From: Exposure to pesticides and the risk of hypothyroidism: a systematic review and meta-analysis
Authors (year) | Study site/Study design | Population | Sample size | Type of hypothyroidism | Outcome assessment | Source of exposure | Exposure assessment | Findings OR/PR/IRR (95%CI) | Confounding variables |
---|---|---|---|---|---|---|---|---|---|
Kartini et al. (2018) [24] | Indonesia/ Cross-sectional study | Elementary school children (9–12 yrs.) | 100 | Subclinical hypothyroidism | Laboratory | Env | Interview | PR = 2.2(0.8,6.0) | - |
Huang et al. (2017) [25] | Taiwan/Cohort study | Nationwide population | 41,488 -Pesticide poisoning (10,372) -No pesticide poisoning (31,116) | Any hypothyroidism | Physician diagnosis | Env | Interview | IRR = 1.40(1.07,1.83)a | - |
Risal et al. (2019) [26] | Nepal/Retrospective cross-sectional study | Patients | 288 -Hypothyroidism (116) -No disease (172) | Any hypothyroidism | Laboratory | Env | Interview | OR = 2.18 (1.31, 3.63)a | - |