Skip to main content

Table 2 The influence of various influencing factors on the prevalence of ARLD

From: Global prevalence, incidence, and outcomes of alcohol related liver diseases: a systematic review and meta-analysis

 

Studies (N)

ARLD (n)

Characteristic (%, 95%CI)

I2**

P

Race

46

4,828,061

   

 Caucasians

 

3,146,877

68.9% (67.6–70.2)

99.838

 < 0.001

 Africans

 

484,170

8.9% (8.5–9.4)

99.243

 < 0.001

 Hispanic

 

814,203

8.6% (7.9–9.4)

99.830

 < 0.001

 Asians

 

23,931

0.3% (0.1–0.6)

99.905

 < 0.001

Nationality

10

2078

   

 Minoritiesa

 

1299

61.6% (52.8–70.0)

93.630

 < 0.001

 Han

 

779

38.4% (30.0–47.2)

93.630

 < 0.001

Severity of disease

147

564,855

   

 Mild Alcoholic liver disease

 

9730

2.1% (1.3–3.0)

99.675

 < 0.001

 Alcoholic fatty liver disease

 

12,566

19.1% (17.0–21.4)

99.695

 < 0.001

 Alcoholic hepatitis

 

35,819

16.4% (13.4–19.6)

99.870

 < 0.001

 Alcoholic cirrhosis

 

348,848

32.9% (27.3–38.7)

99.939

 < 0.001

 Other

 

157,892

6.0% (3.0–9.8)

99.955

 < 0.001

By complication

119

3,527,134

   

 SBP

 

97,135

0.2% (0–0.5)

99.918

0.020

 Hepatorenal syndrome

 

193,512

0.7% (0.4–1.1)

99.820

 < 0.001

 Infection

 

119,448

2.4% (1.6–3.3)

99.935

 < 0.001

 Gastrointestinal haemorrhage

 

575,413

7.5% (6.0–9.2)

99.951

 < 0.001

 Encephalopathy

 

1,006,363

10.6% (8.8–12.6)

99.954

 < 0.001

 Ascites

 

1,465,780

25.1% (20.5–30.0)

99.986

 < 0.001

Duration of alcohol intake(yr)

19

4576

  

 < 0.001

 5–9(yr)

 

449

13.0% (9.1–17.5)

94.043

 < 0.001

 10–19(yr)

 

1187

29.5% (24.9–34.3)

90.974

 < 0.001

 ≥ 20(yr)

 

2940

54.8% (46.9–62.6)

96.366

 < 0.001

Daily dose of pure alcohol consumed (g/d)

20

4184

146.6 (123.8,169.4)

100

 < 0.001

Smoking

27

106,599

59.5% (55.9–63.1)

98.779

 < 0.001

By viral infection

67

1,473,951

  

 < 0.001

 HBV

 

11,712

3.6% (3.0–4.3)

99.637

 < 0.001

 HCV

 

66,744

5.6% (4.1–7.4)

99.932

 < 0.001

 HBV and/or HCV

 

92,548

18.7% (16.0–21.5)

99.929

 < 0.001

  1. Because some articles provide more than one characteristics of population with ARLD, they can be used for multiple subgroup analysis. Therefore, the sum of the articles and population data is not equal to the total
  2. ARLD Alcohol related liver disease, SBP Spontaneous bacterial peritonitis
  3. **All p values for I2 are lower than 0.05
  4. aThe minorities group included Mongol, Chosen, Li, Hmong, Kazak, Uyghurs, Xibe, Hani, Yi and Dai