United States (n = 15a ) | Germany (n = 12b) | Italy (n = 12) | China (n = 12) | Japan (n = 12) | Total (N = 63) | |
---|---|---|---|---|---|---|
Sex, n (%) | ||||||
Female | 8 (53) | 7 (58) | 8 (67) | 7 (58) | 9 (75) | 39 (62) |
Male | 7 (47) | 5 (42) | 4 (33) | 5 (42) | 3 (25) | 24 (38) |
Mean age, yearsc | 36 | 48.8 | 53.4 | 38 | 58.1 | 48.8 |
Median age (range), yearsc | 49.5 (36–58) | 52 (31–65) | 58.5 (29–71) | 38 (25–57) | 59.5 (44–70) | 50.0 (25–71) |
Ethnicity, n (%) | ||||||
Asian | 5 (36) | 1 (8) | 0 | 12 (100) | 12 (100) | 30 (48) |
Black/African American | 1 (7) | 0 | 0 | 0 | 0 | 1 (2) |
Caucasian/White | 6 (43) | 10 (83) | 12 (100) | 0 | 0 | 28 (44) |
Hispanic | 2 (14) | 0 | 0 | 0 | 0 | 2 (3) |
Other | 0 | 1 (8) | 0 | 0 | 0 | 1 (2) |
Living status, n (%) | ||||||
Living with partner/spouse | 4 (29) | 3 (25) | 2 (17) | 9 (75) | 4 (33) | 22 (35) |
Living with partner and children | 5 (36) | 1 (8) | 5 (42) | 0 | 5 (42) | 16 (25) |
Living with children | 1 (7) | 1 (8) | 2 (17) | 0 | 0 | 4 (6) |
Living with family | 1 (7) | 0 | 1 (8) | 1 (8) | 1 (8) | 4 (6) |
Living alone | 3 (21) | 7 (58) | 2 (17) | 1 (8) | 1 (8) | 14 (22) |
Living with parents | 0 | 0 | 0 | 1 (8) | 0 | 1 (2) |
Other | 0 | 0 | 0 | 0 | 1 (8) | 1 (2) |
Highest education level, n (%) | ||||||
Junior high school | 0 | 0 | 0 | 0 | 2 (17) | 2 (3) |
High school | 1 (7) | 0 | 1 (8) | 4 (33) | 1 (8) | 7 (11) |
Technical college | 0 | 0 | 0 | 0 | 4 (33) | 4 (6) |
Apprenticeship | 0 | 2 (17) | 0 | 0 | 0 | 2 (3) |
Vocational training | 0 | 5 (42) | 0 | 8 (67)d | 0 | 13 (21) |
College or associate’s degree | 6 (40) | 1 (8) | 7 (58) | 0 | 22 (35) | |
University | 0 | 4 (33) | 1 (8) | 5 (42) | 18 (29) | |
Bachelor’s degree | 2 (13) | 0 | 1 (8) | 0 | 11 (17) | |
Graduate or postgraduate degree | 6 (40) | 0 | 2 (17) | 0 | 0 | 8 (13) |
Employment status, n (%)e | ||||||
Employed full-time | 12 (80) | 5 (45) | 2 (17) | 9 (75) | 6 (50) | 34 (55) |
Employed part-time | 2 (13) | 3 (27) | 0 | 0 | 3 (25) | 8 (13) |
Unemployed | 1 (7) | 1 (9) | 2 (17) | 3 (25) | 1 (8) | 8 (13) |
Retired | 0 | 1 (9) | 3 (25) | 0 | 2 (17) | 6 (10) |
Other | 0 | 1 (9) | 4 (33) | 0 | 0 | 5 (8) |
Mean time since diagnosis, yearsf | 10.7 | 10.5 | 11.7 | 10.6 | 19.7 | 12.5 |
Genotype, n (%) | ||||||
