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Table 5 Studies regarding exposure to non-specific pesticides and hypothyroidism

From: Exposure to pesticides and the risk of hypothyroidism: a systematic review and meta-analysis

Authors (year)

Study site/Study design

Population

Sample size

Type of hypothyroidism

Outcome assessment

Source of exposure

Exposure assessment

Findings

OR/PR/IRR (95%CI)

Confounding variables

Kartini et al. (2018) [24]

Indonesia/ Cross-sectional study

Elementary school children (9–12 yrs.)

100

Subclinical hypothyroidism

Laboratory

Env

Interview

PR = 2.2(0.8,6.0)

-

Huang et al. (2017) [25]

Taiwan/Cohort study

Nationwide population

41,488

-Pesticide poisoning (10,372)

-No pesticide poisoning (31,116)

Any hypothyroidism

Physician diagnosis

Env

Interview

IRR = 1.40(1.07,1.83)a

-

Risal et al. (2019) [26]

Nepal/Retrospective cross-sectional study

Patients

288

-Hypothyroidism (116)

-No disease (172)

Any hypothyroidism

Laboratory

Env

Interview

OR = 2.18 (1.31, 3.63)a

-

  1. asignificant association; 95%CI 95% confidence interval, Env. Environmental exposure, HR Hazard ratio, IRR Incidence rate ratio, Occ. Occupational exposure, OR Odds ratio, PR Prevalence ratio