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Table 4 Mediation effect of BMI on the association between diet soft drink consumption and MASLD

From: Association between diet soft drink consumption and metabolic dysfunction-associated steatotic liver disease: findings from the NHANES

Mediator

Exposure to mediator

Mediator to outcome

Direct effect

Mediated

(indirect effect)

Total effect (exposure to outcome)

Proportion mediated (%)

BMI

Estimate

1.558

0.673

0.015

0.085

0.100

84.7

SE/CI 95%

0.266

0.030

(-0.010, 0.040)

(0.056, 0.110)

(0.062, 0.140)

P value

< 0.001

< 0.001

0.230

< 0.001

< 0.001

< 0.001

  1. MASLD: metabolic dysfunction-associated steatotic liver disease; BMI: body mass index; Exposure: diet soft drink consumption; Outcome: MASLD; model adjusted for age, gender, race, education level, smoking, physical intensity, carbohydrate intake, dietary fiber intake, PUFA intake, hypertension, hyperlipidemia, and diabetes mellitus