Table 1 Sources and characteristics of GWAS summary data in the study
Phenotype | Data source | Sample size | Characteristics of subjects | Unit of data | Inclusion criteria of SNPs | No. of SNPs |
|---|---|---|---|---|---|---|
Telomere length | Codd et al. 2021 PMID: 34,611,362 | 472,174 | European Males and Females Aged 40-69 | SD | P < 5 × 10-8; r2=0.001, kb=1 M; F-statistic>10 | 96 |
Heavy smoking | Liu et al. 2019 PMID: 30,643,251 GSCAN a | 337,334 | European Males and Females Any age | SD | P < 5 × 10-8; r2=0.001, kb=1 M; F-statistic>10 | 19 |
Smoking initiation | Liu et al. 2019 PMID: 30,643,251 GSCAN | 1,232,091 | European Males and Females Any age | Log odds | P < 5 × 10-8; r2=0.001, kb=1 M; F-statistic>10 | 77 |
Age of smoking initiation | Liu et al. 2019 PMID: 30,643,251 GSCAN | 341,427 | European Males and Females Any age | SD | P < 5 × 10-6; r2=0.001, kb=1 M; F-statistic>10 | 20 |
Smoking cessation | Liu et al. 2019 PMID: 30,643,251 GSCAN | 547,219 | European Males and Females Any age | Log odds | P < 5 × 10-6; r2=0.001, kb=1 M; F-statistic>10 | 19 |
Maternal smoking | Ben Elsworth 2018 ID: ukb-b-17,685 MRC-IEU | 397,732 | European Males and Females Any age | SD | P < 5 × 10-6; r2=0.001, kb=1 M; F-statistic>10 | 50 |
Heavy drinking | Liu et al. 2019 PMID: 30,643,251 GSCAN | 941,280 | European Males and Females Any age | SD | P < 5 × 10-8; r2=0.001, kb=1 M; F-statistic>10 | 29 |
Body mass index | Yengo et al. 2018 PMID: 30,124,842 GIANT | 681,275 | European Males and Females Any age | SD | P < 5 × 10-8; r2=0.001, kb=1 M; F-statistic>10 | 443 |
Body fat percentage | Ben Elsworth 2018 ID: ukb-b-8909 MRC-IEU | 454,633 | European Males and Females Any age | SD | P < 5 × 10-8; r2=0.001, kb=1 M; F-statistic>10 | 315 |
IPF | Kurki et al. 2022 FinnGen | 340,596 | European Males and Females Mean age: 69.80 | SD | NA | NA |