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Table 3 Dimensions of RE-AIM in implementation research adapted for pay-it-forward (for MSM-led clinic sites)

From: Pay-it-forward gonorrhea and chlamydia testing among men who have sex with men and male STD patients in China: the PIONEER pragmatic, cluster randomized controlled trial protocol

Dimensions

Level

Operational definitions

Measurement method

Reach

Individual

• The proportion of MSM who enter the clinic who are screened for eligibility

• Percent of MSMs who visit the clinic compared to the MSM in the catchment area

• Administrative data will be collected on the demographics, socioeconomics, and geographic location (zip code or equivalent level) of those enrolled in pay-it-forward to test if there are differences in the characteristics of those who get tested and those who do not

• The population of MSMs will be collected from public data to assess the potential reach of the pay-it-forward intervention within the overall MSM population in the area

Effectiveness

Individual

• How effective are the two implementation strategies in promoting gonorrhea and chlamydia test uptake?

• Does pay-it-forward influence secondary outcomes (chlamydia testing, treatment, and prevention outcomes)?

• The primary outcome is gonorrhea and chlamydia test uptake from the RCT, which will be measured using administrative data from participating clinics

Adoption

Individual

• Do the participants find pay-it-forward acceptable and appropriate?

• Is there a relationship between acceptability and appropriateness and testing outcomes?

• What are the demographic, socio-economic, and geographic differences between those who found pay-it-forward acceptable and appropriate and those who did not?

• Quantitative data will be collected using an adapted version of the Acceptability of Intervention Measure (AIM) and the

• Intervention Appropriateness Measure (IAM). Qualitative data will be collected from interviews to gain additional insights into the results from these instruments

Organizational

• How do feelings of social reciprocity contribute to test adoption and donation behaviors?

• The R = MC2 instrument will be adapted for use in clinics

Implementation

Organizational

• What is the extent to which local staff implements the pay-it-forward according to the SOP, and to what extent are legitimate adaptations needed?

• Fidelity checklists (as specified by Carroll et al.) will be used to measure adherence to protocol related to content and dose

• Interviews with clinic staff will be used to determine reasons for deviation from protocol and to track and document legitimate adaptation

Maintenancea

Individual

• What is the average donation per participant in each arm?

• Is there a relationship between testing and donations?

• What are the facilitators and barriers to donation?

• What are the demographic, socio-economic, and geographic differences between men who tested after receiving the gift relative to those who were not?

• The tracking of donations stratified by testing status, socioeconomics, and demographics. Interviews with participants will examine the individual-level context of donating

Organizational

• What is the average donation per clinic in each arm?

• Is organizational readiness associated with higher donation rates?

• What are resource commitments from the public health sector, MSM organizations, and others to sustain pay-it-forward?

• Administrative data will be used to track donations at the clinic level

• Interviews with organizers who can continue the program after the 12-month RCT phase will examine facilitators and barriers to maintaining the intervention

  1. aMaintenance data will be collected for an additional 12 months (following the RCT) at selected clinics