)

 55–65

112,849 (40.2)

41,462 (46.4)

154,311 (41.7)

  > 65

34,205 (12.2)

14,669 (16.4)

48,874 (13.2)

Mean (SD) IMD

16.32 (13.39)

19.12 (14.99)

17.00 (13.84)

Mean (SD) HDL, mmol/L

1.52 (0.38)

1.23 (0.29)

1.45 (0.38)

Mean (SD) TG, mmol/L

1.52 (0.86)

2.39 (1.17)

1.73 (1.01)

Mean (SD) fasting glucose, mmol/L

4.97 (0.93)

5.74 (1.81)

5.11 (1.23)

Mean (SD) SBP, mmHg

137.33 (19.67)

145.98 (18.15)

139.42 (19.67)

Mean (SD) DBP, mmHg

80.98 (10.56)

86.28 (10.30)

82.26 (10.74)

Waist circumference (cm)

85.44 (10.76)

103.78 (10.55)

89.86 (13.28)

Mean (SD) BMI, kg/m2

25.60 (3.47)

32.16 (4.29)

27.18 (4.63)

Alcohol consumption, N (%)

 Daily or almost daily

60,798 (21.6)

15,557 (17.4)

76,355 (20.6)

 1–4 times a week

143,164 (50.9)

40,513 (45.4)

183,677 (49.6)

 1–3 times a month

29,825 (10.6)

11,316 (12.7)

41,141 (11.1)

 Special occasions only/Never

47,231 (16.8)

21,907 (24.5)

69,138 (18.7)

 Median (IQR) Physical activity, MET hours/week

31.54(46.48)

23.44(41.02)

29.55(45.55)

Smoking status(%)

 Current

29,504 (10.5)

9,865 (11.0)

39,369 (10.6)

 Previous

90,020 (32.0)

35,033 (39.2)

125,053 (33.8)

 Never

161,494 (57.5)

44,395 (49.7)

205,889 (55.6)

 NSAIDs, N(%)

41,634 (14.8)

14,238 (15.9)

55,872 (15.1)

 ASP, N(%)

30,024 (10.7)

20,584 (23.1)

50,608 (13.7)

 Fruit&vegetable, N (%)

106,362 (37.8)

31,390 (35.2)

137,752 (37.2)

 Vitamin, N(%)

42,615 (15.2)

12,120 (13.6)

54,735 (14.8)

 Mineral, N(%)

61,513 (21.9)

17,344 (19.4)

78,857 (21.3)

 Mean(SD) CRP, mg/L

2.09(3.94)

3.73(4.76)

2.49 (4.21)

MetS components

 Central obesity, N(%)

34,514 (12.28)

82,480 (92.37)

116,994 (31.59)

 Dyslipidaemia for HDL, N(%)

3,6368 (12.94)

40,276 (45.11)

76,644 (20.70)

 Dyslipidaemia for TG, N(%)

97,916 (34.84)

77,645 (86.96)

175,561 (47.41)

 Hyperglycemia, N(%)

33,734 (12.01)

34,212 (38.31)

67,946 (18.35)

 Hypertension, N(%)

184,781 (65.75)

82,905 (92.85)

267,686 (72.29)

  1. Abbreviations: MetS metabolic syndrome, IMD Index of Multiple Deprivation, HDL high-density lipoprotein, TG triglyceride, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, MET Metabolic equivalent of task, Fruit&vegetable Fruit&vegetable intake ≥ 5 portions per-day, CRP C-reactive protein