Skip to main content

Table 4 Subgroups analysis for the associations of AFB with the risk of MetS

From: The association of female reproductive factors with risk of metabolic syndrome in women from NHANES 1999–2018

 

 < 18

18–20

21–23

24–26

27–29

30–32

33–35

 ≥ 36

P for trend

P for interaction

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

Age

         

0.006

 45

1.00

1.02 (0.81, 1.28)

0.99 (0.76, 1.28)

0.83 (0.60, 1.14)

1.10 (0.77, 1.57)

1.09 (0.68, 1.76)

2.01 (1.11, 3.65)*

0.46 (0.14, 1.48)

0.641

 

 ≥ 45

1.00

1.10 (0.94, 1.29)

1.03 (0.87, 1.21)

1.03 (0.86, 1.24)

1.07 (0.86, 1.24)

1.08 (0.82, 1.43)

0.76 (0.53, 1.11)

0.87 (0.55, 1.40)

0.373

 

Race

         

< 0.001

 Mexican

1.00

1.16 (0.90, 1.50)

1.32 (1.00, 1.74)*

1.25 (0.90, 1.74)

1.22 (0.81, 1.83)

0.98 (0.53, 1.78)

1.00 (0.44, 2.27)

1.36 (0.51, 3.65)

0.391

 

 American

          

 Other

1.00

1.08 (0.72, 1.62)

1.09 (0.70, 1.70)

1.16 (0.70, 1.93)

0.99 (0.52, 1.90)

1.66 (0.75, 3.66)

1.06 (0.39, 2.91)

1.42 (0.47, 4.33)

0.422

 

 Hispanic

          

 Non-Hispanic

1.00

0.88 (0.68, 1.12)

0.83 (0.62, 1.10)

0.72 (0.49, 1.04)

1.19 (0.75, 1.89)

1.32 (0.72, 2.44)

1.17 (0.54, 2.56)

0.78 (0.23, 2.62)

0.887

 

 Black

          

 Non-Hispanic

1.00

1.05 (0.83, 1.34)

0.99 (0.77, 1.27)

0.98 (0.75, 1.29)

1.01 (0.75, 1.29)

0.93 (0.64, 1.37)

0.92 (0.56, 1.50)

0.69 (0.35, 1.39)

0.315

 

 White

          

 Other race

1.00

2.04 (1.08, 3.84)*

1.02 (0.53, 1.96)

0.91 (0.47, 1.78)

1.54 (0.77, 3.10)

1.69 (0.78, 3.68)

0.87 (0.30, 2.51)

0.30 (0.05, 1.82)

0.576

 

Menopause status

         

0.001

 No

1.00

0.88 (0.63, 1.24)

0.83 (0.57, 1.21)

0.69 (0.45, 1.07)

0.98 (0.61, 1.57)

0.82 (0.44, 1.53)

1.66 (0.80, 3.46)

0.41 (0.13, 1.24)

0.703

 

 Yes

1.00

1.11 (0.96, 1.28)

1.05 (0.90, 1.22)

1.04 (0.87, 1.23)

1.11 (0.91, 1.36)

1.15 (0.89, 1.48)

0.84 (0.59, 1.19)

0.90 (0.56, 1.45)

0.766

 

Hysterectomy

         

0.001

 No

1.00

1.00 (0.85, 1.17)

1.04 (0.87, 1.23)

0.87 (0.72, 1.05)

1.03 (0.83, 1.28)

1.10 (0.84, 1.44)

0.98 (0.68, 1.41)

0.79 (0.49, 1.28)

0.687

 

 Yes

1.00

1.25 (1.00, 1.56)*

1.01 (0.80, 1.29)

1.31 (0.99, 1.73)

1.30 (0.90, 1.86)

1.07 (0.63, 1.83)

0.90 (0.45, 1.80)

0.79 (0.27, 2.29)

0.753

 

Female hormone

         

0.005

 No

1.00

1.10 (0.95, 1.27)

1.03 (0.88, 1.20)

0.91 (0.76, 1.10)

0.99 (0.81, 1.23)

1.04 (0.79, 1.36)

1.05 (0.73, 1.50)

0.84 (0.52, 1.34)

0.313

 

 Yes

1.00

1.02 (0.77, 1.35)

1.05 (0.78, 1.42)

1.28 (0.92, 1.78)

1.51 (0.92, 1.78)

1.29 (0.78, 2.14)

0.71 (0.34, 1.45)

0.59 (0.21, 1.64)

0.243

 

Age at menarche

         

0.151

 12

1.00

1.09 (0.83, 1.42)

1.02 (0.76, 1.37)

1.10 (0.78, 1.55)

1.09 (0.72, 1.65)

1.37 (0.79, 2.35)

0.75 (0.37, 1.54)

0.75 (0.28, 2.03)

0.979

 

 12–13

1.00

1.15 (0.96, 1.38)

1.04 (0.86, 1.27)

0.99 (0.79, 1.23)

1.08 (0.84, 1.41)

0.98 (0.70, 1.37)

1.02 (0.64, 1.61)

0.74 (0.39, 1.42)

0.371

 

 13

1.00

0.98 (0.75, 1.27)

1.00 (0.76,1.32)

0.97 (0.71, 1.32)

1.10 (0.78, 1.56)

1.17 (0.75, 1.81)

1.04 (0.58, 1.86)

0.93 (0.45, 1.90)

0.562

 

Fertile lifespan

         

0.001

 28

1.00

1.07 (0.88, 1.29)

0.99 (0.79, 1.22)

1.04 (0.80, 1.35)

1.12 (0.81, 1.54)

1.23 (0.79, 1.90)

1.06 (0.55, 2.04)

0.64 (0.21, 1.90)

0.725

 

 28–35

1.00

1.16 (0.97, 1.39)

1.05 (0.87, 1.28)

1.01 (0.81, 1.26)

1.11 (0.86, 1.44)

1.00 (0.72, 1.41)

1.05 (0.67, 1.66)

0.76 (0.40, 1.47)

0.529

 

 35

1.00

0.98 (0.75, 1.28)

1.00 (0.76, 1.33)

0.98 (0.72, 1.34)

1.11 (0.78, 1.57)

1.18 (0.76, 1.84)

1.06 (0.60, 1.89)

0.95 (0.46, 1.95)

0.491

 
  1. Analyses was adjusted for age, race/ethnicity, education level, marriage status, family PIR, hypertension, smoking, and alcohol use, coronary heart disease, congestive heart-failure, heart attack, angina and stroke, age at menopause, body mass index, waist circumference, systolic blood pressure, diastolic blood pressure, mean energy intake, hemoglobin, fast glucose, glycosylated hemoglobin, menopausal status, age at menarche, oral contraceptives, use of female hormones, previous hysterectomy, bilateral ovariectomy, blood urea nitrogen, uric acid, serum creatinine, estimated glomerular filtration rate, total cholesterol, triglyceride, high-density lipoprotein-cholesterol, number of live births and pregnancies, pregnancy loss and fertile lifespan
  2. All P-values were calculated using < 18 as the reference
  3. Abbreviations: AFB Age at first birth, MetS Metabolic syndrome, OR Odds ratio, CI Confidence interval
  4. *P < 0.05
Back to article page

BMC Public Health

ISSN: 1471-2458

Contact us