Genotype A | 4 (27) | 10 (83) | 0 | 0 | 0 | 14 (22) |
Genotype B | 2 (13) | 0 | 0 | 0 | 1 (8) | 3 (5) |
Genotype C | 1 (7) | 1 (8) | 0 | 0 | 3 (25) | 5 (8) |
Genotype D | 1 (7) | 1 (8) | 1 (8) | 0 | 0 | 3 (5) |
Unknown/NR | 7 (47) | 0 | 11 (92) | 12 (100) | 8 (67) | 38 (60) |
Treatment naïve, n (%) | 2 (13) | 4 (33) | 3 (25) | 0 | 1 (8) | 10 (16) |
Current treatment, n (%) | ||||||
NRTI | 6 (40) | 8 (67) | 4 (33) | 8 (67) | 4 (33) | 30 (48) |
Tenofovir | 2 (13) | 6 (50) | NR | 2 (17) | NR | 10 (16) |
Entecavir | 4 (27) | 2 (17) | NR | 6 (50) | NR | 12 (19) |
Azathioprine | 0 | 0 | 2 (17) | 0 | 0 | 2 (3) |
Unknown | 0 | 0 | 0 | 0 | 2 (17) | 2 (3) |
Prednisone | 0 | 0 | 1 (8) | 0 | 0 | 1 (2) |
Ursodiol | 0 | 0 | 2 (17) | 0 | 0 | 2 (3) |
Furosemide | 0 | 0 | 1 (8) | 0 | 0 | 1 (2) |
Interferon | 2 (13) | 1 (8) | 0 | 3 (25) | 2 (17) | 8 (13) |
Lamivudine | 1 (7) | 0 | 2 (17) | 1 (8) | 1 (8) | 5 (8) |
Tenofovir alafenamide | 1 (7) | 0 | 0 | 0 | 0 | 1 (2) |
Adefovir dipivoxil | 0 | 0 | 0 | 2 (17) | 0 | 2 (3) |
Thymopolypeptides | 0 | 0 | 0 | 1 (8) | 0 | 1 (2) |
Traditional Chinese medicine | N/A | N/A | N/A | 6 (50) | 1 (8) | 7 (11) |
Unknown | 2 (13) | 0 | 0 | 1 (8) | 1 (8) | 4 (6) |
Not currently on treatment | 2 (13) | 0 | 0 | 0 | 5 (42) | 7 (11) |
Time since treatment initiation, n (%) | ||||||
3–24 months | 7 (47) | 6 (50) | 7 (58) | 5 (42) | 1 (8) | 26 (41) |
> 24 months | 3 (20) | 2 (17) | 2 (17) | 8 (67) | 5 (42) | 20 (32) |
Unknown | 1 (7) | 0 | 0 | 0 | 0 | 1 (2) |
Comorbidities, n (%) | ||||||
None | 8 (53) | 6 (50) | 5 (42) | 8 (67) | 7 (58) | 34 (54) |
Depression | 3 (20)g | 0 h | 0 h | 0 | 1 (8) | 4 (6) |
Anxiety | 2 (13) | 0 | 1 (8) | 0 | 0 | 3 (5) |
High blood pressure | 1 (7) | 4 (33) | 2 (17) | 0 | 1 (8) | 8 (13) |
Heart disease | 0 | 3 (25) | 1 (8) | 0 | 0 | 4 (6) |
Congestive heart failure | 0 | 2 (17) | 1 (8) | 0 | 0 | 3 (5) |
Diabetes | 0 | 2 (17) | 4 (33) | 0 | 2 (17) | 8 (13) |
Stroke | 0 | 0 | 1 (8) | 0 | 0 | 1 (2) |
Asthma/respiratory disease | 0 | 1 (8) | 4 (33) | 0 | 0 | 5 (8) |
COPD | 0 | 1 (8) | 3 (25) | 0 | 0 | 4 (6) |
Thyroid disease | 0 | 0 | 6 (50) | 1 (8) | 0 | 7 (11) |
Arthritis/osteoarthritis | 0 | 0 | 3 (25) | 0 | 1 (8) | 4 (6) |
Cancer | 0 | 0 | 1 (8) | 0 | 2 (17) | 3 (5) |
Other | 1 (7) | 2 (17) | 0 | 3 (25) | 2 (17) | 8 (13) |