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Table 5 Subgroups analysis for the associations of ALB with the risk of MetS

From: The association of female reproductive factors with risk of metabolic syndrome in women from NHANES 1999–2018

 

≤ 24

25–29

30–34

35–39

 ≥ 40

P for trend

P for interaction

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

Age

      

0.020

 45

1.00

1.22 (0.99, 1.52)

1.22 (0.96, 1.55)

1.15 (0.84, 1.58)

1.24 (0.64, 2.42)

0.925

 

 ≥ 45

1.00

1.00 (0.86, 1.15)

1.01 (0.87, 1.17)

1.01 (0.86, 1.18)

1.00 (0.80, 1.25)

0.320

 

Race

      

< 0.001

 Mexican

1.00

1.14 (0.86, 1.51)

1.07 (0.80, 1.43)

1.11 (0.81, 1.52)

1.35 (0.90, 2.04)

0.526

 

 American

       

 Other

1.00

1.64 (1.10, 2.44)*

1.22 (0.80, 1.84)

1.77 (1.13, 2.76)*

0.81 (0.37, 1.79)

0.701

 

 Hispanic

       

 Non-Hispanic

1.00

0.97 (0.76, 1.25)

0.95 (0.73, 1.25)

1.04 (0.76, 1.42)

1.02 (0.62, 1.68)

0.885

 

 Black

       

 Non-Hispanic

1.00

1.10 (0.92, 1.32)

1.17 (0.97, 1.42)

1.05 (0.84, 1.32)

1.12 (0.79, 1.58)

0.106

 

 White

       

 Other Race

1.00

0.82 (0.49, 1.37)

1.14 (0.69, 1.87)

0.84 (0.48, 1.48)

0.67 (0.30, 1.47)

0.559

 

Menopause status

      

0.014

 No

1.00

1.22 (0.88, 1.71)

1.10 (0.77, 1.58)

1.23 (0.79, 1.90)

0.91 (0.45, 1.86)

0.576

 

 Yes

1.00

1.04 (0.92, 1.18)

1.03 (0.93, 1.22)

1.03 (0.88, 1.19)

1.05 (0.84, 1.31)

0.565

 

Hysterectomy

      

0.039

 No

1.00

1.15 (0.99, 1.33)

1.20 (1.03, 1.39)*

1.15 (0.97, 1.36)

1.08 (0.84, 1.37)

0.245

 

 Yes

1.00

1.00 (0.83, 1.22)

0.95 (0.76, 1.17)

0.99 (0.76, 1.29)

1.15 (0.76, 1.75)

0.721

 

Female hormone

      

0.025

 No

1.00

1.11 (0.97, 1.28)

1.05 (0.91, 1.21)

1.10 (0.93, 1.29)

1.04 (0.82, 1.31)

0.179

 

 Yes

1.00

1.03 (0.82, 1.31)

1.27 (0.99, 1.63)

1.02 (0.76, 1.36)

1.20 (0.75, 1.93)

0.430

 

Age at Menarche

      

0.012

 12

1.00

1.17 (0.92, 1.50)

1.14 (0.88, 1.49)

0.97 (0.71, 1.34)

1.09 (0.66, 1.80)

0.94

 

 12–13

1.00

0.99 (0.84, 1.16)

1.05 (0.88, 1.24)

0.95 (0.78, 1.16)

0.97 (0.72, 1.31)

0.341

 

 13

1.00

1.26 (0.99, 1.60)

1.21 (0.95, 1.55)

1.41 (1.08, 1.83)*

1.35 (0.93, 1.96)

0.762

 

Fertile lifespan

      

0.006

 28

1.00

1.06 (0.89, 1.26)

1.01 (0.83, 1.23)

1.04 (0.80, 1.35)

1.06 (0.61, 1.85)

0.778

 

 28–35

1.00

1.00 (0.85, 1.18)

1.07 (0.90, 1.27)

0.98 (0.81, 1.20)

1.01 (0.75, 1.36)

0.406

 

 35

1.00

1.26 (0.99, 1.60)

1.22 (0.96, 1.56)

1.43 (1.10, 1.86)*

1.38 (0.95, 2.00)

0.786

 
  1. Analyses was adjusted for age, race/ethnicity, education level, marriage status, family PIR, hypertension, smoking, and alcohol use, coronary heart disease, congestive heart-failure, heart attack, angina and stroke, age at menopause, body mass index, waist circumference, systolic blood pressure, diastolic blood pressure, mean energy intake, hemoglobin, fast glucose, glycosylated hemoglobin, menopausal status, age at menarche, oral contraceptives, use of female hormones, previous hysterectomy, bilateral ovariectomy, blood urea nitrogen, uric acid, serum creatinine, estimated glomerular filtration rate, total cholesterol, triglyceride, high-density lipoprotein-cholesterol, number of live births and pregnancies, pregnancy loss and fertile lifespan
  2. All P-values were calculated using ≤ 24 as the reference
  3. Abbreviations: ALB Age at last birth, MetS Metabolic syndrome, OR Odds ratio, CI Confidence interval
  4. *P < 0.05