Table 1 Baseline characteristics of participants in this secondary analysis

Age (years, SD)

46.4 (10.8)

47.1 (12.7)

0.846^a

48.0 (9.1)

48.5 (8.6)

0.878^a

Height (cm, SD)

174.5 (5.6)

172.5 (5.1)

0.166^a

159.7 (4.9)

159.1 (4.7)

0.709^a

Body weight (kg, SD)

74.4 (10.2)

74.2 (9.8)

0.945^a

57.0 (12.2)

55.0 (9.4)

0.584^c

Genes involved in alcohol metabolism

ADH1B (number of participants, %)

0.002^b

0.933^b

*1/*1

4 (14.8)

1 (3.8)

4 (10.0)

2 (7.1)

*1/*2

5 (18.5)

6 (23.1)

11 (27.5)

9 (32.1)

*2/*2

18 (66.7)

19 (73.1)

25 (62.5)

17 (60.7)

ALDH2 (number of participants, %)

0.024^b

0.886^d

*1/*1

19 (70.4)

25 (96.2)

32 (80.0)

22 (78.6)

*1/*2

8 (29.6)

1 (3.8)

8 (20.0)

6 (21.4)

*2/*2

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

AUDIT (points, median, IQR)

12.0 (8.0)

12.5 (4.5)

0.808^c

8.0 (5)

8.0 (8.0)

0.364^c

Binge drinking

(times/month, median, IQR)

6.0 (14.0)

5.0 (22.8)

0.814^c

2.0 (10.0)

4.0 (10.0)

0.694^c

Number of HED episodes (times/4 weeks, median, IQR)

6.0 (19.0)

5.0 (13.8)

0.870^c

1.0 (3.0)

1.0 (4.0)

0.601^c

AQoLS (points, median, IQR)

2.0 (4.0)

3.0 (5.5)

0.566^c

1.0 (4.0)

3.0 (5.3)

0.138^c

Subjective view of health (number of participants, %)

0.389^b

0.319^b

Very healthy

5 (18.5)

6 (23.1)

10 (25.0)

11 (39.3)

Fairly healthy

22 (81.5)

18 (69.2)

28 (70.0)

17 (60.7)

Not so healthy

0 (0.0)

2 (7.7)

2 (5.0)

0 (0.0)

Not healthy

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)