Table 2 The death cases and ASDR of syphilis in 1990 and 2019, and its temporal trends from 1990 to 2019

Overall

100450.82(34478.61, 210456.18)

1.55(0.54, 3.24)

83681.79(29799.16, 170424.22)

1.28(0.45, 2.62)

-1.06(-0.89, -1.23)

Sex

 Female

45227.69(15501.8, 95529.22)

1.43(0.5, 3.02)

37457.51(13274.55, 76846.46)

1.19(0.42, 2.45)

-1.05(-1.23, -0.87)

 Male

55223.13(19228.79, 116468.77)

1.68(0.61, 3.49)

46224.28(16529.86, 94506.42)

1.37(0.49, 2.81)

-1.08(-1.24, -0.92)

Socio-demographic index

 High SDI

381.33(240.9, 624.42)

0.05(0.03, 0.1)

225.08(122.03, 389.74)

0.03(0.01, 0.07)

-0.83(-0.42, -1.25)

 High-middle SDI

3057.75(1306.36, 6083.44)

0.3(0.13, 0.6)

1853.86(707.94, 3843.28)

0.23(0.08, 0.49)

-1.09(-0.91, -1.28)

 Middle SDI

16775.83(5866.53, 35721.78)

0.83(0.3, 1.75)

12510.01(4257.98, 26469.89)

0.72(0.24, 1.53)

-0.59(-0.55, -0.64)

 Low-middle SDI

30373.68(10158.33, 64878.54)

1.76(0.64, 3.69)

20727.25(7210.85, 43459.95)

1.23(0.43, 2.57)

-1.64(-1.39, -1.89)

 Low SDI

49767.85(17165.84, 104214.4)

4.65(1.71, 9.57)

48250.01(17373.4, 98217.26)

2.74(1.01, 5.54)

-2.12(-1.98, -2.26)

Region

 Andean Latin America

1177.14(360.49, 2564.95)

2.08(0.66, 4.5)

576.68(195.25, 1241.51)

0.91(0.31, 1.97)

-3.92(-3.6, -4.24)

 Australasia

4.36(3.47, 5.16)

0.02(0.02, 0.02)

2.46(1.82, 3.3)

0.01(0, 0.01)

-3.69(-2.52, -4.84)

 Caribbean

825.89(297.71, 1726.95)

1.95(0.73, 4.02)

986.9(368.8, 2004.84)

2.5(0.92, 5.1)

0.6(0.94, 0.26)

 Central Asia

146.97(78.78, 256.62)

0.19(0.11, 0.31)

123.93(44.64, 245.29)

0.14(0.05, 0.27)

-1.78(-1.34, -2.22)

 Central Europe

53.16(27.03, 100.01)

0.06(0.03, 0.11)

15.91(7.01, 31.52)

0.03(0.01, 0.06)

-3.06(-2.81, -3.31)

 Central Latin America

270.63(202.22, 382.23)

0.14(0.11, 0.19)

110.23(74.98, 167.18)

0.05(0.03, 0.08)

-3.68(-3.46, -3.9)

 Central Sub-Saharan Africa

8915.48(3085.41, 18093.59)

7.46(2.78, 14.83)

8586.87(2975.85, 17665.19)

4.16(1.49, 8.48)

-2.67(-2.39, -2.96)

 East Asia

4729.85(1663.84, 9944.49)

0.4(0.15, 0.83)

1999.23(705.64, 4395.83)

0.25(0.08, 0.57)

-0.88(-0.56, -1.19)

 Eastern Europe

172.81(93.07, 193.89)

0.07(0.04, 0.08)

27.1(21.31, 50.54)

0.01(0.01, 0.02)

-9.75(-8.09, -11.37)

 Eastern Sub-Saharan Africa

30239.21(10599.42, 62722.64)

7.65(2.91, 15.35)

25783.67(9524.82, 51886.89)

3.97(1.54, 7.9)

-2.56(-2.33, -2.8)

 High-income Asia Pacific

92.19(49.84, 170.05)

0.08(0.03, 0.16)

53.6(24.78, 102.69)

0.06(0.02, 0.14)

-0.13(0.21, -0.46)

 High-income North America

66.51(55.44, 70.78)

0.02(0.02, 0.02)

39.14(34.44, 46.15)

0.01(0.01, 0.01)

-3.52(-3.01, -4.03)

 North Africa and Middle East

2650.46(815.45, 6102.54)

0.48(0.15, 1.1)

2569.65(809.02, 5604.95)

0.44(0.14, 0.96)

-1.32(-0.91, -1.73)

 Oceania

626.77(210.18, 1333.79)

5.97(2.03, 12.67)

1084.37(363.94, 2200.24)

5.56(1.89, 11.25)

-0.76(-0.52, -1)

 South Asia

26799.73(8383.82, 58292.62)

1.65(0.57, 3.5)

14272.31(4795.63, 30905.7)

0.9(0.31, 1.94)

-2.66(-2.12, -3.19)

 Southeast Asia

5751.8(1815.41, 13013.94)

0.98(0.32, 2.18)

5639.9(1777.16, 12322.96)

1.07(0.33, 2.34)

0.47(0.68, 0.26)

 Southern Latin America

85.52(74.4, 96.43)

0.17(0.15, 0.2)

27.23(21.12, 34.95)

0.05(0.04, 0.06)

-3.98(-3.36, -4.59)

 Southern Sub-Saharan Africa

4496.69(1618.83, 9076.54)

6.27(2.3, 12.52)

2961.08(1044.09, 5975.18)

3.73(1.33, 7.51)

-1.81(-1.42, -2.19)

 Tropical Latin America

692.42(519.77, 940.23)

0.42(0.32, 0.57)

471.78(314.05, 716.32)

0.29(0.19, 0.45)

-0.84(-0.26, -1.41)

 Western Europe

171.18(126.49, 238.52)

0.05(0.03, 0.07)

75.27(40.39, 133.76)

0.03(0.01, 0.05)

-0.73(-0.05, -1.4)

 Western Sub-Saharan Africa

12482.04(4037.37, 27121.98)

3.02(1.01, 6.53)

18274.47(6046.07, 38226.97)

2.36(0.79, 4.93)

-0.7(-0.51, -0.88)