Table 2 MR estimates of associations between 5 types of exposure and OA risk

TC

32

MR Egger

OA

1.352(0.951,1.923)

0.103

WME

1 (0.780,1.283)

1

IVW

1.207(1.018,1.431)

0.031

Simple mode

1.109(0.701,1.757)

0.661

Weighted mode

1.098(0.797,1.511)

0.571

TG

39

MR Egger

0.855(0.644,1.134)

0.284

WME

0.917(0.724,1.161)

0.471

IVW

1.003(0.835,1.205)

0.97

Simple mode

1.855(1.107,3.109)

0.024

Weighted mode

0.831(0.659,1.049)

0.127

HDL

170

MR Egger

0.935 (0.731,1.197)

0.596

WME

1.128 (0.903,1.409)

0.29

IVW

1.074(0.922,1.252)

0.357

Simple mode

1.194(0.702,2.030)

0.515

Weighted mode

1.106(0.909,1.346)

0.316

LDL

60

MR Egger

1.151(0.700,1.891)

0.582

WME

1.583(1.088,2.303)

0.016

IVW

1.363(1.043,1.781)

0.023

Simple mode

1.521(0.776,2.980)

0.227

Weighted mode

1.521(1.062,2.178)

0.026

alcohol intake frequency

91

MR Egger

1.003(0.641,1.571)

0.989

WME

1.477(1.059,2.061)

0.022

IVW

1.326(1.047,1.678)

0.019

Simple mode

1.359(0.656,2.815)

0.412

Weighted mode

1.641(1.060,2.541)

0.029