From: Patterns of global burden of 13 diseases attributable to lead exposure, 1990–2019
Cause of DALYs | 1990 | 2019 | 1990–2019 | |||||||
---|---|---|---|---|---|---|---|---|---|---|
DALYs No.×105 (95% UI) | ASDR per 100 000 (95%UI) | Age-standardized PAF, % No. (95%UI) | DALYs No.×105 (95% UI) | ASDR per 100 000 (95%UI) | Age-standardized PAF, % No. (95%UI) | AAPC of ASDR (95%CI) | AAPC of age-standardized PAF (95%CI) | |||
All causes | ||||||||||
Both | 160.25 (103.21, 221.68) | 378.01 (240.55, 524.18) | 0.76 (0.48, 1.05) | 216.76 (138.13, 302.98) | 267.52 (170.57, 373.44) | 0.82 (0.53, 1.14) | -1.19 (-1.24, -1.14) | 0.28 (0.23, 0.33) | ||
Female | 58.31 (34.51, 84.98) | 260.52 (150.50, 383.12) | 0.56 (0.33, 0.82) | 80.43 (48.18, 117.28) | 188.85 (113.07, 274.64) | 0.62 (0.38, 0.90) | -1.12 (-1.19, -1.05) | 0.36 (0.29, 0.44) | ||
Male | 101.94 (68.25, 136.87) | 512.87 (339.34, 692.87) | 0.95 (0.63, 1.28) | 136.34 (88.81, 188.24) | 357.56 (233.38, 493.30) | 1.00 (0.67, 1.37) | -1.24 (-1.30, -1.18) | 0.20 (0.15, 0.26) | ||
Disease type | ||||||||||
Cardiovascular diseases | 128.85 (77.34, 186.47) | 318.54 (190.85, 461.21) | 4.50 (2.70, 6.45) | 177.35 (104.88, 256.6) | 216.80 (128.35, 314.82) | 4.46 (2.67, 6.35) | -1.32 (-1.39, -1.25) | -0.04 (-0.16, 0.08) | ||
Rheumatic heart disease | 3.20 (1.69, 5.44) | 7.18 (3.87, 12.16) | 2.53 (1.40, 4.25) | 2.14 (1.07, 3.73) | 2.58 (1.28, 4.55) | 1.95 (1.00, 3.42) | -3.46 (-3.58, -3.34) | -0.91 (-1.02, -0.80) | ||
Ischemic heart disease | 54.09 (31.78, 79.51) | 134.35 (78.06, 199.09) | 4.27 (2.50, 6.29) | 83.69 (48.96, 124.49) | 102.26 (59.74, 152.87) | 4.56 (2.72, 6.68) | -0.94 (-1.01, -0.88) | 0.22 (0.04, 0.40) | ||
Stroke | 54.37 (32.53, 79.52) | 133.36 (80.09, 195.09) | 4.88 (2.94, 7.03) | 67.39 (39.12, 98.16) | 81.97 (47.86, 119.11) | 4.64 (2.73, 6.69) | -1.66 (-1.76, -1.57) | -0.18 (-0.26, -0.09) | ||
Hypertensive heart disease | 13.08 (5.90, 26.76) | 33.36 (14.33, 69.08) | 9.11 (4.15, 18.20) | 17.70 (6.64, 38.45) | 22.04 (8.09, 47.48) | 8.20 (3.12, 17.26) | -1.43 (-1.56, -1.30) | -0.36 (-0.42, -0.31) | ||
Non-rheumatic valvular heart disease | 0.20 (0.09, 0.35) | 0.53 (0.23, 0.88) | 1.18 (0.54, 1.95) | 0.32 (0.15, 0.54) | 0.40 (0.18, 0.68) | 1.12 (0.52, 1.89) | -0.92 (-1.09, -0.75) | -0.19 (-0.25, -0.12) | ||
Cardiomyopathy and myocarditis | 0.62 (0.26, 1.08) | 1.57 (0.65, 2.70) | 0.97 (0.41, 1.68) | 0.74 (0.29, 1.37) | 0.92 (0.36, 1.68) | 0.80 (0.32, 1.47) | -1.85 (-1.88, -1.81) | -0.69 (-0.92, -0.46) | ||
Atrial fibrillation and flutter | 1.02 (0.53, 1.65) | 2.75 (1.44, 4.45) | 2.50 (1.40, 3.71) | 2.27 (1.25, 3.63) | 2.85 (1.56, 4.57) | 2.66 (1.55, 3.89) | 0.13 (0.10, 0.15) | 0.22 (0.19, 0.25) | ||
Aortic aneurysm | 0.47 (0.21, 0.81) | 1.15 (0.51, 2.00) | 2.26 (1.06, 3.66) | 0.70 (0.35, 1.15) | 0.85 (0.42, 1.40) | 2.08 (1.05, 3.34) | -1.06 (-1.19, -0.93) | -0.29 (-0.40, -0.19) | ||
Peripheral artery disease | 0.10 (0.04, 0.19) | 0.27 (0.11, 0.54) | 1.22 (0.55, 2.08) | 0.20 (0.09, 0.38) | 0.25 (0.11, 0.48) | 1.30 (0.60, 2.20) | -0.26 (-0.30, -0.22) | 0.23 (0.19, 0.27) | ||
Endocarditis | 0.20 (0.10, 0.33) | 0.45 (0.22, 0.74) | 1.97 (0.99, 3.27) | 0.28 (0.13, 0.50) | 0.34 (0.15, 0.62) | 1.55 (0.71, 2.69) | -0.92 (-1.07, -0.77) | -0.80 (-0.84, -0.76) | ||
Other cardiovascular and circulatory diseases | 1.50 (0.80, 2.43) | 3.56 (1.94, 5.75) | 2.34 (1.28, 3.67) | 1.92 (1.04, 3.04) | 2.33 (1.26, 3.69) | 2.10 (1.16, 3.26) | -1.45 (-1.50, -1.40) | -0.36 (-0.46, -0.27) | ||
Mental disorders | 25.18 (11.43, 43.54) | 44.18 (19.98, 76.61) | 2.80 (1.31, 4.70) | 27.16 (12.10, 48.35) | 35.70 (15.89, 63.6) | 2.29 (1.06, 3.89) | -0.74 (-0.75, -0.72) | -0.70 (-0.71, -0.69) | ||
Idiopathic developmental intellectual disability | 25.18 (11.43, 43.54) | 44.18 (19.98, 76.61) | 66.50 (35.59, 84.36) | 27.16 (12.1, 48.35) | 35.70 (15.89, 63.6) | 61.94 (32.07, 80.16) | -0.74 (-0.75, -0.72) | -0.25 (-0.25, -0.24) | ||
Diabetes and kidney diseases | 6.23 (3.73, 9.08) | 15.29 (9.19, 22.14) | 1.29 (0.76, 1.88) | 12.25 (7.08, 18.18) | 15.02 (8.68, 22.26) | 1.09 (0.62, 1.64) | -0.06 (-0.17, 0.04) | -0.57 (-0.67, -0.47) | ||
Chronic kidney disease | 6.23 (3.73, 9.08) | 15.29 (9.19, 22.14) | 3.16 (1.90, 4.63) | 12.25 (7.08, 18.18) | 15.02 (8.68, 22.26) | 2.92 (1.70, 4.33) | -0.06 (-0.17, 0.04) | -0.28 (-0.36, -0.21) |