Table 2 MR estimates of associations between 3 types of exposure and MAFLD risk
Exposure | Number of SNPs | MR methods | outcome | OR(95%CI) | p-value |
|---|---|---|---|---|---|
Waist circumference | 180 | MR Egger | MAFLD | 1.74 (0.42,7.22) | 0.447 |
WME | 3.88 (1.81,8.29) | < 0.001 | |||
IVW | 3.53 (2.23,5.57) | < 0.001 | |||
Simple mode | 3.42 (0.57,20.42) | 0.179 | |||
Weighted mode | 3.58 (1.05,12.16) | 0.043 | |||
Waist-to-hip ratio | 29 | MR Egger | 1.38 (0.04,44.83) | 0.858 | |
WME | 1.87 (0.69,5.12) | 0.22 | |||
IVW | 2.29 (1.12,4.66) | 0.022 | |||
Simple mode | 2.56 (0.39,16.62) | 0.333 | |||
Weighted mode | 2.39 (0.495,11.49) | 0.288 | |||
Testosterone level | 135 | MR Egger | 1.67 (0.77,3.62) | 0.199 | |
WME | 1.71 (0.86,3.41) | 0.125 | |||
IVW | 1.93 (1.30,2.87) | 0.001 | |||
Simple mode | 2.32 (0.59,9.09) | 0.227 | |||
Weighted mode | 1.58 (0.80,3.14) | 0.192 |