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Table 1 Baseline characteristics of participants in the Shahrekord cohort study (n = 9,151)

From: Sleep characteristics of middle-aged adults with non-alcoholic fatty liver disease: findings from the Shahrekord PERSIAN cohort study

Variables

NAFLD

Non-NAFLD

P

(N = 1,320)

(N = 7,831)

n (%)/ mean ± SD

n (%)/ mean ± SD

Demographic variables

 Age, year

50 ± 9

49 ± 9

 < 0.001

Sex

  

 < 0.001

 Male

479 (36.3)

3732 (47.7)

 

 Female

841 (63.7)

4099 (52.3)

 

Ethnicity

  

 < 0.001

 Fars

624 (47.3)

3043 (38.9)

 

 Turk

108 (8.2)

512 (6.5)

 

 Lur Bakhtiari

521 (39.5)

3966 (50.6)

 

 Others

67 (5.1)

310 (4)

 

Education

  

 < 0.001

 Illiterate

403 (30.5)

2560 (32.7)

 

  < Diploma degree

529 (40.1)

3422 (43.7)

 

  ≥ Diploma degree

380 (28.9)

1789 (22.8)

 

Marital status

  

 < 0.001

 Single

12 (0.9)

143 (1.8)

 

 Married

1253 (94.9)

7343 (93.8)

 

 Divorced

49 (3.7)

285 (3.6)

 

 Widowed

6 (0.5)

60 (0.8)

 

a Socioeconomic status

  

 < 0.001

 Low

330 (25)

2664 (34)

 

 Medium

459 (34.8)

2616 (33.4)

 

 High

519 (39.3)

2467 (31.5)

 

Anthropometric characteristics and metabolic parameters

 Weight, Kg

78.6 ± 13.4

72.3 ± 13.1

 < 0.001

 BMI, Kg/m2

29.9 ± 4.4

27.1 ± 4.5

 < 0.001

 Waist circumference, cm

99.4 ± 10.5

93.7 ± 11.3

 < 0.001

 Hip circumference, cm

103.9 ± 8.1

100.5 ± 7.7

 < 0.001

 Wrist circumference, cm

17.6 ± 1.5

17.3 ± 1.4

 < 0.001

 Total cholesterol, mg/dL

191 ± 40

184 ± 41

 < 0.001

 HDL cholesterol, mg/dL

51.1 ± 11.4

50.7 ± 11.6

0.31

 LDL cholesterol, mg/dL

105 ± 33

104 ± 33

0.44

 TG, mg/dL

174 ± 97

145 ± 85

 < 0.001

 Fasting glucose, mg/dL

102 ± 31

95 ± 25

 < 0.001

 AST, IU/L

21 ± 10

19 ± 8

 < 0.001

 ALT, IU/L

26 ± 17

21 ± 13

 < 0.001

 SBP, mmHg

117.6 ± 16.2

114.4 ± 17.2

 < 0.001

 DBP, mmHg

77.3 ± 10.5

74.9 ± 10.5

 < 0.001

Life style variables

 Physical Activity, METs

39.2 ± 6.4

41.4 ± 8.9

 < 0.001

 Smoking (yes)

158 (12)

1232 (15.7)

 < 0.001

 Alcohol Consumption (yes)

196 (14.8)

1263 (16.1)

0.13

 Using drug (yes)

151 (11.4)

1269 (16.2)

 < 0.001

Medical history and NAFLD severity assessments

 T2D (yes)

235 (28.8)

582 (13.4)

 < 0.001

 Hypertension (yes)

323 (24.5)

1047 (13.4)

 < 0.001

 MetS (yes)

436 (33)

1487 (19)

 < 0.001

 FLI

64.9 ± 23.2

46.9 ± 27.6

 < 0.001

 HSI

43.7 ± 13.1

36.9 ± 9.0

 < 0.001

Sleeping characteristics

 Sleeping time duration, hour

6.8 ± 1.5

6.9 ± 1.6

0.08

Sleeping time duration category, hour

  

0.11

  ≤ 7

825 (62.5)

4669 (59.6)

 

 7–9

379 (28.7)

2373 (30.3)

 

  ≥ 9

116 (8.8)

788 (10.1)

 

 Bedtime duration, hour

7.3 ± 1.5

7.3 ± 1.5

0.94

Bed time, hour,

  

 < 0.001

  ≤ 10 p.m

263 (19.9)

2046 (26.1)

 

 10 p.m.-12 a.m

559 (42.3)

3260 (41.6)

 

  ≥ 12 a.m

498 (37.7)

2524 (32.2)

 

Wake up time, hour

  

0.003

  ≤ 6 a.m

617 (46.7)

4035 (51.5)

 

 6–9 a.m

612 (46.4)

3363 (42.9)

 

  ≥ 9 a.m

91 (6.9)

433 (5.5)

 

Daytime nap (yes)

796 (60.3)

4206 (53.7)

 < 0.001

Daytime nap, hour

0.95 ± 0.6

0.96 ± 0.6

0.96

Sleep Efficiency (%)

92.3 ± 16.3

95.0 ± 34.3

 < 0.001

Falling asleep unintentionally (yes)

285 (21.6)

1508 (19.3)

0.05

Using sleeping pills (yes)

117 (8.9)

374 (4.8)

 < 0.001

Restless legs syndrome (yes)

195 (14.8)

916 (11.7)

0.002

  1. Data are presented as mean (SD) for continuous, and n (%) for categorical variables. P-values reported for t-test and chi-square test
  2. Abbreviations: SD standard deviation, T2D type 2 diabetes, MetS metabolic syndrome, HIS Hepatic Steatosis Index, FLI Fatty Liver Index, SBP systolic blood pressure, DBP diastolic blood pressure, AST aspartate aminotransferase, ALT alanine transaminase, HDL high-density lipoprotein, LDL low-density lipoprotein, TG triglycerides, NAFLD non-alcoholic fatty liver disease
  3. a Socioeconomic status was obtained by measuring several variables relating to income, occupation, and educational attainment. Principal component factor analysis was applied to these variables, and the first principal component was taken as a measure of socioeconomic status, and transformed to a three-category ordinal variable (low / medium / high) using its tertiles