Table 3 Correlation coefficients between serum 25(OH)D levels and lipid profiles for included studies
No | Study | Population | n | correlation coefficient | Triglycerides | Total cholesterol | LDL | HDL | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
r | p value | r | p value | r | p value | r | p value | |||||
1 | Yildizhan 2009 [28] | obese and women with PCOS | 57 | Pearson’s correlation | -0.990 | 0.01 | -0.207 | NA | NA | NA | NA | NA |
2 | Bellia 2013Â [30] | severe obese subjects | 147 | a multivariate regression analysis (95% CI) | 0.0023 (-0010 to 0.0099) | 0.543 | -0.0013 (-0.0044 to 0.0014) | 0.473 | NA | NA | 0.0005 (-0.001 to 0.0015) | 0.642 |
3 | Boonchaya-anant 2014 [32] | Extremely Obese Individuals | 191 | Pearson’s correlation | -0.004 | 0.959 | 0.043 | 0.579 | 0.036 | 0.644 | 0.085 | 0.271 |
4 | Kozakowski 2014 [34] | women with polycystic ovary syndrome presenting abdominal and gynoidal type of obesity | 26 | Pearson’s correlation | abdominal: -0.97; gynoidal:-0.19 | abdominal: p < 0.01; gynoidal:p > 0.05 | abdominal: -0.4; gynoidal:-0.21 | p > 0.05 | abdominal: -0.42; gynoidal:-0.42 | p > 0.05 | abdominal: 0.65; gynoidal:0.33 | p > 0.05 |
5 | Amena Sadiya 2014 [33] | persons with obesity and type 2 Diabetes | 309 | Pearson’s correlation | -0.15 | 0.01 | -0.16 | p < 0.01 | -0.16 | p < 0.01 | 0.12 | p = 0.03 |
6 | Lu 2015 [37] | Chinese Postmenopausal Women with visceral obesity | 226 | partial correlation analysis | -0.127 | 0.007 | -0.082 | 0.082 | 0.02 | 0.675 | 0.02 | 0.675 |
7 | Mousa 2017 [39] | overweight/obese but otherwise healthy cohort | 111 | Pearson’s correlation | -0.07 | 0.5 | -0.09 | 0.3 | -0.13 | 0.2 | 0.05 | 0.6 |
8 | Ong 2018 [41] | Overweight and Obese Singaporeans Seeking Weight Management Including Bariatric Surgery | 111 | Pearson’s correlation | -0.14 | p > 0.05 | 0.06 | p > 0.05 | 0.05 | p > 0.05 | 0.177 | p > 0.05 |
9 | Curvello-Silva 2020 [42] | obese patients | 299 | Pearson’s correlation | -0.022 | 0.778 | -0.157 | 0.047 | -0.164 | 0.038 | -0.023 | 0.769 |
10 | Lara A da C. Dominoni 2022 [21] | adults with obesity | 52 | A regression coefficient (ß, 95% CI) | –0.794 CI:–3.19 to 1.60 | 0.508 | –0.477 CI: –1.92 to 0.97 | 0.511 | –0.251 CI:–1.53 to 1.03 | 0.696 | –0.144 CI:–0.76 to 0.48 | 0.644 |
11 | Salah Gariballa 2022 [20] | obese subject | 277 | Regression coefficient (95% CI) | 0.001 (-0.011 to 0.014) | 0.864 | NA | NA | -0.006 (-0.015 to 0.004) | 0.241 | 0.001 (-0.003 to 0.005) | 0.564 |
12 | Tong Gong 2022 [44] | overweight/obese patients with type 2 diabetes | 446 | Pearson’s correlation | -0.322 | p < 0.001 | -0.129 | 0.029 | 0.01 | 0.871 | 0.165 | 0.005 |