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Table 2 The results of heterogeneity and horizontal pleiotropy tests

From: Dissecting the causal relationship between household income status and genetic susceptibility to cardiovascular-related diseases: Insights from bidirectional mendelian randomization study

Diseases

Heterogeneity test

Horizontal pleiotropy test

MR-Egger regression

IVW model

MR-Egger intercept

MR-PRESSO test

Coronary artery disease

0.034

0.036

0.462

-

Myocardial infarction

< 0.001

< 0.001

0.402

0.988

Heart failure

0.173

0.197

0.722

0.265

Atrial fibrillation

< 0.001

< 0.001

0.755

0.685

Hypertension

< 0.001

< 0.001

0.457

0.663

Ischemic stroke

0.195

0.223

0.780

0.202

Type 2 diabetes

< 0.001

< 0.001

0.291

0.831

  1. Note: IVW: Inverse Variance Weighting. P-value < 0.05 was considered as with statistical differences in both heterogeneity and horizontal pleiotropy tests
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BMC Public Health

ISSN: 1471-2458

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