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Table 1 Studies included in the meta-analysis investigating for the relationship between PM2.5 and COPD hospitalizations

From: Relationship between fine particulate matter (PM2.5) concentration and risk of hospitalization due to chronic obstructive pulmonary disease: a systematic review and meta-analysis

Author/year

Study location

Study design

Total period measured/month

Pollution exposure

Lag days

Ages

Confounders

Belleudi, 2010 [25]

Rome/Italy

TS

2001–2005/57

PM2.5, PM10, Particle number concentration

0,1,2,3,4,5,6,01,02,05,06

35–64

65–74

 ≥ 75

WD

Qiu, 2012 [26]

China/Hong Kong

TS

200–2005/72

PM10 PM2.5, PMc NO2, SO2, O3

0,1,2,3,4,5,01,02,03

All

TT,T,H, I,OAP(NO2,SO2, O3

Kloog, 2014 [27]

United States of America

CC

2000–2006/84

PM2.5

01

 ≥ 65

T

To, 2015 [28]

Canada/Ontario

TS

2003–2010/96

NO2

O3

PM2.5

0

All

A,G,WD,T,SE,Y,SS,RR

Lopez-VillarrubiaL/P, 2016 [29]

L/P de Gran Canaria

TS

2001–2005/60

PM2.5,PM10-2.5, O3, NO2, SO2, CO

01

All

TT,WD,H,UE,T,RH,BP,I

Lopez-VillarrubiaS/C, 2016

S/C de Tenerife Canaria

TS

2001–2005/60

PM2.5,PM10-2.5, O3, NO2, SO2, CO

01

All

TT,WD,H,UE,T,RH,BP,I

Chang, 2017 [30]

Taiwan/Taipei

TS

2015–2012/49

PM2.5, NO2, SO2

0,1,2,3,4,5,6,7,8,9,10

All

 < 75

 > 75

T

Tian, 2018 [31]

 

TS

2010–2012/30

PM2.5

0,1,2,3,01,02,03

All

 < 65

 > 65

H,WD,RH,T

Johnstonb, 2019 [32]

Australian/Tasmania, Victoria, New South Wales

CC

2009–2014/72

PM2.5

0,1,2

All

W.M,LT

JohnstonbTas, 2019

Australian/Tasmania

CC

2009–2014/72

PM2.5

0,1,2

All

W.M,LT

JohnstonbVic, 2019

Australian/Victoria

CC

2009–2014/72

PM2.5

0,1,2

All

W.M,LT

JohnstonbNew, 2019

Australian/New South Wales

CC

2009–2014/72

PM2.5

0,1,2

All

W.M,LT

Hopke, 2019 [33]

United States of America/New York

CC

2005–2016/144

PM2.5

0,01,02,03,04,05,06

 ≥ 18

LT,M,UMC,Se

Bao, 2020 [34]

Lanzhou/ China

TS

48

PM2.5, PMC,

1,2,3,4,5,6,7,01,02,03,04,05,06,07

All

 < 65

 > 65

TT,WD,RH,T,H

Raji, 2020 [35]

Iran/Ahvaz

TS

120

O3, NO, NO2, SO2, CO, PM10, PM2.5

0,1,2,3,4,5,6,7

All

Se,T&RH, WD

Priyankara, 2021 [36]

Sri Lanka/Kandy

TS

2019/12

PM2.5, PM10

0, 1, 2, 3, 4, 5

All

WD, H

Capraz, 2021 [37]

Turkey/Istanbul

TS

2013–2017/59

PM10, PM2.5, NO2

0,1,2,3,4,5,6,7,8,9

All

T, RH

Jin, 2022 [38]

China/Guangzhou

CC

2014–2015/24

PM2.5

0,1,2,3,4,5,6,01,02,03,04,05,06

All

T, RH, H

Haung, 2021 [39]

Taiwan/Kaohsiung

CC

2007–2010/48

PM10, PM2.5, Nitrate, Sulfate, Organic carbon, Elemental carbon

0,1,2,3

All

 < 65

 > 65

T.RH

  1. Study Design: TS Time-Series, CC Case Crossover, Confounders: G Gender, A Age, Se Seasons, S Sex, OAP Other Air Pollution, TT Time Trend, W(T&H) Weather(Temperature,& Humidity), WD Weekdays, H Holidays, S-RI Self-Reported Influenza, RH Relative Humidity, DM Daily Meteorology, AA-SP Annual Age-Specific Population, ESS Education Smoking Status, Y Year, BMI Body Mass Index, DS Drinking Status, PA Physical Activity, DM Diabetes Mellitus, SS Socioeconomic Status, RR Region of Residence, LV Lifestyle Variables, (S,N,A,C,AB) (Sociodemographics, Neighbourhood, Anthropometrics, Comorbidities, Anhaematological Biomarkers), (H,H) (Hypertension, Hyperlipidemia), MF Meteorological Factor, LT Long Trend, M Monthly, UMC Underlying Medical Condition