Table 3 Crude and adjusted association of T2D with amino acid profile quartiles
Amino Acids | n case/control | Model I | Model II | Model III |
|---|---|---|---|---|
OR (95% CI) | ||||
Branched-chain | ||||
 Q1 | 24/119 | 1.00 | 1.00 | 1.00 |
 Q2 | 28/112 | 1.23 (0.67-2.26) | 1.55 (0.79-3.03) | 1.91 (0.92-3.97) |
 Q3 | 23/118 | 0.96 (0.51-1.80) | 1.15 (0.57-2.33) | 1.31 (0.58-2.94) |
 Q4 | 38/103 | 1.82 (1.02-3.25) | 1.90 (0.98-3.70) | 2.70 (1.16-6.31) |
Aromatic | ||||
 Q1 | 24/118 | 1.00 | 1.00 | 1.00 |
 Q2 | 27/114 | 1.16 (0.63-2.13) | 1.30 (0.66-2.55) | 1.59 (0.76-3.35) |
 Q3 | 26/115 | 1.11 (0.60-2.04) | 1.30 (0.65-2.59) | 1.47 (0.66-3.28) |
 Q4 | 36/105 | 1.68 (0.94-3.00) | 1.67 (0.85-3.25) | 2.36 (0.99-5.61) |
Alkaline | ||||
 Q1 | 24/118 | 1.00 | 1.00 | 1.00 |
 Q2 | 26/115 | 1.11 (0.60-2.04) | 1.39 (0.70-2.73) | 1.59 (0.76-3.32) |
 Q3 | 24/117 | 1.00 (0.54-1.87) | 1.16 (0.58-2.32) | 1.18 (0.52-2.66) |
 Q4 | 39/102 | 1.87 (1.05-3.33) | 1.92 (0.99-3.73) | 2.68 (1.16-6.21) |
Sulfuric | ||||
 Q1 | 23/119 | 1.00 | 1.00 | 1.00 |
 Q2 | 32/109 | 1.51 (0.83-2.75) | 1.71 (0.88-3.31) | 2.22 (1.08-4.56) |
 Q3 | 21/120 | 0.90 (0.47-1.72) | 1.07 (0.52-2.19) | 1.20 (0.53-2.74) |
 Q4 | 37/104 | 1.84 (1.02-3.29) | 1.95 (0.99-3.83) | 2.98 (1.27-6.96) |
Acidic | ||||
 Q1 | 26/116 | 1.00 | 1.00 | 1.00 |
 Q2 | 23/118 | 0.86 (0.46-1.61) | 0.97 (0.49-1.92) | 1.09 (0.51-2.31) |
 Q3 | 28/113 | 1.10 (0.61-2.00) | 1.30 (0.66-2.54) | 1.34 (0.61-2.94) |
 Q4 | 36/105 | 1.52 (0.86-2.70) | 1.43 (0.74-2.77) | 1.80 (0.74-4.35) |
Alcoholic | ||||
 Q1 | 24/118 | 1.00 | 1.00 | 1.00 |
 Q2 | 26/115 | 1.11 (0.60-2.04) | 1.25 (0.63-2.45) | 1.48 (0.70-3.11) |
 Q3 | 27/114 | 1.16 (0.63-2.13) | 1.37 (0.69-2.72) | 1.64 (0.74-3.64) |
 Q4 | 36/105 | 1.68 (0.94-3.00) | 1.71 (0.87-3.34) | 2.45 (1.02-5.90) |
Small amino acids | ||||
 Q1 | 26/116 | 1.00 | 1.00 | 1.00 |
 Q2 | 23/118 | 0.86 (0.46-1.61) | 1.00 (0.50-1.99) | 1.15 (0.54-2.45) |
 Q3 | 25/116 | 0.96 (0.52-1.76) | 1.04 (0.53-2.04) | 1.07 (0.48-2.39) |
 Q4 | 39/102 | 1.70 (0.97-2.99) | 1.67 (0.87-3.20) | 2.16 (0.94-4.97) |
Proline | ||||
 Q1 | 26/116 | 1.00 | 1.00 | 1.00 |
 Q2 | 26/115 | 1.00 (0.55-1.84) | 1.13 (0.58-2.21) | 1.22 (0.59-2.53) |
 Q3 | 29/112 | 1.15 (0.64-2.08) | 1.14 (0.58-2.22) | 1.26 (0.58-2.74) |
 Q4 | 32/109 | 1.30 (0.73-2.33) | 1.37 (0.69-2.71) | 1.67 (0.70-3.99) |
Essential | ||||
 Q1 | 24/118 | 1.00 | 1.00 | 1.00 |
 Q2 | 30/111 | 1.32 (0.73-2.41) | 1.66 (0.85-3.22) | 2.05 (0.99-4.24) |
 Q3 | 21/120 | 0.86 (0.45-1.62) | 0.99 (0.48-2.01) | 1.06 (0.46-2.42) |
 Q4 | 38/103 | 1.81 (1.02-3.22) | 1.90 (0.97-3.73) | 2.66 (1.13-6.25) |
Non-essential | ||||
 Q1 | 25/118 | 1.00 | 1.00 | 1.00 |
 Q2 | 25/115 | 1.02 (0.55-1.89) | 1.16 (0.59-2.27) | 1.36 (0.64-2.87) |
 Q3 | 28/113 | 1.16 (0.64-2.12) | 1.43 (0.73-2.82) | 1.58 (0.71-3.50) |
 Q4 | 35/106 | 1.55 (0.87-2.77) | 1.45 (0.74-2.82) | 1.89 (0.79-4.54) |