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Table 2 AUC of TyG-BMI, BMI, TyG, TyG/HDL-C, TG, and the Model in predicting MAFLD risk

From: Comparison of the prognostic value of a comprehensive set of predictors in identifying risk of metabolic-associated fatty liver disease among employed adults

Variable

AUC

95%CI

Cut-off value

Sensitivity (%)

Specificity (%)

Youden's index

Total sample

 TyG-BMI

0.884

(0.877, 0.891)

218.284

0.817

0.783

0.599

 BMI

0.848

(0.839, 0.856)

24.615

0.763

0.760

0.523

 TyG

0.795

(0.785, 0.805)

8.771

0.779

0.677

0.456

 TG/HDL-C

0.782

(0.772,0.792)

1.146

0.762

0.676

0.438

 TG

0.778

(0.768, 0.788)

1.475

0.797

0.635

0.432

 Model

0.763

(0.753, 0.773)

-0.478

0.736

0.661

0.397

Training sample

 TyG-BMI

0.885

(0.877, 0.894)

217.401

0.827

0.772

0.599

 BMI

0.848

(0.838, 0.858)

24.335

0.798

0.725

0.524

 TyG

0.798

(0.786, 0.809)

8.788

0.772

0.692

0.464

 TG/HDL-C

0.783

(0.771, 0.795)

1.150

0.764

0.682

0.446

 TG

0.780

(0.768, 0.792)

1.475

0.802

0.634

0.436

 Model

0.766

(0.754, 0.779)

-0.426

0.712

0.690

0.401

Validation sample

 TyG-BMI

0.881

(0.868, 0.895)

219.406

0.813

0.794

0.607

 BMI

0.846

(0.831, 0.861)

24.555

0.768

0.756

0.524

 TyG

0.788

(0.770, 0.806)

8.713

0.804

0.638

0.442

 TG/HDL-C

0.780

(0.762, 0.798)

1.054

0.800

0.629

0.429

 TG

0.774

(0.755, 0.792)

1.525

0.766

0.657

0.423

 Model

0.757

(0.737, 0.776)

-0.400

0.710

0.688

0.398

  1. Abbreviation: AUC Area under the receiver operating characteristic curve, Model Prognostic index of prognostic model, MAFLD Metabolic-associated fatty liver disease, TyG Triglyceride and glucose index, BMI Body Mass Index, TG Triglycerides, HDL-C High-density lipoprotein cholesterol, CI Confidence interval