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Table 1 Baseline characteristics of the training set and validation sets

From: Incomplete immune reconstitution and its predictors in people living with HIV in Wuhan, China

Variables

Derivation set

Internal validation set

External validation set

Age at ART initiation (years)

33 (25,49)

32 (25,48)

41 (28,51)

Sex(%)

 Male

2429(90.7)

1005(91.0)

716(81.5)

 Female

249(9.3)

100(9.0)

162(18.5)

Marital status(%)

 Married

786(29.4)

312(28.2)

367(41.8)

 Unmarried

1892(70.6)

793(71.8)

511(58.2)

Route of HIV exposure(%)

 MSM

1785(66.7)

764(69.1)

522(59.5)

 Heterosexual transmission

851(31.8)

334(30.2)

345(39.3)

 Injection drug use

18(0.7)

3(0.3)

4(0.5)

 Blood transfusion

3(0.1)

0(0)

3(0.3)

 Others

21(0.8)

4(0.4)

4(0.5)

Coinfection(%)

 HBsAg + 

234(8.7)

105(9.5)

61(6.9)

 Anti HCV + 

54(2.0)

27(2.4)

9(1.0)

 Herpes Zoster

108(4.0)

45(4.1)

30(3.4)

 PCP

72(2.7)

27(2.4)

17(1.9)

 Pulmonary infection

138(5.2)

62(5.6)

10(1.1)

 tumor

12(0.4)

3(0.3)

4(0.5)

WHO stage(%)

 I

574(21.4)

222(20.1)

504(57.4)

 II

1306(48.8)

559(50.6)

151(17.2)

 III

616(23.0)

245(22.2)

167(19.0)

 IV

182(6.8)

79(7.1)

56(6.4)

ART initiation regimen(%)

 AZT + 3TC + NVP/EFV

986(36.8)

375(33.9)

0.093

 D4T + 3TC + NVP/EFV

25(0.9)

10(0.9)

0.934

 TDF + 3TC + NVP/EFV

1570(58.6)

674(61.0)

0.177

 TDF + 3TC + LPV/r

18(0.7)

10(0.9)

0.447

 Other

79(2.9)

36(3.3)

0.616

 ART delay

1.4(0.9,2.6)

1.4(0.9,2.7)

1.4(0.6,6.6)

 BMI, kg/m

21.5(19.6,23.4)

21.3(19.6,23.4)

21.0(19.1,22.9)

  1. Abbreviations: MSM men who have sex with men, PCP pneumocystis carinii pneumonia, BMI body mass index, AZT zidovudine, 3TC lamivudine, NVP nevirapine, EFV efavirenz, D4T stavudine, TDF tenofovir disoproxil, LPV/r lopinavir/ritonavir