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Table 3 Associations of number of pregnancies, and number of live births with the risk of MetS

From: The association of female reproductive factors with risk of metabolic syndrome in women from NHANES 1999–2018

 

Model 1

Model 2

Model 3

OR (95%CI)

P for trend

OR (95%CI)

P for trend

OR (95%CI)

P for trend

Number of pregnancies

 

< 0.001

 

0.032

 

0.145

 ≤ 2

1.00

 

1.00

 

1.00

 

 3

1.01 (0.91, 1.09)

 

1.01 (0.89, 1.09)

 

1.01 (0.86, 1.08)

 

 4

1.12 (1.02, 1.24)*

 

1.08 (0.97, 1.21)

 

1.04 (0.92, 1.17)

 

 ≥ 5

1.22 (1.12, 1.34)***

 

1.10 (0.99, 1.22)

 

1.08 (0.96, 1.22)

 

Number of live births

 

< 0.001

 

0.002

 

0.021

 ≤ 2

1.00

 

1.00

 

1.00

 

 3

1.08 (0.99, 1.17)

 

1.05 (0.95, 1.15)

 

1.04 (0.94, 1.15)

 

 4

1.21 (1.10, 1.34)***

 

1.09 (0.97, 1.22)

 

1.05 (0.93, 1.19)

 

 ≥ 5

1.40 (1.26, 1.56)***

 

1.21 (1.07, 1.37)**

 

1.18 (1.04, 1.35)**

 
  1. Model 1: age and race/ethnicity
  2. Model 2: model 1 variables plus education level, marriage status, family PIR, hypertension, smoking, and alcohol use
  3. Model 3 was adjusted for model 2 variables plus coronary heart disease, congestive heart-failure, heart attack, angina and stroke, age at menopause, body mass index, waist circumference, systolic blood pressure, diastolic blood pressure, mean energy intake, hemoglobin, fast glucose, glycosylated hemoglobin, menopausal status, age at menarche, oral contraceptives, use of female hormones, previous hysterectomy, bilateral ovariectomy, blood urea nitrogen, uric acid, serum creatinine, estimated glomerular filtration rate, total cholesterol, triglyceride, high-density lipoprotein-cholesterol, number of live births and pregnancies, pregnancy loss and fertile lifespan
  4. Abbreviations: MetS Metabolic syndrome, OR Odds ratio, CI Confidence interval
  5. *P < 0.05, **P < 0.01, ***P < 0.001