Table 1 Incident cases and ASIR of myocarditis in 1990 and 2019, and temporal trends

Overall

780.41 (620.64-951.21)

16.74 (13.46-20.34)

1265.77 (1021.67-1531.51)

16 (13.01-19.28)

-0.23 (from -0.26 to -0.21)

Sex

 Female

324.88 (258.72-397.17)

13.66 (11.04-16.67)

537.86 (435.58-651.42)

13.1 (10.62-15.84)

-0.23 (from -0.27 to -0.2)

 Male

455.54 (363.9-557.22)

20.06 (16.21-24.31)

727.91 (585.21-879.25)

19.06 (15.51-22.89)

-0.25 (from -0.27 to -0.22)

Socio-demographic index

 High SDI

172.59 (138.52-210.56)

18.72 (15.07-22.8)

245.4 (200.09-298.32)

17.75 (14.71-21.22)

-0.41 (from -0.49 to -0.34)

 High-middle SDI

182.86 (145.26-222.76)

16.58 (13.32-20.18)

269.56 (215.85-328.11)

16.01 (12.94-19.34)

-0.16 (from -0.18 to -0.14)

 Middle SDI

229.79 (182.04-283.57)

16.39 (13.25-19.96)

379.02 (302.6-462.08)

15.79 (12.79-19.1)

-0.16 (from -0.17 to -0.14)

 Low-middle SDI

137.07 (109.45-168.1)

15.93 (12.9-19.29)

245.19 (195.46-298.49)

15.68 (12.73-18.97)

-0.064 (from -0.069 to -0.058)

 Low SDI

57.73 (45.98-71.2)

15.35 (12.43-18.68)

125.95 (100.11-155.46)

15.29 (12.38-18.59)

-0.0154 (from -0.0162 to -0.0146)

Region

 Andean Latin America

4.03 (3.24-4.93)

14.05 (11.38-17.11)

8.42 (6.8-10.22)

14.07 (11.41-17.1)

0.011 (0.005-0.018)

 Australasia

3.6 (2.86-4.38)

16.51 (13.25-19.98)

6.22 (5-7.53)

16.45 (13.31-19.83)

-0.02 (from -0.04 to -0.01)

 Caribbean

4.33 (3.48-5.24)

14.21 (11.5-17.19)

7.03 (5.69-8.56)

14.19 (11.48-17.16)

-0.0037 (from -0.0043 to -0.0031)

 Central Asia

8.77 (7.01-10.69)

14.84 (11.86-17.95)

12.5 (9.93-15.27)

14.87 (11.88-17.98)

0.01 (0.008-0.011)

 Central Europe

21.13 (16.81-25.81)

16.3 (13.13-19.83)

24.6 (19.63-30.18)

16.48 (13.27-20.05)

-0.004 (-0.037-0.029)

 Central Latin America

18.38 (14.77-22.57)

15.06 (12.18-18.32)

36.44 (29.39-44.45)

14.97 (12.11-18.2)

-0.02 (from -0.022 to -0.019)

 Central Sub-Saharan Africa

5.62 (4.43-6.93)

14.59 (11.72-17.82)

13.52 (10.6-16.74)

14.52 (11.67-17.7)

-0.017 (from -0.021 to -0.013)

 East Asia

192 (151.52-238.07)

17.92 (14.47-21.97)

283.46 (228.98-346.68)

16.86 (13.73-20.36)

-0.28 (from -0.32 to -0.23)

 Eastern Europe

42.7 (34.02-51.95)

17.64 (14.19-21.42)

46.06 (36.71-56.34)

17.74 (14.28-21.53)

0.016 (0.014-0.018)

 Eastern Sub-Saharan Africa

20.02 (15.81-24.71)

15.26 (12.33-18.61)

44.33 (35-54.8)

15.25 (12.32-18.59)

-0.007 (from -0.009 to -0.005)

 High-income Asia Pacific

37.57 (30.16-45.81)

20.66 (16.78-24.99)

54.82 (43.35-67.64)

20.07 (16.38-24.09)

-0.2 (from -0.24 to -0.17)

 High-income North America

63.62 (50.75-77.84)

19.91 (16.01-24.29)

87.79 (73.29-103.53)

18.21 (15.37-21.45)

-0.83 (from -1 to -0.66)

 North Africa and Middle East

31.37 (24.64-39.06)

12.01 (9.68-14.61)

64.13 (50.74-79.13)

12.05 (9.72-14.66)

0.018 (0.016-0.019)

 Oceania

0.76 (0.6-0.94)

15.3 (12.32-18.49)

1.61 (1.29-1.99)

15.3 (12.31-18.5)

0.0014 (-0.0001-0.0029)

 South Asia

133.98 (106.04-165.19)

16.28 (13.2-19.69)

259.99 (206.92-317.66)

16.18 (13.12-19.58)

-0.0225 (from -0.0232 to -0.0217)

 Southeast Asia

57.11 (45.43-70.28)

15.14 (12.27-18.41)

96.38 (76.49-117.56)

15.14 (12.26-18.38)

-0.004 (from -0.006 to -0.002)

 Southern Latin America

7.25 (5.84-8.78)

15.34 (12.43-18.64)

11.57 (9.37-14.07)

15.36 (12.45-18.66)

0.007 (-0.003-0.018)

 Southern Sub-Saharan Africa

6.33 (5.07-7.77)

15.72 (12.72-19.06)

10.73 (8.52-13.1)

15.73 (12.72-19.08)

0.004 (0.001-0.007)

 Tropical Latin America

19.02 (15.18-23.25)

15.76 (12.72-19.19)

36.76 (29.67-44.86)

15.72 (12.68-19.15)

-0.0084 (from -0.009 to -0.0078)

 Western Europe

81.39 (65.53-99.3)

17.56 (14.19-21.33)

109.54 (87.4-134.98)

17.47 (14.21-21.14)

-0.06 (from -0.09 to -0.03)

 Western Sub-Saharan Africa

21.43 (17.05-26.31)

15.48 (12.54-18.87)

49.89 (39.56-61.47)

15.37 (12.45-18.71)

-0.026 (from -0.031 to -0.021)