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Table 4 Baseline characteristics of the participants across tertiles of SD for fasting plasma glucose in Multi-Ethnic Study of Atherosclerosis study

From: The association between fasting plasma glucose variability and incident eGFR decline: evidence from two cohort studies

Characteristics

With diabetes ( n  = 521)

T1 ( n  = 176)

T2 ( n  = 172)

T3 ( n  = 173)

P value

Age (year)

63.21 ± 9.13

64.85 ± 8.82

64.67 ± 8.85

60.10 ± 8.96

 < 0.001

Sex (women)

236 (45.30)

83 (47.16)

72 (41.86)

81 (46.82)

0.541

Marital status (married)

320 (61.42)

108 (61.36)

110 (63.95)

102 (58.96)

0.635

Education (high school and more)

281 (53.93)

105 (59.66)

86 (50.00)

90 (52.02)

0.161

Antihypertensive drug

317 (60.84)

106 (60.23)

114 (66.28)

97 (56.07)

0.148

Lipid-lowering drug

142 (27.26)

47 (26.70)

47 (27.33)

48 (27.75)

0.976

Current smoking

259 (49.71)

82 (46.59)

88 (51.16)

89 (51.45)

0.595

Moderate-high physical activity

279 (53.55)

96 (54.55)

91 (52.51)

92 (53.18)

0.947

BMI (Kg/m2)

30.51 ± 5.63

29.59 ± 5.18

30.88 ± 6.05

31.08 ± 5.58

0.028

WC (cm)

104.67 ± 14.19

102.84 ± 13.17

105.77 ± 15.06

105.43 ± 14.20

0.107

SBP (mmHg)

130.45 ± 20.19

129.15 ± 20.94

133.31 ± 19.96

128.95 ± 19.44

0.077

DBP (mmHg)

71.70 ± 9.39

70.91 ± 10.15

71.91 ± 8.65

72.29 ± 9.29

0.366

eGFR (mL/min/1.73 m2)

91.86 ± 20.19

88.19 ± 16.99

89.37 ± 19.02

98.06 ± 22.79

 < 0.001

FPG (mg/dl)

150.22 ± 53.21

127.13 ± 31.31

142.42 ± 39.19

181.46 ± 66.68

 < 0.001

FPG at phase 3 (mg/dl)

153.43 ± 58.79

126.86 ± 30.96

141.61 ± 36.31

192.23 ± 76.08

 < 0.001

FPG at phase 4 (mg/dl)

141.00 ± 50.74

127.35 ± 30.08

137.37 ± 39.12

158.49 ± 69.49

 < 0.001

Anti-diabetic drug at baseline

390 (74.86)

128 (72.73)

134 (77.91)

128 (73.99)

0.511

 

Without diabetes (n = 3,769)

T1 (n = 1,278)

T2 (n = 1,253)

T3 (n = 1,238)

P value

Age (year)

60.41 ± 9.89

60.78 ± 9.83

60.62 ± 9.91

59.83 ± 9.90

0.036

Sex (women)

1,968 (52.22)

685 (53.60)

631 (50.36)

652 (52.67)

0.245

Marital status (married)

2,394 (63.52)

804 (62.91)

815 (65.04)

775 (62.60)

0.385

Education (high school and more)

2,630 (69.78)

885 (69.25)

873 (69.67)

872 (70.44)

0.806

Antihypertensive drug

1,059 (28.10)

349 (27.31)

338 (26.98)

372 (30.05)

0.173

Lipid-lowering drug

490 (13.00)

154 (12.05)

159 (12.69)

177 (14.30)

0.227

Current smoking

1,858 (49.30)

591 (46.24)

642 (51.24)

625 (50.48)

0.025

Moderate-high physical activity

2321 (61.58)

797 (62.36)

763 (60.89)

761 (61.47)

0.746

BMI (Kg/m2)

27.57 ± 4.99

27.08 ± 4.80

27.40 ± 4.85

28.24 ± 5.25

 < 0.001

WC (cm)

95.77 ± 13.52

94.56 ± 12.95

95.45 ± 13.27

97.34 ± 14.18

 < 0.001

SBP (mmHg)

122.92 ± 20.21

123.13 ± 20.37

122.65 ± 19.95

122.97 ± 20.31

0.834

DBP (mmHg)

71.55 ± 10.03

71.63 ± 10.00

71.25 ± 9.84

71.79 ± 10.24

0.388

eGFR (mL/min/1.73 m2)

82.29 ± 13.76

82.31 ± 13.56

82.14 ± 13.40

82.42 ± 14.34

0.875

FPG (mg/dl)

87.51 ± 8.90

88.80 ± 7.45

87.67 ± 8.38

87.06 ± 10.63

0.089

FPG at phase 3 (mg/dl)

90.64 ± 8.58

88.56 ± 7.17

89.88 ± 7.63

93.57 ± 9.83

 < 0.001

FPG at phase 4 (mg/dl)

90.22 ± 8.71

88.39 ± 7.33

89.81 ± 8.18

92.52 ± 9.96

 < 0.001

  1. Data are represented as mean ± standard deviation for continuous variables and frequency (percent) for categorical variables
  2. T tertile, CVD cardiovascular disease, BMI body mass index, WC waist circumference, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, FPG fasting plasma glucose