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Table 1 Characteristics of included trials

From: Vitamin C reduces the severity of common colds: a meta-analysis

Trial [ref]

Country

Participants

Age

mean

(y)

Number of colds

Vitamin C dose

(g/day)

Duration of the trial

(months)

Ludvigsson (1977 L) [30]

Sweden

Schoolchildren

9

1279

1

3

Pitt (1979) [41]

USA

Marine recruits

19

1219

2

2

Anderson 1972 [28, 29]

Canada

Adults

29

1170

1 + 3

3

Anderson 1974#3 [26]

Canada

Adults

34

611

2

3

Anderson 1974#1 [26]

Canada

Adults

34

581

1 + 3

3

Anderson 1974#2 [26]

Canada

Adults

34

560

1

3

Ludvigsson (1977P) [30]

Sweden

Schoolchildren

10

236

1

3

Carr (1981T) [42]

Australia

Twin adults and adolescents together

25

164

1

3

Carr (1981 A) [42]

Australia

Twin adults and adolescents apart

25

128

1

3

Miller (1977) [43]

USA

Schoolchildren

12 1)

118

1

5

Constantini (2011 F) [36]

Israel

Adolescent female competitive swimmers

14

51

1

3

Ritzel (1961) [14, 15]

Switzerland

Schoolchildren in a skiing camp

12 1)

48

1

0.2

Constantini (2011 M) [36]

Israel

Adolescent male competitive swimmers

14

47

1

3

Himmelstein (1998) [35]

USA

Adults

44

26

1

3

Sabiston 1974 [44]

Marine recruits

25

20

1

0.2

  1. 1) Miller included 6–17-year-old children, but mean age was not published; 12 years is the middle of the range [43]. Ritzel’s trial included “school children in two skiing courses”, but age is not described; we assume age around 12 years [14]